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Showing results for "adverse event".
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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
    April 02, 2013 - KQ 4: We appreciate the reviewer’s query about whether this mortality is reasonably considered an adverseevent (AE) in reviewed interventions to prevent the development of PTSD symptoms. … This conceptualization of an adverse event is consistent with how AEs are defined in mental health … I suggest you might want to more clearly distinguish the source event(s) from the aftermath. … and PTSD; caused by the event and causing PTSD.)
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
    January 01, 2023 - Possible that different definitions (for adverse events) or scales (for quality of life) and different … Possible that different definitions (for adverse events) or scales (for quality of life) and different … Objective outcomes (e.g., survival, adverse events) were centrally assessed, reducing potential bias. … assessment, and no protocol or statistical analysis plan is available, but standard approach used to assess adverse
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
    April 21, 2015 - The proposed advantages over anticholinergics include potentially lower rates of adverse effects and … Also, adverse events may occur at any point after the treatment is initiated. IV. Methods A. … Update on AUA guideline on the review of efficacy and adverse effects. … ((adverse or undesirable or harm* or serious or toxic or negative) adj3 (effect* or reaction* or event … ((adverse or undesirable or harm* or serious or toxic or negative) adj3 (effect* or reaction* or event
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - In addition to effectiveness, decisionmakers need information on potential adverse risks, and special … Pain, function, pain relief satisfaction and quality of life, harms/adverse events (including withdrawal … predicting risk of opioid misuse, opioid use disorder, or overdose (KQ 1 h) Mitigation strategies Adverse … We will grade SOE for the two most critical health outcomes, pain, function, quality of life, and adverse … treatment patterns of prophylactic and acute migraine medications and incidence of opioid-related adverse
  5. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
    December 01, 2015 - adj2 (effect or effects or reaction or reactions or event or events or outcome or outcomes)).mp. ( … Found no difference in withdrawals due to adverse events. … 2 trials found no statistically significant difference in risk of any assessed adverse event. 24-week … No difference in risk of withdrawal due to adverse events. … event. not applicable to current practice. 24-week regimen of triple therapy with telaprevir (pegylated
  6. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
    December 01, 2015 - adj2 (effect or effects or reaction or reactions or event or events or outcome or outcomes)).mp. ( … Found no difference in withdrawals due to adverse events. … 2 trials found no statistically significant difference in risk of any assessed adverse event. 24-week … No difference in risk of withdrawal due to adverse events. … event. not applicable to current practice. 24-week regimen of triple therapy with telaprevir (pegylated
  7. effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
    December 29, 2020 - administration and study settings (e.g., home, outpatient, emergency room, and inpatient), lack of data on adverse … Evidence was insufficient to draw conclusions about serious adverse events.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
    January 15, 2015 - The risks and adverse events of the drugs are well-understood and include symptomatic hypotension, myalgia … What adverse events and complications have been associated with aggressive medical therapy or renal … lipid-lowering drugs) • Surgical repair Outcomes • Mortality, all cause • Kidney function o Event … therapy) o Categorical (eg, better/worse) o Continuous (ie, GFR, CrCl, SCr) • Blood pressure o Event … [Type text] [Type text] [Type text] • ≥6 months (except adverse
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
    January 01, 2023 - • Acute adverse events (AEs) were significantly fewer with PBI compared with WBI, with no apparent … This highlights the need to investigate outcomes of PBI among patients with adverse risk factors. … These advancements result in improved dose homogeneity that may lower the risk for adverse events. … PBI is associated with fewer acute adverse effects, but the risk of IBR among patients treated with … PBI who have adverse clinical or pathologic features is unclear.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
    September 30, 2010 - Thus, we will monitor all databases for adverse effects from significant risk devices. II. … Adverse events resulting from drugs. 2. … Adverse events resulting from nonpharmacological treatments. … rate - treatment group event rate). … rates multiplied by 1000: (control group event rate - treatment group event rate)*1000 We will
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
    April 01, 2013 - Adverse effects of psychotropic drugs (notably second-generation antipsychotics) also may contribute … effects, and adverse effects (KQs 1–4). … For adverse effects, we report significant worsening of psychiatric status and discontinuations due … to adverse effects. … For adverse effects, we considered discontinuation due to adverse effects and worsening of psychiatric
  12. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-asthma.pdf
    April 01, 2019 - Events of Interest Medication adverse events Adverse events related to asthma medications.
  13. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - However, experts noted that patients would likely be concerned about potential adverse events. … The researchers also reported that the most common adverse events “included headache (35%), nausea … The most commonly reported (≥10%) adverse reactions in patients treated…across all clinical studies … Of subjects receiving the recommended dose of 0.05 mg/kg/day, 88.3% (n=68/77) experienced an adverse … Many of these adverse reactions were reported in association with the underlying disease and/or use
  14. Menopause Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
    March 01, 2015 - What are the significant agent-specific harms/adverse effects of nonhormone therapies? … For the adverse events question, trials included in Key Question 1 that also reported adverse events … To place their magnitudes into context, with control-group event rates of 20 to 60 percent, SMDs can … Although the ORs exceed relative risks when placebo group event rates exceed 10 percent, they provide … The USPSTF review reported differences in event rates with estrogen/progestin or estrogen compared with
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
    April 01, 2013 - KQ 6 summarizes the evidence for the one trial that was identified that addressed adverse events. … Only two trials reported an incident that the authors classified as an adverse event. … Fewer children in TF-CBT experienced the adverse event of removal from treatment because of persistent … Typically, an intervention was based on an event (maltreatment or involvement with CPS), rather than … The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998 May;14(4):245-58.
  16. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - However, experts noted that patients would likely be concerned about potential adverse events. … The researchers also reported that the most common adverse events “included headache (35%), nausea … The most commonly reported (≥10%) adverse reactions in patients treated…across all clinical studies … Of subjects receiving the recommended dose of 0.05 mg/kg/day, 88.3% (n=68/77) experienced an adverse … Many of these adverse reactions were reported in association with the underlying disease and/or use
  17. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
    January 01, 2012 - Research indicates that individuals can reduce their risk of obesity-related adverse health conditions … While several experts mentioned the uncertainty of long-term adverse events as a potential barrier … The potential was tempered by experts’ significant concerns about reported adverse events. … However, multiple experts also noted the significant reported side effects and adverse events and the … discontinuation rate, which they believe to be significant adverse factors.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
    January 01, 2008 - the cost of treatment, the severity of diseases that HSCT is used to treat, and the prevalence of adverse
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
    January 01, 2009 - any commonly used dietary supplements decrease the effectiveness of these medications or increase adverse
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
    March 11, 2010 - possible association with increased miscarriage and neuropsychological complications in offspring, the adverse … • Adverse events i. Psychological or social impact of false positive screening tests. ii. … Adverse reactions are usually due to therapeutic overdosage and resulting hyperthyroidism. … (effect$ OR reaction$ OR event$ OR outcome$) [tiab] 10. 8 AND 9 11. 10 OR 7 OR 6 P Patient issues … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

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