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  1. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
    January 01, 2007 - Differences in Harms (Adverse Events) (KQ 4) We analyzed adverse events data from 72 head-to-head efficacy … Methods of adverse events assessment in efficacy trials differed greatly. … Adverse events profiles. … Severe adverse events. Sexual dysfunction. … Other severe adverse events.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - The adverse events and harms reported by any studies included to address any of the other questions were … used to address questions about harms and adverse events. … In addition, we searched specifically for reports of harms and adverse events associated with the use … Six studies reported adverse events such as pain and minor rectal bleeding. … None of the included studies reported any adverse events related to CT or PET/CT.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
    April 01, 2015 - The most commonly reported adverse events were injection site reactions, flulike symptoms, depression … Serious adverse events were generally not reported, although two studies gave rates of about 25 percent … of efficacy and other reasons not necessarily related to adverse events or side effects. … Dropouts from observational studies are more likely to bias reporting toward lack of adverse eventsAdverse events and inefficacy or progression of disability were two expected categories.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    October 12, 2023 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and AdverseEvents (AEs), Including Withdrawals Due AEs Funding Source Quality Comments Ryu, 2023 1 SBRT vs. … AEs by type, number of patients with an AE (cannot calculate n/Ns because no way to tell if multiple events … See above Addendum Appendix Abbreviations Abbreviations for Addendum Appendix Acronym Term AE adverse
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
    March 01, 2025 - regarding participant experience, validity and diagnostic accuracy of the screening tool or approach, or adverseevents associated with the screening process … systematic effect (RR 0.41; CI 0.01, 13.72) Low for benefit Expert-facilitated Support Group Adverse … Support Loneliness N/A Insufficient Peer Support Suicide outcomes N/A Insufficient Peer Support Adverseevents associated with interventions.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
    May 01, 2020 - Partogram use: Evidence summary for major outcomes and adverse events Category Outcome Study Design … Low (non-U.S. setting, 1 study) Adverse Events Maternal Outcomes – Hemorrhage 3 RCTs24,25,29 … Moderate (Indirect, consistent) Existing SR was consistent with RCT findings Adverse Events … High Adverse Events Maternal Outcomes – Infection 3 RCTs37 (1,933) 2 SRs44-46 (3,475 patients … Low (Indirect, 1 study) Adverse Events Maternal Outcomes – Trauma to the Pelvic Floor 1 RCT76
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
    June 15, 2011 - adverse treatment effects may manifest in less than 1 year. … events, and adherence. … The quality of RCTs and observational cohort studies reporting adverse events will be evaluated by … events according to: patient demographic and comorbid characteristics (age, gender, race, baseline … Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled
  8. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
    December 01, 2011 - In patients with ACS who are undergoing PCI of native vessels, how do the rate and type of adverse events … The outcomes are separated into adverse events, intermediate outcomes, and final health outcomes. … The adverse events of note include coronary dissection, perforation, and prolonged procedure time. … Only two direct comparative randomized trials evaluated for adverse events.51,52 Both of these direct … There was a paucity of trials available to evaluate adverse events with any of the embolic protection
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
    November 01, 2023 - Collection of adverse events data was notably inconsistent across studies. … In particular, although some studies reported all adverse events, others only reported them in the situation … Trials of topiramate reported increased risks of many adverse events, including paresthesias, taste … For most serious harms, there was insufficient data to determine comparative rates of adverse events
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
    July 01, 2012 - drug events) and real (adverse drug events being a subset of the drug related problems) drug related … Adverse Drug Events The assessment of a medication therapy management program designed to impact adverse … We chose a validated research tool to assess adverse drug events. … The costs associated with adverse drug events among older adults in the ambulatory setting. … Risk factors for adverse drug events among older adults in the ambulatory setting.
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
    November 24, 2014 - events (safety and tolerability): overall adverse events, withdrawals because of adverse events, serious … adverse events, specific adverse events (including hyponatremia, seizures, suicidality, hepatotoxicity … events, or drug interactions (pharmacologic and alternative treatments) Timing We will have no … events, results, and adverse events reported. … events, if reported.
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
    September 01, 2014 - Summary outcomes, adverse events, and strength of evidence of treatments for CUR in mixed populations … effects Serious adverse events NS NA Ghalayini 200513 (n=51) TURP vs. … effects Any adverse events NS NA de Sèze 200217 (n=13) Botulinum A toxin vs. … effects: Any adverse events NS NA Chen 200416 (n=21) Botulinum A toxin vs. … Summary outcomes, adverse events, and strength of evidence of treatments for CUR in mixed populations
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
    April 10, 2020 - Therefore, it is not clear how serious adverse events are defined or qualified for the purpose of the … If the serious adverse events aren’t defined by industry standards, AACAP recommends that the term … Public reviewer: AACAP Measure- ment of Adverse Outcomes/ Events The Review brings attention … Some terms are not well-defined such as “mixed depressive disorders” and “serious adverse events”. … We also added text to methods section on “serious adverse events.”
  14. effectivehealthcare-admin.ahrq.gov/products/emt-naloxon/systematic-review
    August 01, 2019 - Six studies reported low rates of deaths and serious adverse events (0% to 1.25%) in patients not transported … concentration IN naloxone (2 mg/1 mL) is similar in efficacy to IM naloxone (2 mg), with no difference in adverseevents. … overdose is associated with a low rate of serious harms, but patients were probably at low risk for such events
  15. effectivehealthcare-admin.ahrq.gov/products/stroke-afib-update/research-2018
    May 01, 2020 - Higher adverse events (excessive bleeding or procedure-related complications) were observed with LAA … and reductions (apixaban) or similar (dabigatran) rates in bleeding events when compared with warfarin … Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic … Technical Expert Panel, 2023-2024 Rapid Evidence Product Jan 16, 2024 Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults Page last reviewed
  16. effectivehealthcare-admin.ahrq.gov/products/stereotactic-body-radiation/technical-brief
    December 01, 2019 - and size, comparators, concurrent and/or prior treatments, length of followup, outcomes measured, and adverseevents. … The most frequently reported adverse events include pain, fatigue, nausea, bleeding, and diarrhea.
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plant-based-treatments-draft-report-2025-cohort-table-app-e.xlsx
    January 01, 2025 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07) Serious adverse events: none in any group Withdrawals due to adverse eventsadverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04) Withdrawals due to adverseevents: 4.65% (10/215) vs.
  18. effectivehealthcare-admin.ahrq.gov/products/deprescribing-mhs4/protocol
    August 01, 2023 - drug events (ADEs), increased healthcare utilization (e.g., emergency department visits, acute care … drug events, adverse drug withdrawal events, mortality) Implementation measures (e.g., barriers … Adverse drug events in ambulatory care. … Clarifying adverse drug events: a clinician's guide to terminology, documentation, and reporting. … Reducing Adverse Drug Events in Older Adults.
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
    August 01, 2012 - Events: The incidence of other adverse events i.e. dermatitis 7 and dysphagia 6 favored IMRT treatment … The original CER reported inconsistent results for other adverse events. … events. … Similarly inconsistent results for adverse events were found in the original CER 1 signal (A1) … events.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
    April 21, 2011 - events, or lower medical utilization: a. … events outcomes). … The safety outcomes will be framed to help identify adverse events, including aspiration, secondary … events; and intermediate, final, and adverse events outcomes. … intervention-group rates of events, or both.

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