-
effectivehealthcare-admin.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
January 01, 2012 - events, which would require its own expensive treatment
and followup. … events and avoiding drug interactions while
patients are taking HCV therapy. … One clinical expert stated that the ability to manage adverse events
will be a crucial factor determining … No
adverse events were reported from FMT.
125
FMT is being implemented in a limited number of research … Adverse events were similar in both trials and not
different among the treatments.
141
In another
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
November 08, 2011 - Our review will include an
assessment of adverse effects or harms associated with pressure ulcer treatment … treating a pressure
ulcer against another provide direct evidence of comparative effectiveness and adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
May 31, 2023 - stratifying
patients to 24 hours versus less time on magnesium may preclude
such a study, as the risk of an adverse … (early
diagnosis), continuity and continued follow-up of care, affordability
of care, medication adverse … that central pulse pressure was 50%
better than brachial pulse pressure in predicting cardiovascular
events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
March 29, 2016 - arbitrary
reference standards (e.g., 50% or 70% stenosis of a
coronary artery) when the risk of adverse … events bears a
continuous relationship with degree of obstruction. … It would also be useful to include the respective in
incidence of events so that the reader might be … aspect of the tests
included complications of the testing (e.g. renal failure,
allergic reactions, and adverse … , there is not an explicit statement that
vascular complications including stroke are included as
adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
June 01, 2013 - was weaned from PN support.31
The prescribing information states that the most commonly reported adverse … events occurring in
more than 10% of patients taking teduglutide were: abdominal distension, abdominal … events observed, although one expert representing a clinical perspective stated that decreasing PN … acceptance for teduglutide could be limited because of the need for
daily injections and potential adverse … events contrasted against the modest reductions in PN.
9
Health care delivery infrastructure
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
August 15, 2023 - events related to treatment*
Exclude:
• Neuroimaging (e.g., functional MRI)
Potential Effect Modifiers … , functional impairment, family
accommodation, quality of life, and acceptability of treatment and adverse … events related to
treatment. … and home/family domains
• Family accommodation
• Quality of life
• Acceptability of treatment
• Adverse … events related to treatment
Literature Search Strategies to Identify Relevant Studies to Answer
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
December 11, 2012 - Since the morbidity of liver-directed therapies is minimal and
rarely persistent, adverse effects of … This comment has been noted and the adverse
events for liver failure and biloma in the study by
Vogl … As our conclusion states
we believe the most important outcomes to be
overall survival, QOL and adverse … events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
January 01, 2012 - They also subject patients to
risks of adverse events, some of which could be serious.
-
effectivehealthcare-admin.ahrq.gov/products/breast-reconstruction-mastectomy/protocol
July 01, 2021 - delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)*
Thromboembolic events … delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)*
Thromboembolic events … delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)*
Thromboembolic events … OR "Tissue Transplantation"[Mesh] OR ((flap OR flaps) AND (surgical OR surgery)))
AND
(safe* or adverse … or risk or risks or reaction* or complication* or poison* OR side effect* or safety or unsafe OR ((adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/metanalysis-proportion-rate-comparison_research.pdf
November 01, 2013 - perform meta-
analyses of sensitivity and specificity to summarize medical test performance, or of adverse … or
harmful events. … For
example, one would use a meta-analysis of proportions to calculate the summary frequency of
adverse … or harmful events. … Depending on the clinical context, adverse events can be rare (e.g.,
the incidence rate of rhabdomyolysis
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
July 01, 2012 - identify the
included patients.20 Thus, when comparing various tests for diagnosing acute coronary events … falsely positive
would receive no benefit but will still be exposed to the risk of treatment-related adverse … inhibitors (the treatment available at the time of the evidence report)
The framework assumes no major adverse … report, the then-available treatment options (acetylcholinesterase inhibitors) do not have
important adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
July 01, 2023 - safety, increase reporting of outcomes,
or offer feedback to institutions to reduce patient safety events … assessing data
quality of a report card)
• No clear description of
comparator
Outcome Safety
• Adverse … events
Quality of care measures
(including morbidity and mortality)
Implementation
• Barriers
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - Disruptions can occur due to myriad reasons ranging
from the scarcity of raw materials,4 unforeseen events … delays in care which can result in sourcing inferior or
illegitimate products,10 increased risk of adverse … events, and increased costs.
-
effectivehealthcare-admin.ahrq.gov/products/mhs4-surgical-report-cards/protocol
September 01, 2023 - safety, increase reporting of outcomes, or offer feedback to institutions to reduce patient safety events … types (or assessing data quality of a report card) No clear description of comparator Outcome Safety Adverse … events Quality of care measures (including morbidity and mortality) Implementation Barriers and facilitators
-
effectivehealthcare-admin.ahrq.gov/products/medication-adherence-interventions/research-protocol
December 01, 2019 - maintenance goals, relapse prevention)
Facilitation (continuous professional support, dealing with adverse … Patient satisfaction
Health care utilization (including associated costs)
Quality of care
Adverse … events
Timing
All timing
Settings
Outpatient primary and specialty care settings will be included … utilization (and associated costs) for studies with a significant improvement in medication adherence
Adverse … events
Publication language
English
All other languages (due to limited
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - Earlier in document refer repeatedly to “adverse effects” –
change here to adverse effects instead of … “harms”
Revised and have replaced harms with adverse effects
throughout the report. … Maternal fever,
nausea, and vomiting are not a list of anesthesia-related
events. … “adverse effects” Have revised throughout the report. … We then systematically
reviewed each included study for adverse effects.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
May 01, 2013 - ROM† Harms Low 5 Harms and adverse events were infrequently
reported for WMC or ROM. … One of the studies reported few events,
providing imprecise results. … events for WMC
or ROM. … WMC is comparable to ROM with regard to low
frequency of harms, as no studies reported serious adverse … events or mortality.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
March 31, 2010 - Obese children and
adolescents are more likely to have adverse health conditions, such as cardiovascular … purchasing behaviors
o dietary intake
o food access
o physical activity
o sedentary behavior
Adverse … Analytic Framework for Comparative Effectiveness of Childhood Obesity Intervention Programs
Adverse … Psychosocial outcomes,
e.g., stigma
Impact on growth and
development
Injury
Cost
Other adverse … is a medical condition in which excess body fat has accumulated to the extent
that it may have an adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
July 21, 2014 - Key Question 7: What are the comparative adverse effects of various tests for diagnosis
Source: www.effectivehealthcare.ahrq.gov … Key Question 8: What are the comparative adverse effects of various treatments for non-
muscle-invasive … a) How do adverse effects of treatment vary by patient characteristics, such as age,
sex, ethnicity … 3, KQ 4, KQ 5: Progression of cancer
• For KQ 2, KQ 3, KQ 4, KQ 5: Quality of life
• For KQ 7: Adverse … diagnostic testing (e.g., false-positives, labeling,
anxiety, complications of cystoscopy)
• For KQ 8: Adverse
-
effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol
December 01, 2020 - Key Question 7
What are the comparative adverse effects of various tests for diagnosis and post-treatment … Key Question 8
What are the comparative adverse effects of various treatments for non-muscle-invasive … How do adverse effects of treatment vary by patient characteristics, such as age, sex, ethnicity, performance … , KQ 3, KQ 4, KQ 5: Progression of cancer
For KQ 2, KQ 3, KQ 4, KQ 5: Quality of life
For KQ 7: Adverse … diagnostic testing (e.g., false-positives, labeling, anxiety, complications of cystoscopy)
For KQ 8: Adverse