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effectivehealthcare-admin.ahrq.gov/products/behavioral-interventions-migraine-prevention/protocol
April 01, 2024 - Quality of Life (QOL) Migraine Specific: HIT-6, MSQoL v2.1, MSQ General: SF-36, EQ-5, SF-12, PedsQL Adverse … Migraine/Headache frequency, migraine-related disability, migraine-specific quality of life, and/or adverse … events. … reported in days per month or 28 days) Functional Status/Disability Quality of Life (Migraine specific) Adverse … intervals relative to a clinically important effect estimate, sufficiency of sample size, and number of events
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
June 15, 2016 - global assessment, patient satisfaction)
§ Surgery (i.e., rate of undergoing knee replacement)
o Adverse … We will include prospective
observational studies and case reports that report on adverse events … events, we will use the McHarms scale for
each study. … Adverse events identified in RCTs will be pooled if their numbers are reported separately by
treatment … Adverse events reported in single arm trials and observational studies will be
tabulated and reported
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effectivehealthcare-admin.ahrq.gov/products/alcohol-use-disorders/protocol
December 01, 2022 - KQ 3a : What adverse effects are associated with medications for adults with alcohol-use disorders in … effects of intervention(s)
withdrawals due to adverse events
nausea/vomiting
diarrhea
anorexia … and case-control studies comparing two or more of the medications of interest in which at least 50 events … and case-control studies comparing two or more of the medications of interest in which at least 50 events … For binary outcomes (e.g., adverse events), we will calculate risk differences between groups or risk
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effectivehealthcare-admin.ahrq.gov/products/dyspnea-advanced-cancer/protocol
June 01, 2020 - to dyspnea: hospitalizations, intensive care unit stays, emergency room visits
Patient-centered adverse … Studies with no events in both groups will be qualitatively summarized by providing information on the … confidence intervals for the proportion of events in each arm. 13
All meta-analyses will be conducted
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
September 06, 2016 - ages 5 and above
• Negative predictive for children ages 5 and above
KQ1 a-e:
• Any reported adverse … ages 5 and above
• Negative predictive for
children ages 5 and above
KQ1 a-e:
• Any reported adverse … the studies (i.e., risk of bias); precision (based on the size of the body of evidence,
number of events … NO chemical events in the human
airway during the immediate and late antigen-induced asthmatic response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s166.pdf
October 01, 2007 - wakefulness after
sleep onset (WASO), sleep efficiency (SE), total sleep time
(TST), sleep quality (SQ), and adverse … events (AE). … Adverse Events
The AE estimates were similar across comparisons,
ranging from risk differences of 0.07
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - Health and safety outcomes (e.g., cardiovascular events or incidence of work-
related injuries)
Source … o KQ 2d: Harms: Increased barriers to reporting work-related injuries or
illnesses, work stress, adverse … Framework
The analytic framework in Figure 1 illustrates the population, interventions, outcomes,
and adverse … Initiatives, National
Institutes of Health 2015 February 26, 2015. https://prevention.nih.gov/programs-
events
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effectivehealthcare-admin.ahrq.gov/products/worker-health/research-protocol
December 01, 2019 - interventions for improving the following outcomes:
Health and safety outcomes (e.g., cardiovascular events … outcomes
KQ 2d: Harms : Increased barriers to reporting work-related injuries or illnesses, work stress, adverse … Framework
The analytic framework in Figure 1 illustrates the population, interventions, outcomes, and adverse … https://prevention.nih.gov/programs-events/pathways-to-prevention . Accessed March 8, 2015.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
April 22, 2013 - Rare but serious adverse events are rarely captured
by RCTs.
1) We excluded very small studies (n< … Further, adverse effects of antipsychotic drugs
have been thoroughly summarized in existing
systematic … Conclusion Further, it is noted throughout the review that
intervention effects on overall CVD risk, CVD events … We have modified one gap to include better
reporting of adverse events and added an
additional research … Not all outcomes are explicitly listed in the KQs;
however, adverse effects and other outcomes
are
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effectivehealthcare-admin.ahrq.gov/products/monitoring-programs/protocol
August 01, 2024 - Disruptions can occur due to myriad reasons ranging from the scarcity of raw materials, 4 unforeseen events … delays in care which can result in sourcing inferior or illegitimate products, 10 increased risk of adverse … events, and increased costs.
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effectivehealthcare-admin.ahrq.gov/products/renal-cancer/clinician
December 01, 2019 - is a summary of a systematic review that evaluated the recent evidence regarding the benefits and adverse … study; RR = risk ratio; SOE = strength of evidence; WMD = weighted mean difference
a Harms refer to adverse … events directly related to the management strategy.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
September 01, 2019 - For outcomes that are not meta-analyzed, such as quality of life and adverse events,
the information … reported at a coarse
level in the systematic review, such as different definitions of cure or specific adverse … events
(e.g., by focusing on the corresponding part of the evidence base through a simple interface
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effectivehealthcare-admin.ahrq.gov/products/long-covid-models-care/protocol
June 01, 2023 - design/size Comparator if relevant Concurrent/prior treatments Length of follow-up Outcomes measured Adverse … events/harms/safety issues reported What are gaps in our understanding of long COVID models of care? … Supply Chain Disruption Monitoring Programs
Rapid Evidence Product
Mar 06, 2024
Adverse … Events Associated With COVID-19 Pharmaceutical Treatments
Rapid Evidence Product
Oct 28
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Adverse effects, including but not limited to effects of sedation or anesthesia
Timing:
Timeframe … Adverse effects, including but not limited to pain, infection, hematoma, and edema
Long-term (more … Adverse outcomes (harms) will also be captured and
discussed.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - treatment and followup duration or have
indeterminable numerators and denominators for outcomes and adverse … demographics, method of diagnosis, enrollment, and severity, descriptions and results of
primary outcomes and adverse … One can use case series, but they have
no controls and the rate of “adverse events” among placebo groups … Placebo--
efficacy and adverse effects in controlled
clinical trials.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
January 15, 2016 - Why are we mentioning imaging if you
are not discussing possible adverse events. … this
The 2 comparative studies addressing imaging that met criteria for the
review did not discuss adverse … vast majority of these retrospective studies, there
is no specific monitoring performed for potential adverse … Timolol studies, no harms were reported
but most of these did not do any specific
monitoring for adverse
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effectivehealthcare-admin.ahrq.gov/products/c-difficile-update/research-protocol
December 01, 2019 - treatment and followup duration or have indeterminable numerators and denominators for outcomes and adverse … demographics, method of diagnosis, enrollment, and severity, descriptions and results of primary outcomes and adverse … One can use case series, but they have no controls and the rate of “adverse events” among placebo groups … Placebo--efficacy and adverse effects in controlled clinical trials.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
January 01, 2012 - experienced an average reduction of the Clinical Colitis Activity Index
to 57% of baseline, and no adverse … events were seen during the 28-week followup period, the
authors reported.
9
In a larger study of … events. … Some experts were also unsure if reductions in PN
would be enough to outweigh adverse events observed … events contrasted
against the modest reductions in PN.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - Coalition in the United States is
an example of committed patients creating a registry of perceived adverse … events in order to
empower people to take control of their own medical treatments and safety.51 While … direct
attribution of these adverse events to medical errors may not be possible or appropriate, a … medical
events has on patients and their families”, and notes that other studies of medical errors, … A
patient-initiated voluntary online survey of
adverse medical events: the perspective of
696 injured
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/advanced-care-decision-aids_technical-brief.pdf
July 01, 2014 - proxy decisionmaker and offer some general values and
preferences or care goals for various potential events … likelihood of real benefits from different types of care and interventions and the probability of
adverse … events from treatment. … Were harms or adverse effects collected in the studies; what were they?
f. … Only those with
advanced illness or at high risk of catastrophic health events are encouraged to seek