-
effectivehealthcare-admin.ahrq.gov/products/trauma-informed-care/protocol
October 01, 2023 - Background and Objectives
Exposure to adverse and potentially traumatic experiences … more service, and 3) delivering point of care interventions to promote wellbeing and prevent future adverse … (e.g., domestic violence, human trafficking), natural disaster, trauma-processes, and other trauma events … available), clinical characteristics (e.g., presenting concerns), and results and timing of outcomes and adverse … Definition of Terms
Abbreviation
Definition
ACEs
Adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
March 01, 2011 - rosiglitazone, a thiazolidine-
dione, was found to be associated with
myocardial infarction, major adverse … cardiovascular events, mortality from
cardiovascular causes, and all-cause
mortality.8 A more recent … and pioglitazone uti-
lization from January 2007 through May 2008 associated with five risk-warning
events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
January 01, 2012 - events remain low. … surgical intervention, when compared with current surgical
management, and concerns over potential adverse … events associated with in utero surgery for repair of
myelomeningocele. … Based on potential reduction in VP shunt malfunction,
reduction in adverse events, and improvement … events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
January 01, 2011 - Effect Methods Group57
and other experts.58,59
Adverse Effects/Harms
A search for adverse effects … DISEASES/ci
Drug terms AND Exp LIVER
DISEASE/si
subheadings linked to drug name Exp DRUG NAMEadverse events … ,
po, to
Exp DRUG NAMEadverse events, to
floating subheadings Drug terms AND (ae OR po OR to
OR … (effect or effects
or reaction or reactions or event or
events or outcome or outcomse)])
Drug terms … adj2 (effect or effects
or reaction or reactions or event or
events or outcome or outcomse)])
indexing
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/insomnia_protocol-140716.pdf
April 03, 2014 - 28; Sickness Impact Profile Scale28;
World Health Organization Quality of Life (WHOQOL)28]
KQ2
Adverse … Any serious adverse effects (e.g., dependence, falls, abnormal sleep
behaviors, etc.) … Figure 1 provides an analytic framework to illustrate the population, interventions,
outcomes, and adverse … Sleep
&
Distress/Daytime
functioning
Secondary
Outcomes
Mood/well-being
Quality of Life Adverse … insomnia definition, method of diagnosis, and severity, descriptions and results of
primary outcomes and adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/insomnia_research-protocol.pdf
April 03, 2014 - 28; Sickness Impact Profile Scale28;
World Health Organization Quality of Life (WHOQOL)28]
KQ2
Adverse … Any serious adverse effects (e.g., dependence, falls, abnormal sleep
behaviors, etc.) … Figure 1 provides an analytic framework to illustrate the population, interventions,
outcomes, and adverse … Adults with
insomnia
disorder
subgroups:
elderly, adults
with prevalent
comorbidities
Adverse … insomnia definition, method of diagnosis, and severity, descriptions and results of
primary outcomes and adverse
-
effectivehealthcare-admin.ahrq.gov/products/glaucoma-treatment/research-protocol
December 01, 2019 - patient-reported outcomes, intraocular pressure, visual field loss, optic nerve damage, and harms and adverse … Outcomes for Key Question 6:
The proportion of participants experiencing the following adverse events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - brachytherapy (103Pd) implant
found no significant differences in the number of
biochemical failure events … Adverse effects were reported, but definitions and
severity varied widely. … • Distant metastases: No significant difference in distant failure
events between groups at the median … Biochemical/clinical progression or recurrence: No difference in
6.5 weeks) compared with PSA relapse events … significant
of different regimens differences between 20 Gy and 44 Gy in the number of
biochemical failure events
-
effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research-protocol
December 01, 2019 - Key Question 2
What adverse effects are associated with specific treatments for adults with fecal incontinence … coping behaviors relative to FI management
Social activity
Sexual function
Key Question 2 (Adverse … Other adverse effect(s) related to treatment (skin breakdown, urinary tract infection, etc.) … identified in the key questions, or have indeterminate numerators and denominators for outcomes and adverse … fecal incontinence diagnostic and severity criteria, descriptions and results of primary outcomes and adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
January 01, 2012 - They also subject patients to
risks of adverse events, some of which could be serious.
-
effectivehealthcare-admin.ahrq.gov/products/hro/protocol
August 01, 2024 - reliability; they anticipate, early detect, and respond to unsafe conditions before they result in adverse … events. 4 Respectful interaction and heedful interrelating are critical elements, as they foster trust
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
September 25, 2024 - PHQ-A, PI-ED), diagnosis (KQs 2 and 3 only), and
remission and response (KQs 1 and 3)
• Any reported adverse … events or unintended negative
consequences attributed to treatment
Additional outcomes (children … :
• Quality of life
• General and social functioning
• Disability
• Depression
• Anxiety
• Adverse … events
We will grade the SOE based on the recommendations given in the EPC Methods Guide.42 The … intervals relative to a clinically important effect
estimate, sufficiency of sample size, and number of events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/ped-mindfulness-protocol-amended.pdf
September 25, 2024 - PHQ-A, PI-ED), diagnosis (KQs 2 and 3 only), and
remission and response (KQs 1 and 3)
• Any reported adverse … events or unintended negative
consequences attributed to treatment
Additional outcomes (children … of life
• General and social functioning
• Disability
• Depression
9
• Anxiety
• Adverse … events
We will grade the SOE based on the recommendations given in the EPC Methods Guide.42 The … intervals relative to a clinically important effect
estimate, sufficiency of sample size, and number of events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
February 05, 2025 - PHQ-A, PI-ED), diagnosis (KQs 2 and 3 only), and
remission and response (KQs 1 and 3)
• Any reported adverse … events or unintended negative
consequences attributed to treatment
Additional outcomes (children … :
• Quality of life
• General and social functioning
• Disability
• Depression
• Anxiety
• Adverse … events
We will grade the SOE based on the recommendations given in the EPC Methods Guide.42 The … intervals relative to a clinically important effect
estimate, sufficiency of sample size, and number of events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
December 09, 2009 - Objectives for the Systematic Review
Traumatic brain injury (TBI) occurs when external force from events … Framework
Provide an analytic framework to illustrate the population, interventions, outcomes, and adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
January 01, 2023 - reliability; they anticipate, early
detect, and respond to unsafe conditions before they result in adverse … events.4
Respectful interaction and heedful interrelating are critical elements, as they foster trust
-
effectivehealthcare-admin.ahrq.gov/products/skin-lesions-evaluation/research-protocol
December 01, 2019 - the test in patient management
Setting where the technique/modality was used
Outcomes assessed
Adverse … events, harms and safety issues reported
Comparators used (applicable only to comparative studies)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
September 01, 2011 - It also found strong evidence
that atypicals are associated with increased risk of
adverse events such … between
the increased risk of death and antipsychotics drugs, and
comparison of the development of adverse … New or increased adverse effects of off-label
indications have been observed and new atypicals
(asenapine … Table C compares the most important findings
regarding adverse events, by age group and study
design. … of the adverse event.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-machine-learning-screening.pdf
November 01, 2019 - effects and major
adverse effects, adverse
effects limiting treatment,
specific adverse events, … persistence and
reversibility of adverse
effects
Outpatient admissions,
inpatient length of stay … change in clinical score,
oxygen saturation,
respiratory rate, heart
rate, pulmonary function,
adverse … events,
escalation of care, length
of illness, duration of
oxygen therapy
Benefits (e.g., mortality … ,
adverse consequences of
poor vision), harms (e.g.,
serious adverse events),
implementation factors
-
effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research-protocol
December 01, 2019 - a larger amount of information would enhance safety for surgical patients and reduce liability for adverse … events. 2 During the past three decades, routine preoperative testing has been challenged by several … Two examples of such an analysis would be (1) a study that found no perioperative cardiac events and … management (other than procedure delay or cancellation)
Key Question 2:
Clinical outcomes (adverse … events)
Unnecessary/inappropriate procedure or anesthesia delays (based on an adjudication decision