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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - events ���
Subgroup of 1 RCT 2269 Age and race do not affect the efficacy of either drug ���
Prophylactic … �� Gastrointestinal symptoms, fatigue, and headache
�� Rare adverse effects include leukopenia, aplastic … effects include bone marrow suppression, aseptic meningitis, and dermatological adverse events
�� Serious … adverse effects include gastrointestinal perforations, ulcers, and increased risk of heart attack or … effects include cardiovascular thromboembolic events, hepatic failure, TEN, SJS, and DRESS
NSAIDs =
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
January 01, 2022 - Events Other Reported Outcomes Funding Source Risk of Bias
21087411 Bestard, 2011 Prospective cohort … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse … events: 4.65% (10/215) vs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
January 01, 2022 - Events Other Reported Outcomes Funding Source Risk of Bias
21087411 Bestard, 2011 Prospective cohort … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse … events: 4.65% (10/215) vs.
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effectivehealthcare-admin.ahrq.gov/products/vaccine-safety/research-protocol
December 01, 2020 - events, typically enrolling several hundred subjects. … What adverse events (AEs) are collected in clinical studies (phases I–IV) and in observational studies … Understanding the role of human variation in vaccine adverse events: the Clinical Immunization Safety … event
CTCAE = Common Terminology Criteria for Adverse Events
Hib = Haemophilus influenzae type b … Adverse events of interest, included in electronic search terms
Adverse event
Vaccine type
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
May 01, 2024 - • Evidence regarding adverse effects among individuals of any age, effectiveness
for children and … potentially beneficial alternative or adjunct to pharmacoprevention, which may
be associated with adverse … Adverse events were often not ascertained systematically, and the extent to which
behavioral interventions … are associated with any adverse events remains understudied
(though rarely reported), as was delivery … Adverse events are rarely reported, although this appears understudied.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/inguinal-hernia_research-protocol.pdf
August 15, 2011 - no
mesh
Outcomes Patient-oriented effectiveness outcomes and adverse events (see list of outcomes … Adverse events include any unintended effects such as chronic pain, infection, small bowel perforation … The following will always be considered
objective outcomes: adverse events, hospital
stay, office … This item will only be used for the following
outcomes: hernia recurrence, adverse events,
QOL, FCT … MCSDs for different
adverse events
If meta-analysis is deemed appropriate and possible for a given
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/surveillance-report-2-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - adverse events according to drug class? … Harms and Adverse Events
a. … adverse events according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events,
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - When lesinurad was combined with xanthine oxidase inhibitors,
commonly reported adverse events were … However, the experts warned that lesinurad uptake could be
limited by concern about adverse events, … adverse events, than patients given placebo. … Occurrence of adverse events, including serious events, was similar in patients
given baricitinib or … Adverse events/nonfatal serious adverse events rates were
78.1%/8.6% and 82.4%/12.9% in patients who
-
effectivehealthcare-admin.ahrq.gov/products/medicine-safety-call-center/research
November 01, 2017 - Abstract
Adverse drug events impose a large cost on the society in terms of lives and healthcare costs … In this paper, we propose an information technology architecture for enabling the monitoring of adverse … drug events in an outpatient setting as a part of the post marketing surveillance program. … on previous studies analyzing the involvement of community pharmacies in identifying and reporting adverse … drug events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
December 01, 2014 - When lesinurad
was combined with xanthine oxidase inhibitors, commonly reported adverse events were … However, they
warned, lesinurad uptake could be limited by adverse events, such as kidney complications … back pain,
nasopharyngitis, and upper respiratory tract infection.6 The most common adverse events … The experts warned that lesinurad uptake could be
limited by adverse events such as kidney complications … events, which could require additional adverse event monitoring
while patients are taking lesinurad
-
effectivehealthcare-admin.ahrq.gov/products/restless-legs/research
December 01, 2019 - assessed RLS symptom impact, sleep scale scores, disease-specific quality of life, withdrawals, and adverse … Dopamine agonists resulted in more patients who experienced at least one adverse event (high-strength … Treatment withdrawals were due to lack of efficacy (6% to 37%) as well as augmentation and other adverse … events. … Adverse effects of pharmacologic therapies and long-term treatment withdrawals due to adverse effects
-
effectivehealthcare-admin.ahrq.gov/products/head-neck-cancer-update/clinician
December 01, 2019 - This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … The present review assessed the comparative effectiveness and adverse effects of 3DCRT, IMRT, SBRT, and … Clinical Bottom Line
Summary of Key Findings and Strength of Evidence for the Benefits and Adverse … events (e.g., dysphagia) and improving quality of life
In understanding how outcomes are affected … events information
Assessing quality of life and other patient-reported outcomes with validated instruments
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Number 17
Effective
Health Care
2
cancer by the Gail model or other criteria and low risk
for adverse … events. … Use of
medications to
reduce risk of
breast cancer
Adverse effects
of medications
1, 3, 4
Women … events and ≤4 percent for
nonprotocol-specified events … Further research to more clearly identify
characteristics of individuals experiencing specific
adverse
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effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research-protocol
December 01, 2019 - Adverse events related to transfusions reported in included studies will be incorporated in the review … As noted in the previous report, transfusion-related adverse events are uncommon. … Adverse effects limited to thromboembolic events, hypertension, rash and similar symptoms, seizures, … rEPO antibodies, and transfusion adverse events.
… effect*” OR “adverse drug reaction*” OR “side effect*” OR “toxic effect*” OR “adverse event*” OR “complication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - to adverse events)? … events, withdrawal due to adverse events, renal
dysfunction, hepatotoxicity, QT interval, and bleeding … No withdrawals due to adverse events or other
adverse events were observed.59
Garlic
Four small short-term … events, bleeding, renal dysfunction,
hepatotoxicity, and serious adverse events). … events,42,73 renal dysfunction,42,73 serious adverse events,42
diarrhea,73 vomiting,73 nausea,73 adverse
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
September 01, 2016 - events by organ system.
2. … • Adverse event and deaths. … ClinicalTrials.gov began to mandate reporting of adverse
events in September 2009 as serious adverse … events and non-serious adverse events. … We
will compare the total adverse events reported in ClinicalTrials.gov compared with the
total reported
-
effectivehealthcare-admin.ahrq.gov/products/medication-therapy-management-1/research
May 01, 2019 - drug events) and real (adverse drug events being a subset of the drug related problems) drug related … Adverse Drug Events
The assessment of a medication therapy management program designed to impact adverse … We chose a validated research tool to assess adverse drug events. … The costs associated with adverse drug events among older adults in the ambulatory setting. … Risk factors for adverse drug events among older adults in the ambulatory setting.
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effectivehealthcare-admin.ahrq.gov/products/mhs4-opioid-stewardship/rapid-research
December 01, 2023 - interventions promote the appropriate use of prescribed and ordered opioids to reduce the risk of opioid adverse … events. … Drug Events Related to Anticoagulant Use in Adults
Rapid Evidence Product | Feb 1, 2024 … Product | Feb 9, 2024
Computerized Clinical Decision Support To Prevent Medication Errors and Adverse … Drug Events
View Collection
Related Product
Making Healthcare Safer IV collection
-
effectivehealthcare-admin.ahrq.gov/products/cancer-venous-thrombosis-anticoagulation/abstract
December 01, 2019 - Home
Evidence Reports
Anticoagulation for Venous Thromboembolic Events … Objective: To evaluate the outcomes of recurrent thrombosis, bleeding events, and survival for advanced … Project Timeline
Anticoagulation for Venous Thromboembolic Events in Patients with Cancer
Dec 15 … 2024
Alternative Payment Models
Rapid Evidence Product
Jan 16, 2024
Reducing Adverse … Drug Events Related to Anticoagulant Use in Adults
Systematic Review
Oct 12, 2020
-
effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research-protocol
December 01, 2019 - Secondary outcomes:
Health care utilization/economics
Quality-of-life measures
Adverse events … events: bowel obstruction, incisional hernia
RYGB-specific adverse events: anastomosis complications … (i.e., staple-line disruption or ulcer), nutritional deficiencies
LAGB-specific adverse events: band-related … events:
Short-term:
mortality
systemic medical complications (i.e. myocardial infarction … The evidence of risks (adverse events) will be summarized for each surgical procedure and nonsurgical