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Showing results for "adverse events".
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281. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
     February 01, 2008 - events such as neurological adverse effects, hypotension, rash, suicidal ideation, mood and cognition … Based on the comments received and input from the Technical Expert Panel, the adverse events listed … effects • Cosmetic adverse events • Incidence of adverse events • Incidence of individual adverse … events • Incidence of adverse events resulting in therapy withdrawal • Incidence of adverse events … not resulting in therapy withdrawal • Skin rash • Neurological adverse events • Suicidal ideation

282. Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
     December 01, 2019 - Question 3 . . . clinical or intermediate harms outcomes (e.g., organ toxicity, serious adverse events … , withdrawal due to adverse events)? … events Serious adverse events (composite outcome) c Neurologic adverse events (e.g., neuropathy … clinical adverse events Organ toxicity Liver (aspartate aminotransferase [AST], alanine … events (composite outcome—FDA definition of serious adverse events 24 ), withdrawal due to adverse events

283. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
     January 01, 2024 - that have potential analgesic effects as well as the potential for addiction, misuse, and serious adverse … There may be no increase in risk of serious adverse events (SOE: low) or withdrawal due to adverse events … Other prioritized adverse events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … events, such as CUD, psychosis, and cognitive deficits. … Compared with placebo, these interventions resulted in greater risk of common adverse events (dizziness

284. Failure To Rescue – Rapid Response Systems | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mhs4-failure-rescue/rapid-research
     March 01, 2024 - Serious adverse events (e.g., intubation and need for mechanical ventilation, arrest soon after ICU arrival … incidence of cardiorespiratory arrest, hospital mortality, transition to higher level of care, serious adverse … events related to clinical deterioration, or unintended consequences. … Serious adverse events (e.g., arrest soon after ICU arrival) were infrequently reported (insufficient

285. Colorectal-Surgery-Preparation Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
     April 01, 2014 - For Key Question 2 we considered the following prespecified adverse events (harms): nausea; vomiting … severity of patient-reported adverse events (nausea, vomiting, fatigue, bloating, cramping, etc.). … Almost universally, the rates of reported adverse events were below 4 percent. … No studies reported adverse events by any of the prespecified subgroups of interest. … Hartmann's reversal is associated with high postoperative adverse events.

286. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
     August 06, 2018 - events (AEs); that is, some interventions Source: www.effectivehealthcare.ahrq.gov Published … All guidelines suggest active monitoring for potential adverse events and ensuring that the treatment … Adverse events may occur at any point after the treatment is received. IV. … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome

287. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis – An Update to the 2006 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/osteoarthritis-pain/research-protocol
     December 01, 2019 - Also, adverse events may occur at any point after the treatment is received. Methods A. … We assumed that the adverse events occurred independently and that the logarithm of the rate ratios was … After estimating the effect (number of events prevented or caused) for each of the three adverse events … , we estimated the net effects on all three serious adverse events using Monte Carlo simulation. … We also pooled clinical success rates and withdrawal due to adverse events from head-to-head trials of

288. Deprescribing To Reduce Medication Harms in Older Adults | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/deprescribing-mhs4/rapid-research
     February 01, 2024 - Few adverse drug withdrawal events resulted from deprescribing interventions. … Healthcare Safer IV: Opioid Stewardship Rapid Evidence Product | Jan 16, 2024 Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults Rapid Evidence Product | Feb 9, 2024 … Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events View

289. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
     November 26, 2024 - cognitive impairment, and substance use disorders.10 This project will investigate the epidemiology and adverse … events)  Psychological outcomes o Long-term  Health measures  Psychological outcomes  Employment … term")) OR (title: ("long term")) OR (title: ("longer term")) OR (title: (outcomes)) OR (title: ("adverse … event")) OR (title: ("adverse events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … event")) OR (abstract: ("adverse events")) OR (abstract: (consequence)) OR (abstract: (consequences

290. App-D-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
     September 30, 2015 - Events and Withdrawals Due to Adverse Events Sponsor Quality Hruschak, 2021 RCT Duration: 6 weeks University … to study medications: 12.7% (7/55) vs. 29.1% (16/55), RR 0.44 (95% CI 0.20 to 0.98) Serious AEs: No events … B (events/total person-years); adjusted Incidence Rate Ratio (aIRR): Overdose: 3241/22097 vs. 11433/ … cardiovascular events (including ischemic heart disease, congestive heart failure, acute ischemic stroke … B Major adverse cardiovascular events: 52 vs. 72 Incidence rate per 10,000 person months (95% CI): 30.12

291. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
     January 01, 2007 - blood pressure control, preservation of kidney function, flash pulmonary edema, other cardiovascular events … What adverse events and complications have been associated with aggressive medical therapy or renal artery … • There is weak evidence suggesting similar rates of cardiovascular events between interventions; however … , it is likely that the studies were too small to detect different rates of cardiovascular events … • The evidence does not adequately assess comparisons of adverse events between medical treatment

292. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
     July 01, 2011 - events. … All interventions have the potential for adverse events. … Generally about 5-15% of CPAP vs. control patients in trials had specific adverse events they considered … Long-term adverse events included speech or voice changes, difficulties swallowing, airway stenosis, … In smaller studies, when these adverse events were reported they occurred in about 2–15% of patients

293. Improving Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
     December 01, 2019 - antibiotic prescribing compared with usual care that also had low-strength evidence of not causing adverse … to 72% overall prescribing reduction; similar continuing symptoms, limited activity, missing work, adverse … events or lack of efficacy, treatment failure, hospitalizations, and mortality); and electronic decision … Other interventions had evidence of improved or reduced prescribing, but evidence on adverse consequences … Other interventions also reduced prescribing, but evidence on adverse consequences was lacking, insufficient

294. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - reports, adverse events associated with discontinuation of treatment, and serious adverse events … • Withdrawals from study and discontinuation of treatment due to adverse events • All-cause mortality … events, discontinuation due to adverse events, and weight gain. … events Insufficient; no conclusions drawn Sertraline Sertraline + interpersonal psychotherapy Adverse … therapy Adverse events Insufficient; SSRI = selective serotonin reuptake inhibitor, TCA = tricyclic

295. Assessing Applicability (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
     January 01, 2009 - events. … events. … drug events, no response) Events rates markedly different than in community Event rates in treatment … events) was chosen. … events.

296. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - Peer Reviewer #3 Results (Pg 52) One reason for the low adverse events rate in the etanercept studies … are the active run-in periods that excluded children who had adverse events. … During the double-blind phase (Period B), serious adverse events occurred in two patients in the placebo … Acute infusional adverse events were reported in one (2%) patient in the abatacept group and two (3% … The adverse events data from that study are included in the Appendix.

297. Interventions To Improve Care of Bereaved Persons | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/bereaved-persons/research
     March 01, 2025 - regarding participant experience, validity and diagnostic accuracy of the screening tool or approach, or adverse … events associated with the screening process. … Recently bereaved individuals face higher risks of adverse health outcomes, including increased risk … interventions on grief and depression symptoms, but more data are needed on the presence or absence of adverse … events.

298. Noninvasive Treatments for Low Back Pain: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
     November 01, 2016 - Pharmacological therapies are associated with increased risk of adverse events when compared with placebo … �» Examples of reported adverse effects included mild bleeding at needling sites with acupuncture, … events when compared with placebo (��� to ���) … Table 4: Adverse Effects of Interventions for Low Back Pain Table 3: Nonradicular Chronic Low Back Pain … addiction, overdose, and death Nonsteroidal anti-inflammatory drugs ��Cardiovascular thrombotic events

299. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
     October 07, 2011 - events. … The purpose of this section is to describe the potential adverse events that may be encountered in … With respect to adverse events, an important finding of ONTARGET is that combination therapy had higher … adverse event rates but no more benefit than a single drug. … The key questions 1 and 2 specifically examine cardiovascular events and adverse events between drug

300. Urinary-Incontinence-Treatment Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
     October 29, 2012 - events: 1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70 Any adverse … events [(n/N (%)] 1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70 Any adverse events: … -2.5 ± 3.0; p< 0.0001 Adverse events (dry mouth) (7.4%) vs. (2.8%); p<0062) Quality of life … events [(n/N (%)] 1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70 Any adverse events … -2.5 ± 3.0; p< 0.0001 Adverse events (dry mouth) (7.4%) vs. (2.8%); p<0062) Quality of life