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Showing results for "adverse events".
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1441. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
      October 30, 2019 - Newly identified events in the RE-LY trial. … be included (number needed to treat to achieve a benefit or number needed to harm to achieve an adverse … Fatal GI bleeds were as follows: rivaroxaban 0.01 events per 100 patient years vs. … warfarin: 0.04 events per 100 patient years; p=0.15. … Transfusion ≥4 U were as follows: rivaroxaban 0.47 events per 100 patient years vs.

1442. Disposition of Comments Report for Comparative Effectiveness Review 128 Oral Mechanical Bowel Preparation for Colorectal Surgery (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
      April 30, 2014 - referring to complications that possibly could be avoided by OMBP whereas by "harms" you are referring to adverse … events that could be directly attributed to the prep (and not a failure of its efficacy). … anastomotic leak, abscess and peritonitis, because it was not clear in the reviewed studies whether events … Often RCTs do not explore all outcomes of interest, particularly adverse events.

1443. Chapter 10: Deciding Whether To Complement a Systematic Review of Medical Tests With Decision Modeling | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-decision-models/methods
      December 01, 2019 - identify the included patients. 20 Thus, when comparing various tests for diagnosing acute coronary events … falsely positive would receive no benefit but will still be exposed to the risk of treatment-related adverse … inhibitors (the treatment available at the time of the evidence report) The framework assumes no major adverse … report, the then-available treatment options (acetylcholinesterase inhibitors) do not have important adverse

1444. User Engagement, Training, and Support for Conducting N-of-1 Trials (Chapter 6) | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research
      August 01, 2019 - . 13 Finally, patients will learn which treatment or drug dose maximizes benefits while minimizing adverse … Specifically, patients may be worried about adverse drug interactions, possible suboptimal treatment … for Locally Advanced Gastric Adenocarcinoma Rapid Evidence Product Mar 06, 2024 Adverse … Events Associated With COVID-19 Pharmaceutical Treatments Page last

1445. Disposition of Comments for CER 162 Diagnosis of Celiac Disease (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/celiac-disease_disposition-comments.pdf
      January 28, 2016 - interpretation; 3) accuracy of diagnostic methods in select subsegments of the population; and 4) adverse … This is the inverse of the KQ4, the adverse effects of testing. … endoscopy and duodenal biopsy is beyond the scope of this small review, we have added a brief summary of adverse … events in the general population.

1446. The Evidence Base for Telehealth: Reassurance in the Face of Rapid Expansion During the COVID-19 Pandemic | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/telehealth-expansion/white-paper
      November 01, 2020 - One caveat is that only one study specifically addressed adverse events, reporting lower rates of complications

1447. Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
      August 01, 2012 - -There is indirect evidence to suggest that potential harms of monitoring include adverse effects from … We agree that chronic NSAID use and certain other drugs can have adverse renal effects, and that other … Page 3 please provide reference for CKD and frailty, as references are provided for all other adverse … The risk of cardiovascular events is higher in Hispanic versus non-Hispanic white adults with CKD. … Essentially, the risk of adverse cardiovascular events increases in proportion to the level of albuminuria

1448. Arthritis-Knee-Physical-Therapy Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
      November 01, 2012 - events were uncommon and varied across interventions. … Adverse events rates did not differ with statistical significance among treatment groups. … Adverse events were not severe enough to deter participants from continuing treatment. … – Adverse events were uncommon, varied across interventions, and included skin irritation with brace … Adverse events were not severe enough to deter participants from continuing treatment.

1449. Outcomes in COPD patients treated with theophylline (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
      December 01, 2009 - Patients were followed for events from April 1, 2003 to September 30, 2005. … Importantly, in several cases theophylline was associated with an increased risk of events; however, … measure medication adherence, and therefore do not know if the observed association is a result of adverse … An overriding concern is that the increased risk of events with theophylline may be a result of disease … It may simply represent an underestimate of events.

1450. Outcomes in COPD patients treated with theophylline (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
      December 01, 2009 - Patients were followed for events from April 1, 2003 to September 30, 2005. … Importantly, in several cases theophylline was associated with an increased risk of events; however, … measure medication adherence, and therefore do not know if the observed association is a result of adverse … An overriding concern is that the increased risk of events with theophylline may be a result of disease … It may simply represent an underestimate of events.

1451. Noninvasive Treatments for Low Back Pain | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/research-protocol
      December 01, 2019 - U.S. adults report recent (in the last three months) low back pain. 1,2 Low back pain can have major adverse … Global improvement Number of back pain episodes or time between episodes Patient satisfaction Adverse … Analytic Framework The analytic framework illustrates the population, interventions, outcomes, and adverse

1452. Mrsa-Screening-2010 Research-Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
      January 01, 2010 - eradicate/decolonize)—when compared to no screening—on MRSA transmission as measured by new acquisition events … O Adverse events: adverse effects of screening and treatment, including allergic reactions, nonallergic … Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus

1453. Defining an Optimal Format for Presenting Research Needs (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
      January 01, 2019 - and additional outcomes beyond monetary units (quality adjusted life expectancy, life expectancy, events … Lancet 20671013 Effect of calcium supplements on risk of myocardial infarction and cardiovascular events … meta-analysis 2008 BMJ 16679330 Systematic review and meta-analysis of ethnic differences in risks of adverse … glaucoma 1989 Graefes Arch Clin Exp Ophthalmol 2792592 Statistical uncertainty in the no-observed-adverse-effect … sensitivity analysis 1994 J Toxicol Environ Health 8187733 Statistical issues on the no-observed-adverse-effect

1454. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorder | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/disruptive-behavior-disorder/research-protocol
      December 01, 2019 - We added a separate Key Question for harms and adverse effects associated with interventions. … For Key Question 5, we will include studies that report harms (i.e., adverse effects) for an intervention … For Key Question 5, we will include adverse events and harms data (for interventions identified in Key … Potential adverse effects / harms of pharmacologic interventions include: Metabolic effects: weight … gain, hyperglycemia and diabetes, hyperlipidemia Extrapyramidal adverse effects: parkinsonism, acute

1455. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
      September 13, 2012 - duplex testing Treatment options See Figures 2–4 for possible interventions and comparisons Adverse … amoxicillin/clavulanate; dicloxacillin Inexpensive Usually require multiple doses/day; major adverse … events include rash, intolerance, allergy MRSA Clindamycin Also can treat anaerobes; allergy is … September 13, 2012 – Quality of life (general, disease-specific) – Mortality – Functional status o Adverse … events – For topical antibiotics contained in dressings: hypersensitivity, contact dermatitis, sensitization

1456. Cervical Degenerative Disease Treatment (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
      January 12, 2022 - dysphagia scales, return to work) • Fusion rate, reoperation rate • Harms (e.g., withdrawals due to adverse … events, serious adverse events, new symptomatic adjacent segment disease, postoperative infection … This may be based on sample size sufficiency and number of events.

1457. Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-1.pdf
      December 01, 2021 - When reported, the most common adverse events were discomfort, breathing difficulties, and skin events … but one trial found no difference between a P2 (N95 equivalent) respirator versus surgical mask in adverse … events in persons in the community.27 One trial reported no differences in harms between a surgical … were loss to followup Yes Yes Yes Good Chughtai A, 201616 Yes Unclear Unclear No No Yes For adverse

1458. Medicare-Medication-Use Research (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicare-medication-use_research.pdf
      April 01, 2014 - drug interactions.8,9 Multiple medications and use of psychotropic drugs increases the possibility of adverse … drug events.10, 11 Expenditures for medication coverage under Medicare Part D are substantial. … Ad- verse drug events in ambulatory care. New Engl J Med 2003;348:1556-64. 11. … Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive

1459. Patient and Provider Level Strategies to Address Racial/Ethnic Disparities in Health and Healthcare (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tech-brief-patient-provider-strategies-protocol-final.pdf
      May 18, 2022 - What are the reported unintended consequences, harms, or adverse events of the strategies used in studies

1460. Comparative Effectiveness of Screening for Methicillin-Resistant Staphylococcus aureus (MRSA) | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/mrsa-screening-2010/research-protocol
      December 01, 2019 - eradicate/decolonize)—when compared to no screening—on MRSA transmission as measured by new acquisition events … Adverse events: adverse effects of screening and treatment, including allergic reactions, nonallergic … Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus