-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - challenge and focus of current research is improving the natural history
of disease while minimizing adverse … to: (1)
induction of Crohn’s disease remission; (2) maintenance of Crohn’s disease remission; (3)
adverse … to: (1) induction of Crohn’s disease remission;
(2) maintenance of Crohn’s disease remission; (3) adverse … and
children with moderate-to-severe Crohn’s disease in terms of minimizing short- and long-term
adverse … and other cancers
• Infections
• Infusion and injection-site reactions
• Bone fractures
• Other adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - cardiovascular event; PASI = Psoriasis Area and
Severity Index; PGA = Physician’s Global Assessment … , differential loss to followup, overall
loss to followup, use of intention to treat, blinding of
event … confounding, baseline
differences, method to ascertain exposure, methods
to ascertain outcomes, blinding of event … Adverse events were not evaluated
in these studies. … cardiovascular event
MCS Mental Component Summary (part
of SF-36)
RCT randomized controlled
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - Also, adverse events may occur at any point after the treatment is received (e.g., medication
adverse … For the questions on safety and adverse effects, in addition to the above databases, we
will search … National Library of Medicine's TOXLINE® (1965 to present), and
Canada’s Adverse Drug Reaction Database … In the event the studies
cannot be pooled, evidence tables will be produced and bivariable statistical … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - experience, rate of operative delivery (including c-
section), maternal and child health outcomes including adverse … also address issues
around patient monitoring, nursing protocol, collaborative care, and potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
December 07, 2024 - events, serious adverse events
• Timing:
o No limitation on study duration or length of follow up … Serious Adverse Event Percent
3. Serious Adverse Event Detail
4. … Serious Adverse Events Numerator
5. Serious Adverse Events Denominator
6. … Withdrawal Due to Adverse Events Percent
7. Withdrawal Due to Adverse Events Detail
8. … Withdrawal Due to Adverse Events Numerator
9. Withdrawal Due to Adverse Events Denominator
10.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - and Laird
randomeffects model, except in instances where the
percentage of participants with an event … KQ 3: Adverse effects. … event and found a
significant difference in favor of metamizole (OR 3.50;
95% CI 1.04, 11.81; p = … KQ3: Adverse effects. No data were reported. … KQ 3: Adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - preventive practices for females of reproductive
8
potential and immediate drug discontinuation in event … Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Common adverse
events were headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-protocol.pdf
July 01, 2023 - scan
patient data for signs of clinical deterioration in order to alert a clinician of a potential adverse … systems that scan patient data for signs of clinical deterioration to
alert a clinician of a potential adverse … Activation of rapid response system (a process
measure)
• Cardiorespiratory arrest
• Serious adverse … Effectiveness of continuous or intermittent vital signs
monitoring in preventing adverse events on … scan patient data for signs of clinical deterioration in order to alert a clinician of a potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
January 01, 2011 - Effect Methods Group57
and other experts.58,59
Adverse Effects/Harms
A search for adverse effects … Archiving "event knowledge:"
bringing "dark data" to light. … Golder 2006 Adverse Effects
search approach MEDLINE EMBASE
specified adverse effects Drug terms AND … (effect or effects
or reaction or reactions or event or
events or outcome or outcomse)])
Drug terms … adj2 (effect or effects
or reaction or reactions or event or
events or outcome or outcomse)])
indexing
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
January 01, 2014 - services include providing education and counseling, improving medication adherence, and
detecting adverse … Populations
Medication misuse and poor medication adherence commonly contribute to adverse events … still
other MTM services relate to patient-centered outcomes (e.g., morbidity, mortality, reduced
adverse … transition in care, targeting highly activated
patients, targeting patients at time of high risk for event … event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
June 01, 2022 - traditional model across decades of
social networks, and may result in repercussions from management
should adverse … supportive
management, without which they expressed fears about repercussions from management
in the event … of a rare adverse event associated with maternity care.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - failure, coronary artery disease, and high
cholesterol)
o Patients with prior stroke (by type of event … review, as well as demographic and
other data needed for determining outcomes (intermediate, final, and adverse … The safety outcomes will be framed to help
identify adverse events, including those from drug therapies … study design; patient
characteristics; clinical settings; interventions; and intermediate, final, and adverse … event
outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - for Adverse Events (CTCAE) to ease in
their abstraction. … event reporting) … The McHarm tool is designed to directly assess the rigor of the adverse event assessment
(e.g., use … of a scale or checklist) and whether adverse event data were collected actively
(e.g., all participants … Common Terminology Criteria for
Adverse Events (CTCAE). Version 5.0. November 27, 2017.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
June 10, 2024 - for Adverse Events (CTCAE) to ease in
their abstraction. … event reporting) … The McHarm tool is designed to directly assess the rigor of the adverse event assessment
(e.g., use … of a scale or checklist) and whether adverse event data were collected actively
(e.g., all participants … Common Terminology Criteria for
Adverse Events (CTCAE). Version 5.0. November 27, 2017.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - Observational studies
were also included for rare adverse events. … Literature flow diagram
AE(s) = adverse event(s); KQ = Key Question; MA = meta-analysis; RCT(s) = randomized … • The most common adverse event associated with
allopurinol is a skin rash, occurring in up to 5 percent … The most commonly reported adverse
events in trials of febuxostat were abdominal pain,
diarrhea, and … FDA adverse event reporting system.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - However, both surgical and radiation treatments
result in significant short- and long-term adverse … Thus, all men who undergo treatment
risk suffering the adverse events of the treatment, while only … mortality, incidence of metastatic disease, quality
of life, morbidity from primary treatment, other adverse … Randomized controlled trials, nonrandomized comparative studies, and cohort
studies; for adverse events … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
August 31, 2017 - This is particularly a problem for rare
adverse events. … By including
observational studies, we capture a
better assessment of adverse
effects. … Peer Reviewer # 3
Methods Adverse event reporting. … For withdrawals, we reported overall
withdrawals and withdrawals due to
adverse events. … The adverse effects were minor for
the most part.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
June 24, 2014 - What adverse events and complications have been associated with
aggressive medical therapy or renal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - Adverse Events, All BCC Lesions
In Table B drugs were most likely to have adverse events
leading to … Events
Leading to
Discontinuation
(95% CI)
Serious
Adverse
Events (95%
CI)
Adverse
Events: … event; PDT=photodynamic therapy; SCCIS=squamous cell carcinoma in situ; NA=not applicable. … Adverse Events, All SCCIS Lesions
In Table C the highest mean frequency of adverse events
leading to … Adverse events
were inconsistently reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
April 01, 2020 - events, and no differences between comparison
groups in frequency of intervention-related
adverse … Table 64 in the full
report summarizes reported adverse events for
each intervention. … Evidence was low
or insufficient for other adverse events. … : A systematic
review of adverse event reports in randomized trials. … Acupuncture-related
adverse events: a systematic review of the Chinese
literature.