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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-E-1-E-4.xlsx
January 01, 2023 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … With Any Adverse Event Intervention D, N of Any Adverse Event (Numberator Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
January 01, 2023 - C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … C
Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … B
Total patients reporting treatment related adverse event: 21.1% (71/337) vs. 35.0% (118/337), RR 0.60 … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
January 01, 2022 - C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … C
Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … B
Total patients reporting treatment related adverse event: 21.1% (71/337) vs. 35.0% (118/337), RR 0.60 … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - event; GDM = gestational diabetes mellitus
Pregnant women
≥24 weeks’ and
<24 weeks’
gestation … For each adverse event,
we will record the number of patients in each group and the number of patients … with an adverse
event. … We will count each event as if it corresponded to a unique individual. … assumption may overestimate the number of patients that experience an adverse event.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - Serious transfusion-related
adverse events are uncommon. … Hb Meta-analysis
increase >2 mg/dL (95% CI) not done1 3.42 (3.03, 3.86)2 3.36 (2.48, 4.56)
Pooled event … 950
Pooled relative risk (95% CI) 1.10 (0.93, 1.29)2 0.63 (0.59, 0.67)2 0.61 (0.52, 0.72)
Pooled event … 314
Pooled relative risk (95% CI) 0.86 (0.61, 1.21) 1.69 (1.36, 2.10) 1.44 (0.47, 4.43)3
Pooled event … patients treated with epoetin or darbepoetin
experienced a thromboembolic event, compared
with 4 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - Both successful
control of hypertension and effect on clinical event outcomes are important outcomes … )
No conclusions (rare event) for
patients without prior seizure
✓
No evidence of a difference … with prior
eclamptic seizure
Seizure
(preeclampsia with
severe features)
No conclusions (rare event … ) No conclusions (rare event)
Recurrent seizure
(eclampsia)
✓ ✓
Loading dose only MgSO4
regimens … yields shorter time to
start breastfeeding
No evidence
Infant morbidity No conclusions (rare event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - A total of 25 studies compared the adverse event
profiles of various SGAs. … event (moderate strength of evidence). … AE = adverse event; CI = confidence interval; EPS = extrapyramidal symptom; FGA = first-generation antipsychotic … Similarly,
few conclusions can be drawn regarding the comparison
of adverse event profiles across different … Some SGAs are associated with a better adverse-event
profile than other SGAs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Severity
information, particularly for the outcomes
of “any adverse event” and “withdrawal
due to … event
profiles.” … “The risk of any adverse
event…”was not different” instead of “were no different”. … event. … event.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - There were 84 studies
that reported at least one adverse event associated with
RFA. … event. … Atrioesophageal
fistula was reported in 26 studies: 5 studies reported 1
case each, with event rates … RFA monitoring and use modalities that are more
sensitive to asymptomatic recurrences of AF (e.g., event … All studies should actively
collect adverse event data from study participants.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
April 01, 2025 - event, although there were few serious adverse events
(SOE: Low) … Adverse effects/harms
--
Timing KQs 1-6. Any length of followup --
Setting KQs 1-6. … events compared with placebo and a small increase in the risk of
experiencing any adverse event versus … Medication use was
associated with an increased risk of experiencing any adverse event, but serious … adverse
events were infrequent and not different from placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
January 01, 2007 - Developing Indicators of Inpatient Adverse Drug
Events Through Non-Linear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the
Early Detection of Adverse Events. … Evaluation and Overview
of the National Electronic Injury Surveillance System- Cooperative Adverse … Drug Event
Surveillance Project (NEISS-CADES). … A Simulation-Based Evaluation of
Methods to Estimate the Impact of an Adverse Event on Hospital Length
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-e1-4.xlsx
January 01, 2024 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … With Any Adverse Event Intervention D, N of Any Adverse Event (Numerator) Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
-
effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
October 01, 2007 - Poisoning and
adverse event codes designed for the targeted ADEs had low
sensitivities and, when forced … These
fields included adverse event codes. … event codes. … drug event surveillance system. … Adverse drug event trigger tool: a
practical methodology for measuring medication related harm.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - and Epidural Anesthesia:
The evidence is insufficient to understand the effectiveness, benefits, or
adverse … for pain relief, but the data are too limited to draw
conclusions about the benefits or harms. ���
Adverse … Events
Overall, adverse event rates were similar in both treated and control
groups, but studies were … Serious adverse events such as myocardial infarction, stroke,
and renal failure were either rarely reported … For all modalities, the evidence is generally inadequate
to estimate harms and the incidence of adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - versus no event … being reciprocal for events and non-
events.
► Thus, if switching from event and non-event (e.g., from … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse … ► Risk difference is not the preferred measure when the event is rare. … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-e1-4.xlsx
January 01, 2025 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … With Any Adverse Event Intervention D, N of Any Adverse Event (Numerator) Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
January 01, 2024 - C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … C
Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … B
Total patients reporting treatment related adverse event: 21.1% (71/337) vs. 35.0% (118/337), RR 0.60 … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … event
U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - Effects] (374)
6 *DIFLUNISAL/ae [Adverse Effects] (27)
7 *ETODOLAC/ae [Adverse Effects] … (19)
8 *FENOPROFEN/ae [Adverse Effects] (41)
9 *FLURBIPROFEN/ae [Adverse Effects] (41)
10 … /ae [Adverse Effects] (109)
13 *KETOROLAC/ae [Adverse Effects] (16)
14 meclofenamate sodium.mp … /ae [Adverse Effects] (40)
11 *INDOMETHACIN/ae [Adverse Effects] (61)
12 *KETOPROFEN/ae [Adverse … Lumiracoxib compared less favorably with naproxen (0.37% event rate with lumiracoxib v 0.22%
event rate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
April 01, 2013 - Transfusion carries a
very low risk of infection and other adverse
events, including transfusion reactions … ,
alloimmunization, overtransfusion, and
immune modulation with theoretically
possible adverse effects … (For example, adverse events that could be
definitively attributed to transfusions were
not reported … in any trial included in this
review for adverse event outcomes.) … While it is possible that adverse event rates might be
somewhat different with lower baseline and target
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - effects to be considered, such as
distinguishing between treatment discontinuation due to adverse effects … effects
• Adverse effects of treatment (excluding clinical
outcomes listed above)
o Weight gain … The safety outcomes will be framed to help identify adverse events, including those
from drug therapies … event outcomes. … Definition of Terms
ACS Acute Coronary Syndrome
ACT Acceptance and commitment therapy
AE Adverse