-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … 91% of the adverse
events. … from other adverse
clinical events under certain conditions. … They observe that the discrimination between adverse
drug events from other adverse clinical events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … events, particularly for new drugs or
other interventions.
40
The adverse events identified by … events annually, collects them into a database,
42
and issues information about adverse drug
events … for intolerable or severe adverse events. … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … events, particularly for new drugs or
other interventions.
40
The adverse events identified by … events annually, collects them into a database,
42
and issues information about adverse drug
events … for intolerable or severe adverse events. … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence is insufficient to draw conclusions about serious adverse
events. … Evidence was insufficient to draw conclusions about serious adverse events. … Evidence was insufficient to draw conclusions about
serious adverse events. … In general, adverse events of these drugs are mild and transient. … However, adverse events of newer
medications require further study.
-
effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/research
June 01, 2022 - Small to moderate, dose-dependent increases in withdrawal due to adverse events were found with SNRIs … Withdrawal from study due to adverse events was significantly increased with nonopioid drugs, with the … Large increases in risk of adverse events were seen with pregabalin (blurred vision, cognitive effects … Dose viii reductions reduced the risk of some adverse events with SNRI antidepressants. … Increased incidence of drug class–specific adverse events led to withdrawal from treatment in some patients
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - events
on costs. … The costs of adverse drug events
in hospitalized patients. … Adverse Drug Events Prevention Study Group.
JAMA. 1997;277:307–311.
21. … Adverse drug events in
hospitalized patients. … Using a hospital information
system to assess the effects of adverse drug events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - Events
high blood pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$ … Events
high blood pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$ … events
Response
Remission
No relapse
Efficacy
Sexual dysfunction
Other adverse … events
Disease
specific QoL
Adverse events
Serious adverse events
Adverse events
Prioritize … events
Rank 1 Outcome measure for psychiatrists
Rank 1 Outcome measure for patients
Danner,
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - • Opioids are probably associated with increased risk of short-term adverse events
versus nonopioid … events, nausea, dizziness, and somnolence,
but serious adverse events are uncommon in randomized trials … Opioids were associated with increased risk of short-term adverse events (any
adverse event, study withdrawal … due to adverse events, dizziness and nausea) for both
comparisons. … Serious adverse events were uncommon, but studies were not designed to
assess risk of overdose, opioid
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - events, withdrawals
because of adverse events, serious adverse events,
specific adverse events (including … of adverse
events. … events,
overall risk of serious adverse events, or discontinuation
due to adverse events. … events, overall
risk of serious adverse events, or discontinuation due to
adverse events. … events, or overall risk
of adverse events.
-
effectivehealthcare-admin.ahrq.gov/products/epilepsy-medicine/research
December 01, 2019 - The risk of withdrawing due to adverse events and the risk of several adverse events including fatigue … events and skin rash. … events. … The risk of certain adverse events including fatigue, somnolence, nausea, and alopecia were significantly … However, these adverse events did not significantly increase the risk of withdrawals.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - For medication-related adverse events,
three possible representations that could potentially be seen … A-3
Events of Interest Adverse events associated
with surgical and non-
surgical treatment
Defined … as treatment-related and systemic adverse events occurring ≤ 30 days after a surgical
procedure or … Events of Interest Adverse events associated
with medications
Medication-related adverse events, defined … Events of Interest Adverse events associated
with disease progression
Adverse events associated with
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - For medication-related adverse events,
three possible representations that could potentially be seen … A-3
Events of Interest Adverse events associated
with surgical and non-
surgical treatment
Defined … as treatment-related and systemic adverse events occurring ≤ 30 days after a surgical
procedure or … Events of Interest Adverse events associated
with medications
Medication-related adverse events, defined … Events of Interest Adverse events associated
with disease progression
Adverse events associated with
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - events, and specific adverse events if data were available
(e.g., injection-site reactions, infections … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in serious adverse events between
groups.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
January 01, 2011 - Events
Out-of-Pocket
Costs
Drug A
symptom relief
high blood
pressure
5 US$ … events
• Disease specific QoL . … events points to:
• Serious adverse events, which points to :
o Suicide and attempted suicide
o … Other serious adverse events
• Adverse events, which points to:
o Sexual dysfunction
o Other adverse … Events and Quality of life.
-
effectivehealthcare-admin.ahrq.gov/products/renal-update/research
January 01, 2020 - (RRT), other kidney events and function, hypertension events, blood pressure (BP), medication use, and … adverse events. … Procedural adverse events were rare but medication-related adverse events were not reported. … Clinically important adverse events related to PTRAS are rare; however, studies generally did not report … medication-related adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - Also, what are the risks of specific adverse events, the
frequency of events, and the certainty of the … Also important to
stakeholders is the severity of the adverse events, even when events are likely to … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting appraisal will assess whether adverse events, including serious adverse
events, were defined … for the presence or absence of specific adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - Also, ACEIs are associated with
well-known adverse events not shared by ARBs,
including cough (estimated … events,
withdrawals due to adverse events, serious adverse events reported,
withdrawal rates, and switch … For RCTs, this translates to a difference in rates
safety, adverse events, tolerability, to Moderate … There was no evidence of
differences in rates of other commonly reported specific
adverse events. … adverse events are
inconsistently reported.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - events from differing doses, modes of administration, and the
addition of opioids to the anesthetic … Events
Overall, adverse event rates were similar in both treated and control
groups, but studies were … Serious adverse events such as myocardial infarction, stroke,
and renal failure were either rarely reported … events of pain management
interventions used for elderly patients with hip fracture. … events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.