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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
December 23, 2023 - Adverse Events Associated with COVID-19 Pharmaceutical Treatments
Evidence-based Practice Center … Rapid Review Protocol
Project Title: Adverse Events Associated with COVID-19 Pharmaceutical
Treatments … of adverse events
associated with the interventions, regardless of medical indication. … events
Common Terminology Criteria for Adverse Events (CTCAE) severity
category3
CTCAE event … Common Terminology Criteria for
Adverse Events (CTCAE) Version 5. November 27, 2017.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Events levels in reporting
adverse events. … Adverse Events More Than 45 Days
One RCT that reported at 14 days also reported serious adverse events … adverse
events. … adverse
events;55 risk of bias for adverse events collection and reporting was low. … Events 45 Days or Less
Adverse Events More Than 45 Days
Antivirals: Remdesivir
Adverse Events 45
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effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/research
September 01, 2023 - Key Question
KQ1: What are the serious adverse effects or events directly caused … KQ1a: In what timeframe are the adverse effects or events noted in KQ1 expected to occur (considering … of adverse events associated with the interventions, regardless of medical indication. … events Common Terminology Criteria for Adverse Events (CTCAE) severity category 3 CTCAE event name Timing … Common Terminology Criteria for Adverse Events (CTCAE) Version 5 . November 27, 2017.
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effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/rapid-research
March 01, 2024 - Serious adverse events, tocilizumab Serious Adverse Event Study n/N Intervention n/N Control Dose Risk … events in its absence, in particular when adverse events are nonspecific. … Serious Adverse Events The rapid review was limited to serious adverse events as defined in US statute … Most studies used the Common Terminology Criteria for Adverse Events levels in reporting adverse events … Common Terminology Criteria for Adverse Events (CTCAE) Version 5 . November 27, 2017.
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effectivehealthcare-admin.ahrq.gov/products/depression-harms/research
May 01, 2020 - Comparing SSRIs to each other or SSRIs to SNRIs showed statistically similar rates of adverse events … SSRIs (paroxetine, citalopram, sertraline) had fewer withdrawals due to adverse events than tricyclic … Vortioxetine had fewer adverse events than with duloxetine (high SOE, NNT 6). … Increasing age was associated with greater incidence of serious adverse events with escitalopram (low … events compared with placebo, while adverse events were statistically similar to placebo with SSRIs
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effectivehealthcare-admin.ahrq.gov/products/high-risk-drugs/rapid-research
January 01, 2024 - SHARE:
Reducing Adverse Drug Events Related to Anticoagulant Use … Most telemedicine interventions to prevent adverse events of anticoagulation in the ambulatory setting … The evidence was inconclusive about the effect of education and remote monitoring on adverse events in … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults. Rapid Response. … Project Timeline
Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse Drug Events
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - adverse events of
antidepressants. … Insufficient evidence:
mortality, serious adverse
events, withdrawals due to
adverse events
SSRI … placebo (RCT)
Adverse events
Similar with bupropion XR
(++)23
Serious adverse events
Similar with … placebo (RCT)
Adverse events
Similar with vortioxetine
(+++)25
Serious adverse events
Similar with … events and
comparative adverse events of antidepressants
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effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/research
January 01, 2022 - Signals from the prior report remain unchanged for adverse events that include anaphylaxis in adults … There remains insufficient evidence to draw conclusions about some rare potential adverse events. … The systematic review was supported by a Technical Expert Panel that identified key adverse events of … We documented observed rates and assessed the relative risks for key adverse events. … A large body of evidence is available to evaluate adverse events following vaccination.
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effectivehealthcare-admin.ahrq.gov/health-topics/adverse-effects
July 06, 2023 - S
T
U
V
W
X
Y
Z
Health Topics
Adverse … Products
Rapid Evidence Product July 6, 2023
Efficacy of Dental Services for Reducing Adverse … Events in Those Undergoing Insertion of Implantable Cardiovascular Devices
Rapid Evidence … Product July 6, 2023
Efficacy of Dental Services for Reducing Adverse Events in Those Receiving … Treatments of Major Depression in Older Adults
Research Protocol February 7, 2018
Adverse
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effectivehealthcare-admin.ahrq.gov/products/mhs4-computerized-cds/rapid-research
February 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events … drug events (low strength of evidence). … Overall, CDSSs reduce medication errors and adverse drug events, with moderate- and low-certainty evidence … Drug Events. … Drug Events.
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effectivehealthcare-admin.ahrq.gov/products/cardio-dental/research
July 01, 2023 - Events in Those Undergoing Insertion of Implantable Cardiovascular Devices … Events in Those Undergoing Insertion of Implantable Cardiovascular Devices … Efficacy of Dental Services for Reducing Adverse Events in Those Undergoing Insertion of Implantable … Project Timeline
Efficacy of Dental Services for Reducing Adverse Events in Those Undergoing Insertion … Events in Those Undergoing Insertion of Implantable Cardiovascular Devices.
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effectivehealthcare-admin.ahrq.gov/products/chemotherapy-dental/research
July 01, 2023 - Events in Those Receiving Chemotherapy for Cancer … SHARE:
Efficacy of Dental Services for Reducing Adverse Events … Efficacy of Dental Services for Reducing Adverse Events in Those Receiving Chemotherapy for Cancer. … Project Timeline
Efficacy of Dental Services for Reducing Adverse Events in Those Receiving Chemotherapy … Events in Those Receiving Chemotherapy for Cancer.
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effectivehealthcare-admin.ahrq.gov/products/high-risk-drugs/protocol
September 01, 2023 - The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … Action Plan) identified anticoagulants as a leading cause of adverse drug events. 9 For example, between … MHS II 10 expanded this scope to include interventions aimed at reducing adverse events linked to intravenous … US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. … Project Timeline
Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse Drug Events
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - There continues to be no evidence of
increased risk of adverse events for vaccines currently recommended … • There remains insufficient evidence to draw conclusions about some rare potential
adverse events … events
Red circle indicates evidence of risk of specific adverse events
White box indicates insufficient … events
Red circle indicates evidence of risk of specific adverse events
White box indicates insufficient … events
Red circle indicates evidence of risk of specific adverse events
White box indicates insufficient
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
May 01, 2020 - events; they may also include common adverse events and other specific adverse events important to clinicians … intolerable or severe adverse events. … Nonetheless, withdrawals due to adverse events are often reported even when serious or severe adverse … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … adverse events).
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effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
January 01, 2021 - Also, what are the risks of specific adverse events, the frequency of events, and the certainty of the … Also important to stakeholders is the severity of the adverse events, even when events are likely to … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting appraisal will assess whether adverse events, including serious adverse events, were defined … for the presence or absence of specific adverse events.
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effectivehealthcare-admin.ahrq.gov/products/treatments-acute-pain/research
August 01, 2022 - Opioids are probably associated with increased risk of short-term adverse events versus nonopioid pharmacologic … therapy for acute pain, including any adverse event, study withdrawal due to adverse events, nausea, … dizziness, and somnolence, but serious adverse events are uncommon in randomized trials. … Opioids were associated with increased risk of short-term adverse events versus NSAIDs or acetaminophen … Serious adverse events were uncommon for all interventions, but studies were not designed to assess risk
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effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/clinician
December 01, 2019 - events of pain management interventions used for elderly patients with hip fracture. … events. … [evidence insufficient]
Adverse Events
Overall, adverse event rates were similar in both treated … Serious adverse events such as myocardial infarction, stroke, and renal failure were either rarely reported … There is limited evidence about the benefits and adverse events of pain-control interventions when they
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effectivehealthcare-admin.ahrq.gov/products/mhs4-computerized-cds/protocol
September 01, 2023 - related to a drug." 1 , 2 Adverse drug events are a leading type of healthcare-related harm, accounting … for 39% of all adverse events in the inpatient setting. 3 Of these events, it is estimated that 27% … opportunity to reduce the frequency and severity of adverse drug events and improve patient outcomes … Medication Errors and Adverse Drug Events . September 7, 2019. Accessed on May 8, 2023. … Adverse drug events in ambulatory care.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … 91% of the adverse
events. … from other adverse
clinical events under certain conditions. … They observe that the discrimination between adverse
drug events from other adverse clinical events