-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - Differences in Harms (Adverse Events) (KQ 4)
We analyzed adverse events data from 72 head-to-head
efficacy … Methods of adverse events assessment in efficacy trials
differed greatly. … Adverse events profiles. … Severe adverse events.
Sexual dysfunction. … Other severe adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - The adverse events and harms reported by any
studies included to address any of the other questions
were … used to address questions about harms and
adverse events. … In addition, we searched specifically
for reports of harms and adverse events associated
with the use … Six studies reported
adverse events such as pain and minor rectal bleeding. … None of the included studies reported any adverse events
related to CT or PET/CT.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - The most commonly
reported adverse events were injection site reactions,
flulike symptoms, depression … Serious
adverse events were generally not reported, although
two studies gave rates of about 25 percent … of efficacy and other reasons
not necessarily related to adverse events or side effects. … Dropouts
from observational studies are more likely to bias reporting
toward lack of adverse events … Adverse events and inefficacy or
progression of disability were two expected categories.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
October 12, 2023 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and Adverse … Events (AEs), Including Withdrawals Due AEs Funding Source Quality Comments
Ryu, 2023 1 SBRT vs. … AEs by type, number of patients with an AE (cannot calculate n/Ns because no way to tell if multiple events … See above
Addendum Appendix Abbreviations
Abbreviations for Addendum Appendix
Acronym Term
AE adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
March 01, 2025 - regarding participant
experience, validity and diagnostic accuracy of the screening tool or approach, or
adverse … events associated with the screening process … systematic effect (RR 0.41; CI 0.01,
13.72)
Low for benefit
Expert-facilitated
Support Group
Adverse … Support Loneliness N/A Insufficient
Peer Support Suicide outcomes N/A Insufficient
Peer Support Adverse … events associated with
interventions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - Partogram use: Evidence summary for major outcomes and adverse events
Category Outcome
Study Design … Low
(non-U.S. setting, 1
study)
Adverse
Events
Maternal
Outcomes –
Hemorrhage
3 RCTs24,25,29 … Moderate
(Indirect,
consistent)
Existing SR
was consistent
with RCT
findings
Adverse
Events … High
Adverse
Events
Maternal Outcomes –
Infection
3 RCTs37
(1,933)
2 SRs44-46
(3,475 patients … Low
(Indirect, 1 study)
Adverse
Events
Maternal
Outcomes –
Trauma to the
Pelvic Floor
1 RCT76
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
June 15, 2011 - adverse treatment effects may manifest in less than 1 year. … events, and adherence. … The quality of RCTs and observational
cohort studies reporting adverse events will be evaluated by … events according to: patient demographic and comorbid characteristics (age, gender,
race, baseline … Risk of renal stone events in primary
hyperparathyroidism before and after parathyroid surgery: controlled
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
December 01, 2011 - In patients with ACS who are undergoing PCI of
native vessels, how do the rate and type of adverse
events … The outcomes are
separated into adverse events, intermediate outcomes,
and final health outcomes. … The adverse events of note
include coronary dissection, perforation, and prolonged
procedure time. … Only two direct comparative
randomized trials evaluated for adverse events.51,52 Both
of these direct … There was a paucity of trials available to
evaluate adverse events with any of the embolic
protection
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - Collection of adverse events data was notably inconsistent
across studies. … In particular, although some studies reported all adverse events, others
only reported them in the situation … Trials of topiramate
reported increased risks of many adverse events, including paresthesias, taste … For most serious harms, there was insufficient data to
determine comparative rates of adverse events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - drug events) and real (adverse drug events being a subset of the drug
related problems) drug related … Adverse Drug Events
The assessment of a medication therapy management program designed to impact
adverse … We chose a validated research tool to
assess adverse drug events. … The costs associated with adverse drug
events among older adults in the ambulatory
setting. … Risk factors for adverse drug events among
older adults in the ambulatory setting.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
November 24, 2014 - events (safety and tolerability): overall adverse events, withdrawals
because of adverse events, serious … adverse events, specific adverse events
(including hyponatremia, seizures, suicidality, hepatotoxicity … events, or drug interactions (pharmacologic and alternative
treatments)
Timing
We will have no … events, results, and adverse events
reported. … events, if reported.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Summary outcomes, adverse events, and strength of evidence of treatments for
CUR in mixed populations … effects
Serious adverse events NS NA
Ghalayini 200513
(n=51)
TURP vs. … effects
Any adverse events NS NA
de Sèze 200217 (n=13)
Botulinum A toxin vs. … effects:
Any adverse events NS NA
Chen 200416 (n=21)
Botulinum A toxin vs. … Summary outcomes, adverse events, and strength of evidence of treatments for CUR in
mixed populations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
April 10, 2020 - Therefore, it is not clear how serious adverse events are
defined or qualified for the purpose of the … If the serious adverse
events aren’t defined by industry standards, AACAP recommends that
the term … Public reviewer:
AACAP
Measure-
ment of
Adverse
Outcomes/
Events
The Review brings attention … Some terms are not well-defined
such as “mixed
depressive disorders” and “serious adverse events”. … We also added text to
methods section on “serious adverse
events.”
-
effectivehealthcare-admin.ahrq.gov/products/emt-naloxon/systematic-review
August 01, 2019 - Six studies reported low rates of deaths and serious adverse events (0% to 1.25%) in patients not transported … concentration IN naloxone (2 mg/1 mL) is similar in efficacy to IM naloxone (2 mg), with no difference in adverse … events. … overdose is associated with a low rate of serious harms, but patients were probably at low risk for such events
-
effectivehealthcare-admin.ahrq.gov/products/stroke-afib-update/research-2018
May 01, 2020 - Higher adverse events (excessive bleeding or procedure-related complications) were observed with LAA … and reductions (apixaban) or similar (dabigatran) rates in bleeding events when compared with warfarin … Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic … Technical Expert Panel, 2023-2024
Rapid Evidence Product
Jan 16, 2024
Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults
Page last reviewed
-
effectivehealthcare-admin.ahrq.gov/products/stereotactic-body-radiation/technical-brief
December 01, 2019 - and size, comparators, concurrent and/or prior treatments, length of followup, outcomes measured, and adverse … events. … The most frequently reported adverse events include pain, fatigue, nausea, bleeding, and diarrhea.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plant-based-treatments-draft-report-2025-cohort-table-app-e.xlsx
January 01, 2025 - Events Other Reported Outcomes Funding Source Risk of Bias
21087411 Bestard, 2011 Prospective cohort … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse … events: 4.65% (10/215) vs.
-
effectivehealthcare-admin.ahrq.gov/products/deprescribing-mhs4/protocol
August 01, 2023 - drug events (ADEs), increased healthcare utilization (e.g., emergency department visits, acute care … drug events, adverse drug withdrawal events, mortality)
Implementation measures (e.g., barriers … Adverse drug events in ambulatory care. … Clarifying adverse drug events: a clinician's guide to terminology, documentation, and reporting. … Reducing Adverse Drug Events in Older Adults.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - Events: The incidence of other adverse events i.e. dermatitis 7 and dysphagia 6
favored IMRT treatment … The original CER reported
inconsistent results for other adverse events. … events. … Similarly
inconsistent results
for adverse events
were found in the
original CER
1 signal (A1) … events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - events, or lower medical utilization:
a. … events outcomes). … The safety outcomes will be framed to help
identify adverse events, including aspiration, secondary … events; and
intermediate, final, and adverse events outcomes. … intervention-group
rates of events, or both.