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Showing results for "adverse events".
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61. Cervical Degenerative Disease Treatment: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/research
    February 01, 2024 - However, there were some differences in the frequency of adverse events for some comparisons. … However, there were some differences in the frequency of adverse events for some comparisons. … The likelihood of general or specific adverse events, such as need for reoperation/revision surgery, … events in many studies and heterogeneity in what harms and adverse events were described; studies reporting … Additionally, more explicit evaluation of procedure-specific (or device-specific) harms and adverse events

62. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
    May 08, 2023 - What is the frequency and severity of medication errors and adverse drug events? 2. … for 39% of all adverse events in the inpatient setting.3 Of these events, it is estimated that 27% … Medication Errors and Adverse Drug Events. … September 7, 2019. https://psnet.ahrq.gov/primer/medication-errors-and- adverse-drug-events. … Adverse drug events in ambulatory care.

63. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research-protocol
    December 01, 2019 - Outcomes: Disorder-specific and -nonspecific adverse events: Overall adverse events. … Specific adverse events: Major: mortality, cerebrovascular disease-related events, development of … Study withdrawals/time to withdrawal because of adverse events. … events include overall events, specific events, study withdrawals because of adverse events, time to … withdrawal because of adverse events, and persistence and reversibility of adverse events.

64. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, … switch rates) o Specific adverse events (including, but not limited to, weight gain, impaired renal … due to adverse events •Serious adverse events reported •Withdrawal rates •Switch rates Adult patients … Also, adverse events (including, but not limited to, weight gain, impaired renal function, angioedema … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, switch

65. Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive Disorder | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/major-depressive-disorder/research
    December 01, 2019 - Patients treated with SGAs had a higher risk of experiencing adverse events or discontinuing treatment … because of adverse events than patients treated with CBT, acupuncture, or St. … events for nonpharmacological treatment options. … SGAs, in general, lead to a higher risk of adverse events than nonpharmacological treatment options. … The evidence is insufficient to form conclusions about differences in serious adverse events, such as

66. Management of Infantile Epilepsies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
    March 01, 2023 - events for Lamotrigine Adverse Event Outcomes for Lamotrigine Findings Conclusion SOE   Non-serious … events for Phenytoin Adverse Event Outcomes for Phenytoin Findings Conclusion SOE   Non-serious events … events for Rufinamide Adverse Event Outcomes for Rufinamide Findings Conclusion SOE   Non-serious events … events for Stiripentol Adverse Event Outcomes for Stiripentol Findings Conclusion SOE   Any adverse … events for Topiramate Adverse Event Outcomes for Topiramate Findings Conclusion SOE   Bronchitis One

67. Peripheral Artery Disease (PAD) - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk of adverse cardiovascular events (MI, stroke, cardiovascular death) in patients with PAD? Is there a… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-diffe
    November 01, 2017 - cardiovascular events (MI, stroke, cardiovascular death) in patients with PAD? … cardiovascular events (MI, stroke, cardiovascular death) in patients with PAD? … Is clopidogrel more effective than aspirin in reducing adverse cardiovascular events in PAD? … It is associated with a 5 fold increased risk of adverse cardiovascular events. … peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-diffe

68. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
    December 01, 2019 - events Harms (KQ4, KQ5) Adverse effects (KQ4, KQ5) Adherence (KQ4, KQ5) Timing: … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. Methods A. … events Withdrawals because of adverse events Discontinuation rates because of adverse events Serious … adverse events Specific adverse events or withdrawals because of specific adverse events, including

69. Nonpharmacological Versus Pharmacological Treatment for Patients With Major Depressive Disorder: Current State of the Evidence (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
    September 01, 2016 - is a summary of a systematic review evaluating the evidence regarding the comparative benefits and adverse … events with SGAs when compared with CBT. … events, such as suicidal ideas and behavior, between SGAs and other therapies. … events and the rates of discontinuation due to adverse events may be similar for second-step therapies … events and rates of discontinuation due to adverse events were similar (1) when patients were switched

70. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - in adverse events methotrexate vs. quality of life from combination therapy of biologic in efficacy … In general, adverse events did not differ significantly between biologic and synthetic DMARDs. … Studies were too small to assess reliably differences in rare but severe adverse events. … Studies, however, were too small to assess reliably differences in rare but severe adverse events. … The groups did not differ in serious adverse events.

71. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - Differences in Harms (Adverse Events) (KQ 4a) We analyzed adverse-events data from 92 head-to-head efficacy … , and somnolence were commonly and consistently reported adverse events. … events such as suicidality, seizures, cardiovascular adverse events, serotonin syndrome, hyponatremia … Other Severe Adverse Events The existing evidence on the comparative risk for rare but severe adverse … Adverse-events profiles High Adverse-events profiles, based on 92 efficacy trials and 48 studies of

72. Prioritization and Selection of Harms for Inclusion in Systematic Reviews (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - Harms are Adverse Events or Complications • Definition of harms: ► Adverse events or complications … Consider Composite Adverse Events (II) • “Serious adverse events” or “withdrawal due to adverse events … Consider Composite Adverse Events (II) Two composite adverse events are particularly useful to consider … , the first is “serious adverse events” while the second is “withdrawal due to adverse events.” … Consider Composite Adverse Events (I) 6. Consider Composite Adverse Events (II) 7.

73. Antipsychotics-Children Research-Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - This includes: 1) Overall adverse events; 2) Specific adverse events; 3) Withdrawals/time to withdrawal … due to adverse events; 4) Persistence and reversibility of adverse events. … events, withdrawal due to adverse events, persistence and reversibility of adverse events. … Adverse events include overall events, specific events, withdrawals due to adverse events, time to withdrawal … due to adverse events, and persistence and reversibility of adverse events

74. Making Healthcare Safer IV: Summary of Findings on Patient Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/summary-findings
    December 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events 1a. … Whereas the TEP encouraged implementation of CDSS to reduce medication errors and adverse drug events … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a. … CDSS to reduce medication errors and adverse drug events. … Adverse Events in Hospitals: A Quarter of Medicare Patients Experienced Harm in October 2018. U.S.

75. Radiation Therapy for Brain Metastases: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-brain-metastases/protocol
    June 01, 2021 - The broader inclusion criteria for adverse event data take into account that rare adverse events are … of adverse events The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting will also assess whether adverse events, including serious adverse events, were defined … events) Number of patients with serious adverse events Number of adverse events Any specific … Associations of adverse events with an intervention will be based on comparative evaluations, and events

76. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - To date, no study has evaluated proximal clinical measures, long-term effects, and adverse events among … Gastrointestinal adverse events/problems. … , and consistently report all adverse events (not using aggregated events). … GI adverse events (range 2-63%) compared with thiazolidinediones events (range 0-36%) and second-generation … medications in withdrawals due to unspecified adverse events. events 4&5k.

77. Disposition of comments_Comparative Effectiveness Review No. 244: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
    May 25, 2021 - zero events as many adverse events are rare, this approach is not optimal as it does not directly … However, we do provide all rates of key adverse events in the Summary of Findings tables. … Maybe “A limited number of studies included listed adverse events stratified…”. … Peer Reviewer #5 Results p. 36, line 43: States “severe and serious adverse events”. … We pre-specified key adverse events of interest with our technical expert panel.

78. Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/ptsd-adult-treatment-update/research-2018
    October 01, 2019 - The majority of psychological studies reported no information about adverse events; pharmacological treatment … studies did not appear to be associated with any significant adverse events (only venlafaxine appears … Studies provided insufficient strength of evidence for serious adverse events associated with any treatments … The majority of psychological studies reported no information about adverse events. … events associated with treatments.

79. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … Action Plan) identified anticoagulants as a leading cause of adverse drug events.9 For example, between … MHS II10 expanded this scope to include interventions aimed at reducing adverse events linked to intravenous … events related to anticoagulants. … US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014.

80. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - events (RR 0.75, 95% CI 0.70 to 0.80) and withdrawals due to GI adverse events (RR 0.45, 95% CI 0.33 … , any GI adverse events (RR 0.31, 95% CI 0.24 to 0.39), and withdrawals due to GI adverse events (RR … , 95% CI 0.70 to 0.99), but there was no difference in risk of GI adverse events, withdrawal due to adverse … events, or withdrawal due to GI adverse events. … events and higher risk of dermatologic adverse compared to oral NSAIDs.