Results

Total Results: 1,229 records

Showing results for "adverse event".
Users also searched for: patient safety indicators

361. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
     March 01, 2018 - event reporting (2 of 10 studies with posted results, 20%). … event and deaths. … ClinicalTrials.gov began to mandate reporting of adverse events in September 2009 as serious adverse … Event Reporting Rauck, 20129 NCT00643760 392 / 420 No difference Similar number withdrawn for adverse … event reporting (2 of 10 studies with posted results, 20%).

362. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
     January 01, 2024 - low density lipoprotein cholesterol (LDL-c) concentration, and between LDL-c concentration and CV event … and evidence-based guidance to optimize plasma lipoprotein profiles, with the goal of lowering CV event … Question 2 ● Cardiovascular events o Atherosclerotic cardiovascular disease (total) o Major adverse … We will aim for a minimum of about 10 observational studies for each specific intervention - CV event … TC – total cholesterol; Tg = Triglycerides/Triacylglycerols; apoA = apolipoprotein; MAC[C]E = Major adverse

363. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions … Synthesis We will summarize the primary literature by abstracting relevant continuous (e.g., age, event

364. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - • Outcomes: - Any reported harms/adverse events (AEs) that can be directly associated with use … , 6) 2º Outcome: Adverse effects of treatment Factors that affect Adherence/persistence with … KQ4 assesses the evidence for adverse effects of treatment. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0. … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

365. EHC Protocol: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
     September 24, 2024 - visits and hospitalizations, quality of life, missed school or work, preventive treatment- related adverse … events, imaging-related adverse events, serious adverse events, discontinuations due to adverse events … visits and hospitalizations, quality of life, missed school or work, preventive treatment-related adverse … events, imaging- related adverse events, serious adverse events, discontinuations due to adverse events … In the event of inclusion/exclusion conflicts between reviewers, we will adjudicate through discussion

366. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
     March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … Outcomes included adverse effects, intermediate outcomes, and final health outcomes. … KQ 4: In patients with cystic fibrosis, what is the frequency of nonmalignant serious adverse effects … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of

367. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - and evidence-based guidance to optimize plasma lipoprotein profiles, with the goal of lowering CV event … Question 2 ● Cardiovascular events o Atherosclerotic cardiovascular disease (total) o Major adverse … prospectively  We will aim for a minimum of about 10 observational studies for each specific PUFA - CV event … acids and cardiovascular disease (https://doi.org/10.23970/AHRQEPCERTA223), we included: for cardiac event … – total cholesterol; Tg = Triglycerides/Triacylglycerols; apoA = apolipoprotein; MAC[C]E = Major adverse

368. Acute Treatments for Episodic Migraine: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
     August 01, 2022 - No significant adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported. … No serious adverse events were observed. … No serious adverse events, death, and withdrawal due to adverse events were reported. … No patients reported adverse events.

369. Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
     November 01, 2023 - Collection of adverse events data was notably inconsistent across studies. … In particular, although some studies reported all adverse events, others only reported them in the situation … Trials of topiramate reported increased risks of many adverse events, including paresthesias, taste … For most serious harms, there was insufficient data to determine comparative rates of adverse events

370. Partial Breast Irradiation for Breast Cancer: Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
     August 09, 2021 - The review will also provide rates of adverse events of the various PBI modalities necessary for shared … In adult women with early stage breast cancer, what are the comparative effectiveness, adverse events … How do the effectiveness, adverse events, and cosmetic outcomes of partial breast irradiation vary by … In adult women with early stage breast cancer, what are the comparative effectiveness, adverse events … events (KQ1-2) Rate of adverse events (noncomparative series of PBI) (KQ 2a) Financial toxicity (KQ

371. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Our descriptive survey of adverse events associated with TT directly reflects KQ 3 "what adverse events … and adverse events (“a variety of adverse events” is not very specific, the authors should specify … adverse events). Edited to provide specific time frames for KQ 1. … event, overall. … adverse events rather than providing a Table only.

372. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Our descriptive survey of adverse events associated with TT directly reflects KQ 3 "what adverse events … and adverse events (“a variety of adverse events” is not very specific, the authors should specify … adverse events). Edited to provide specific time frames for KQ 1. … event, overall. … adverse events rather than providing a Table only.

373. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
     November 30, 2011 - dosages and durations of treatment according to various factors. 10 A common (50 to 60 percent) adverse … In addition, psychiatric, gastrointestinal, dermatological, and hematologic adverse effects underlie … effects of intervention(s)  Harms from antiviral treatment, including withdrawals due to adverse … events, serious adverse events such as severe neutropenia, psychological adverse events, flu-like … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

374. Nephropathy-Contrast-Induced Executive-2016 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
     January 01, 2016 - such as need for renal replacement therapy (including dialysis or hemofiltration), cardiac outcomes, adverse … Food and Drug Administration Adverse Event Reporting System (AERS). … data on cardiac outcomes, need for renal replacement therapy, mortality, length of hospital stay, adverse … For less frequent adverse outcomes, we used an optimum information size of 10,000, based on an expected … renal replacement therapy (5 studies), cardiovascular outcomes (7 studies), mortality (8 studies), adverse

375. Executive Summary_Systematic Review: Interventions To Improve Care of Bereaved Persons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
     March 01, 2025 - regarding participant experience, validity and diagnostic accuracy of the screening tool or approach, or adverse … 1.51; CI 0.86, 2.66) Insufficient Pharmacotherapy Loneliness N/A Insufficient Pharmacotherapy Adverse … systematic effect (RR 0.41; CI 0.01, 13.72) Low for benefit Expert-facilitated Support Group Adverse … Support Loneliness N/A Insufficient Peer Support Suicide outcomes N/A Insufficient Peer Support Adverse … more evidence is needed to quantify the presence and absence of unintended consequences, harms, and adverse

376. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - • Adverse effects of the interventions were inadequately reported in many studies. … All studies focused on benefits of physical activity, with inadequate reporting of adverse events in … activities, and intensity of physical activity; incomplete data analysis; inadequate reporting of adverse

377. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
     March 01, 2012 - renal insufficiency or development of dialysis dependence. 3 Impact of changing trends in outcome event … This may reflect low event rates among otherwise healthy patients and relatively few studies with extended … Although several studies collected data on angioedema, the event rates were very low or zero for all … In the four studies that did report episodes of angioedema, this adverse event was observed only in … Impact of changing trends in outcome event rates over time on the comparative effectiveness of ACEI,

378. Disposition of Comments for CER 178 Newer Medications for Lower Urinary Tract Symptoms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
     May 26, 2016 - To state that adverse event rates increase in cohort studies of an intervention implies that patients … cardiovascular adverse effects.. … Seventy-six percent of those patients were bothered by the adverse effect. … Key points refer only to adverse effects identified from RCT data; erections were not considered adverse … Peer Reviewer #3 Results -p. 23, lines 38-48 (long-term adverse effects).

379. Hemorrhage-Postpartum Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
     April 01, 2015 - Also, adverse events may occur at any point after the intervention is received. Figure A. … A fourth review noted more adverse effects related to misoprostol than placebo. … No serious adverse reactions were attributed to the study drugs in either RCT but reporting in 1 RCT … within a specific population with particular characteristics, there is an irreducible level of risk, and event … Therefore, it is sometimes hard to know whether to classify transfusion as an adverse outcome.

380. Vitamin-D-Calcium-Protocol-130611 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
     September 13, 2013 - stratify the findings of the previous review, as well as any newly included studies on efficacy and adverse … strength Source: www.effectivehealthcare.ahrq.gov Published online: June 10, 2013 4 o Adverse … mortality  Cancer and cancer-specific mortality  Renal outcomes  Soft tissue calcification  (Other) adverse … For upper limit (adverse event [AE]) outcomes, we will include any adverse effects of high intake in … Summary of Protocol Amendments   In  the  event  of  protocol  amendments,  the  date