-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
January 01, 2024 - Only one of the six studies (a nonrandomized study)
found evidence of a benefit on any adverse event … effects (e.g., bleeding).6,7 The 2014 National Action Plan for Adverse Drug Event
Prevention (ADE … event rates related to anticoagulation. … Advancing
medication safety: establishing a national
action plan for adverse drug event prevention. … Adverse event rates associated with oral
anticoagulant treatment early versus later after
hospital
-
effectivehealthcare.ahrq.gov/products/COVID-19-pharmaceutical-treatments/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - stroke (hemorrhagic, ischemic, or
unspecified), transient ischemic attack, unspecified
cerebrovascular event … one adverse event,
elevated serum aspartate transaminase (AST) and/or
alanine transaminase (ALT) above … Overall, 5 percent of
participants had an event. … Compared with statin monotherapy, more participants
developed at least one adverse event with statin-BAS … Nevertheless, all-cause mortality was a rare event
across most trials.
Followup duration.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
October 07, 2011 - In
the studies that did report episodes of angioedema, this adverse
event was observed only in patients … event data
bases (E.G., the FDA AERs database) for information on
angioedema. … Conceivably, information from adverse event databases
would support the clinical impression that the … Aside from the risk itself, the emergence of a new
adverse event from an outside meta-analysis raises … adverse event rates but no more
benefit than a single drug.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - There may be no increase in risk of serious adverse events (strength of evidence
[SOE]: low) or withdrawal … due to adverse events. … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive
deficits) and outcomes … Other prioritized adverse
events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … event; SOE = strength of
evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
May 29, 2025 - suited for testing hypotheses of whether one intervention is associated with a greater risk for an adverse … event than another and for quantifying that risk. … are well suited for testing hypotheses that one intervention is associated with a greater risk for an adverse … event than another and for quantifying that risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
May 29, 2025 - suited for testing hypotheses of whether one intervention is associated with a greater risk for an adverse … event than another and for quantifying that risk. … are well suited for testing hypotheses that one intervention is associated with a greater risk for an adverse … event than another and for quantifying that risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-table-e5.xlsx
January 01, 2025 - C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … C
Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … B
Total patients reporting treatment related adverse event: 21.1% (71/337) vs. 35.0% (118/337), RR 0.60 … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … event
U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
May 08, 2023 - What is the frequency and severity of medication errors and adverse drug events?
2. … drug
event after an encounter. … drug event rates
o Medication error rates
• Provider outcomes
o Changes in prescribing
behavior … Medication Errors and Adverse
Drug Events. … Adverse drug events in ambulatory care.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence is insufficient to draw conclusions about serious adverse
events. … Evidence was insufficient to draw conclusions about serious adverse events. … Evidence was insufficient to draw conclusions about
serious adverse events. … In general, adverse events of these drugs are mild and transient. … However, adverse events of newer
medications require further study.
-
effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
May 29, 2025 - Resolution of
diverticulitis, recurrent
diverticulitis,
avoidance of surgery,
morbidity, mortality,
adverse … events
Diagnostic accuracy,
adverse events
Occult colorectal cancer,
recurrent diverticulitis … ,
adverse events
Resolution of
diverticulitis,
morbidity, mortality,
adverse events
Recurrent … diverticulitis,
adverse events
Timing All All Acute vs. convalescent All All
Setting Inpatient,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - Low
Discontinuation rates and severe adverse events
higher with infliximab. … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in serious adverse events between
groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - events, withdrawals
because of adverse events, serious adverse events,
specific adverse events (including … because of
adverse events. … of adverse
events. … events, overall
risk of serious adverse events, or discontinuation due to
adverse events. … event rates for acupuncture than SGAs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - Clinical Event Outcomes, RCTs
No RCTs reported clinical event outcomes for comparisons
of total n-3 … Clinical Event Outcomes, RCTs
Regarding clinical event outcomes, one trial in an at
risk population … Clinical Event Outcomes, RCTs
No trial that reported clinical event outcomes evaluated
DHA alone. … Clinical Event Outcomes, RCTs
No trial that reported clinical event outcomes compared
marine oil FA … study arms, and no serious or
severe adverse event was attributed to n-3 FA.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
May 07, 2010 - event rates, overall adverse event
rates, and withdrawals due to adverse events, withdrawal rates, … events
•Withdrawals due to adverse events
•Serious adverse events reported
•Withdrawal rates
•Switch … Also, adverse
events (including, but not limited to, weight gain, impaired renal function, angioedema … events, withdrawals due to adverse events, serious adverse events
reported, withdrawal rates, switch … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - Also, ACEIs are associated with
well-known adverse events not shared by ARBs,
including cough (estimated … events,
withdrawals due to adverse events, serious adverse events reported,
withdrawal rates, and switch … This may reflect low event rates among
otherwise healthy patients and relatively few studies with
extended … For RCTs, this translates to a difference in rates
safety, adverse events, tolerability, to Moderate … There was no evidence of
differences in rates of other commonly reported specific
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-chemotherapy-dental.pdf
July 01, 2023 - Rapid Response: Efficacy of Dental Services for Reducing Adverse Events in Those Receiving Chemotherapy … In addition to being a
serious adverse event, mucositis also facilitates entry of oral bacteria into … However, it is a serious adverse event occurring in
some cancer patients, and early dental evaluation … event rates in patients with
cancer. … event rates and other relevant outcomes?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/high-cholestorol-medicines-update_research-protocol.pdf
December 31, 2013 - adherence as defined by the study investigator
SAEs as defined by the study investigator (e.g., an event … event; withdrawal due to an adverse
event; cancer; serum aspartate transaminase and/or alanine aminotransferase … event; withdrawal due to an
adverse event; cancer; serum AST
and/or serum ALT elevated ≥ 3 times … For sparse-data meta-analysis, we will employ the Peto odds ratio method when event
rates are less than … When between-event rates are between 5 to 10 percent,
substantial differences between the N of two arms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - In children with JIA, do the rate
and type of adverse events differ between:
a. … comparisons of the rate and type of adverse events
among the various DMARDs. … Recently published
studies of adverse event reporting databases provide
indirect evidence that suggests … • Reporting of adverse events. … A review of other
study designs revealed marked differences in the rate
and type of adverse event by
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - • In THR, LMWH has lower VTE and
adverse event risks than unfractionated
heparin; LMWH and aspirin … One NRCS had high risk of bias for adverse event
reporting and one was unclear. … Only about half of studies
reported major bleeding, the adverse event of greatest
concern for most … For VTE prophylaxis studies, there is a
fairly standard list of VTE and adverse event outcomes that … Larger RCTs should evaluate differences in treatment
and adverse event effects in relevant subgroups