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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common
lorcaserin-related adverse events. U.S. … Common adverse
events were headache, back pain, nasopharyngitis, and nausea.
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effectivehealthcare-admin.ahrq.gov/products/headaches-pregnancy/research
June 01, 2022 - Events Outcome Intervention Comparison Studies Subjects Finding SOE Any Antiemetics: Metoclopramide … + Antihistamines: Diphenhydramine Opioid analgesics: Codeine 1 70 No events in either arm low Serious … Events Outcome Intervention Comparison Studies Subjects Finding SOE Any Nonpharmaceutical: transcranial … Events Outcome Intervention Comparison SRs/Studies Finding SOE Any serious IV magnesium none 1/5 Increased … Events Outcome Intervention Comparison SRs/Studies Finding SOE Any Antiepileptics: gabapentin none
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effectivehealthcare-admin.ahrq.gov/health-topics/patient-safety?page=0
April 02, 2025 - Medication Harms in Older Adults
Rapid Evidence Product January 16, 2024
Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults
Rapid Evidence Product November 7, 2023 … Protocol September 29, 2023
Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse … Drug Events Related to Anticoagulants
Research Protocol September 29, 2023
Making
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effectivehealthcare-admin.ahrq.gov/health-topics/patient-safety
April 02, 2025 - Medication Harms in Older Adults
Rapid Evidence Product January 16, 2024
Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults
Rapid Evidence Product November 7, 2023 … Protocol September 29, 2023
Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse … Drug Events Related to Anticoagulants
Research Protocol September 29, 2023
Making
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effectivehealthcare-admin.ahrq.gov/products/omega-3-maternity/research
April 01, 2021 - Adverse events
Prenatal and infant supplementation with n-3 FA or fortification of foods with n-3 FA … did not result in any serious or nonserious adverse events (moderate SoE); with the exception of an … Nov 15, 2024
Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events … Protocol
Nov 15, 2024
Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - Adverse effects of intervention(s): withdrawals due to
adverse events, nausea/vomiting, diarrhea, anorexia … Naltrexone
One study 24 (n=128) reported no serious adverse
events, but an increase in sleepiness … Baclofen
There were no serious adverse events related to
baclofen in two studies: one RCT (n=56), 23 … The
majority of serious adverse events in the placebo
group (88%) and the nalmefene group (76%) were … They reported mental slowing, a reduction in verbal
fluency and working memory as adverse events
among
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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common lorcaserin-related
adverse events. U.S. … Common
adverse events were headache, back pain, nasopharyngitis, and nausea.
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effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
December 01, 2019 - cardiovascular events. … cardiovascular events; however they reached contradictory conclusions. … effects of test-directed treatment (including bleeding events and other adverse events such as gastrointestinal … events and liver toxicity)
Adverse effects of testing per se (including test-related anxiety and adverse … events secondary to venipuncture).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
July 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments
had few minor adverse effects. … Longer term information on benefits and
adverse effects would better inform clinical decisions for … Substantial and life-
altering adverse events sometimes occur after surgery for
fecal incontinence, … and these events were underidentified
in randomized controlled trials (RCTs) alone.
�� Addressing the
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
June 01, 2015 - events;
withdrawals due to adverse events; and sources of funding. … Although
cisplatin is nephrotoxic, renal adverse events were not
well reported.28 No study compared … radical cystectomy:
adverse events
Insufficient
There was insufficient evidence from 4 studies of … with grade 3 or 4
hematological adverse events. … Adjuvant
chemotherapy
vs. no adjuvant
chemotherapy:
adverse events
Insufficient
Harms were poorly
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - o Treatment discontinuation due to adverse effects. … For categorical variables we will abstract the number of events among treatment
groups to calculate … percent CI, we will calculate the
relative risk and absolute risk difference from the abstracted events … Time course of adverse events most commonly
associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo
groups of anti-migraine clinical trials.
-
effectivehealthcare-admin.ahrq.gov/products/allergy-seasonal/research-protocol
December 01, 2020 - events. … events resulting from systemic absorption, such as impaired bone growth, reduced height, suppression … events in SAR research. … Additionally, systematic reviews and meta-analyses that specifically assess adverse events associated … events, and results.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - For categorical
variables, we abstracted the number of events among
treatment groups to calculate rates … We used default software
continuity coefficients for 0 events and intention to
treat as recommended … The number
of avoided or excessive events per population of 1,000 is
the difference between the two … Time course of adverse
events most commonly associated with topiramate for migraine
prevention. … A systematic review of
adverse events in placebo groups of anti-migraine clinical trials.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Comparison of the sample size, primary outcome, and withdrawals due to adverse
events reported in the … ClinicalTrials.gov began to mandate reporting of adverse
events in September 2009 as serious adverse … events and non-serious adverse events. … We
compared the total adverse events reported in ClinicalTrials.gov with the total reported in
the … CT.gov reported more adverse
events.
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effectivehealthcare-admin.ahrq.gov/products/high-cholestorol-medicines-update/research-protocol
December 01, 2019 - events when compared with statin monotherapy. … The previous CER initially intended to examine the long-term benefits and rates of serious adverse effects … event; withdrawal due to an adverse event; cancer; serum AST and/or serum ALT elevated ≥3 times the … Ridker PM, Rifai N, Pfeffer MA, et al; Cholesterol and Recurrent Events Investigators. … Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - Few adverse
drug withdrawal events resulted from deprescribing interventions. … drug events,
adverse drug withdrawal events, mortality)
Implementation measures
(e.g., barriers … Importantly, deprescribing was associated with few adverse drug withdrawal events. … Adverse
drug events in ambulatory care. … Reducing Adverse Drug Events in Older
Adults.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - events that should be
followed up. … events
data from different studies,
adverse events reported
generally were consistent with
known … Relation between kidney function,
proteinuria, and adverse outcomes. … Raloxifene was associated with
significantly fewer kidney-related adverse
events compared with placebo … events data from different
studies, adverse events reported generally
were consistent with known potential
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … KQ 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - • Serious adverse events,
events leading to treatment
discontinuation, and treatment site
infections … Adverse Events, All BCC Lesions
In Table B drugs were most likely to have adverse events
leading to … Events
Leading to
Discontinuation
(95% CI)
Serious
Adverse
Events (95%
CI)
Adverse
Events: … Adverse Events, All SCCIS Lesions
In Table C the highest mean frequency of adverse events
leading to … Adverse events
were inconsistently reported.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - Example binary data for effect size computation
Treatment
Events in
Treatment
Group
Treatment
n … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse … Events. … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse … Events.