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Showing results for "adverse event".
Users also searched for: patient safety indicators

281. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - Impairments in performance Markers of inflammation Measures of intermediate outcomes (KQ 2) Adverse … Guide for Comparative Effectiveness Reviews34 and include published and unpublished evidence of the adverse … We define harms as a totality of all possible adverse consequences of an intervention.34 We will analyze … rate – treatment group event rate). … rates multiplied by 1000: (control group event rate – treatment group event rate)*1000.

282. Making Healthcare Safer IV Rapid Review: Examining the Impact of Implementing High-Reliability Organization Principles on Patient Safety Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-rapid-research.pdf
     May 01, 2025 - for safety and reliability; they anticipate, detect early, and respond to unsafe conditions before adverse … where staff were invited to learn about safety learning and improvement, discuss system root causes or adverse … Low-harm patient safety event reporting increased versus All VHA (p<0.001), but the serious safety event … PSOs can help providers develop successful approaches to improving quality and reducing adverse outcomes … High-Reliability Organization Principles labor and delivery (L&D) units, decrease maternal and neonatal adverse

283. Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
     March 01, 2024 - • The identified diagnostic studies did not assess the adverse effects of being labeled correctly … significant differences between stimulant and non-stimulant medications for most effectiveness outcomes and adverse … Furthermore, the identified studies did not assess the adverse effects of being labeled correctly or … effectiveness outcomes, such as ADHD symptoms (SMD 0.23; CI -0.03, 0.49; 7 studies, n=1611; low SoE) and adverse … Across studies, medication therapy evaluations reported more adverse events than non-medication interventions

284. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - larger infarcts, more significant left ventricular systolic dysfunction, and an increased risk of major adverse … Eligibility criteria, demographics Population Events rates markedly different than in the community Event … Term Definition ACS acute coronary syndrome EPC Evidence-based Practice Center MACE major adverse … cardiac event MBG myocardial blush grade PCI percutaneous coronary intervention RCT randomized controlled … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

285. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - effects and adverse effects that lead to treatment discontinuation.” … Pediatric safety trials should examine adverse effects at 12 months or more. … We added tables with dose response association with adverse drug effects in children. … We reviewed all evidence of adverse effects with drugs. … We analyzed specific safety outcome (specific adverse effects or treatment discontinuation due to adverse

286. Evidence Summary: Comparative Effectiveness Review No. 236 Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
     April 01, 2021 - • Although associations may exist between psychotropic medications and adverse events, causality … For child adverse outcomes, we found an association between benzodiazepine and neonatal intensive care … evidence available is consistent with some benefit; and (4) some studies suggested some increased adverse … underlying mental health disorder as the cause of the association, the causal link between the exposure and adverse

287. Noninvasive Treatments for Low Back Pain: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
     November 01, 2016 - Pharmacological therapies are associated with increased risk of adverse events when compared with placebo … �» Examples of reported adverse effects included mild bleeding at needling sites with acupuncture, … �» Although rates appeared to be low and there was no increased risk of serious adverse effects versus … in the report or to the drug labels of each drug for comprehensive information on their potential adverse … Table 4: Adverse Effects of Interventions for Low Back Pain Table 3: Nonradicular Chronic Low Back Pain

288. Type-2-Diabetes-Medications-Update Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
     December 31, 2013 - • For Key Question 3, conclusions regarding other adverse events are possibly out of date. … Metformin was associated with twice as many GI adverse event rates as were second- generation sulfonylureas … Adverse event rates were similar; hypoglycemic events occurred at a low frequency. 35 … Adverse event rates were comparable across treatment arms. … Do Not Know Metformin was associated with twice as many GI adverse event rates as were second-generation

289. Kidney-Disease-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
     October 01, 2012 - The conclusion is still valid but an additional study is available and the adverse event signals should … Adverse event signals should be followed up 8 Conclusions From CER Executive Summary RAND … Adverse event signals should be followed up In RCTs that compared different active treatments head … event signals should be followed up. … Relation between kidney function, proteinuria, and adverse outcomes.

290. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - , withdrawal due to adverse events)? … events o Serious adverse events (composite outcome)c o Neurologic adverse events (e.g., neuropathy … When event rates are <1 percent, the Peto odds ratio method will be used. … events (composite outcome—FDA definition of serious adverse events24), withdrawal due to adverse … What is a Serious Adverse Event? Updated December 15, 2010.

291. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
     September 29, 2011 - Patients may not be able to receive optimal medical therapy if they have allergies or adverse effects … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions … Synthesis We will summarize the primary literature by abstracting relevant continuous (e.g., age, event

292. Allergy-Seasonal Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
     July 01, 2013 - Adverse effects of nasal antihistamines may include a bitter aftertaste. … How do adverse effects vary with intermittent or continuous use? Key Question 3. … event was reported. … Three or more trials reporting the adverse event were required for pooling. … Harms assessment was limited by the absence of placebo groups, which can inform adverse event reporting

293. Colorectal-Cancer-Staging Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
     September 01, 2014 - used to address questions about harms and adverse events. … Six studies reported adverse events such as pain and minor rectal bleeding. … None of the included studies reported any adverse events related to CT or PET/CT. … For ERUS, the most common adverse event appears to be pain and minor bleeding; in theory, the major … adverse event of bowel perforation could occur, but no included studies reported such an event.

294. Atrial-Fibrillation-Ablation Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
     May 16, 2013 - There were 84 studies that reported at least one adverse event associated with RFA. … event. … Atrioesophageal fistula was reported in 26 studies: 5 studies reported 1 case each, with event rates … n=1; LA esophageal fistula n=1; death=1) Arrhythmogenic PVI: no serious adverse event Martinek … There  were  84  studies   that  reported  at  least  one  adverse  event   associated

295. Hepatitis-C Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
     November 01, 2012 - effects.23 Such adverse effects can be difficult to tolerate and can lead to premature discontinuation … However, serious adverse events were only reported in two trials,18,19 and the rate of serious adverse … adverse events with use of protease inhibitors, and the adverse events appear to be self-limited following … event. … There was no difference in risk of withdrawal due to adverse events.

296. Treatment Resistant Depression Surveillance FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
     April 01, 2016 - For reviewing adverse events (KQ 4), per our standard approach, we include observational studies. … (SOE: Insufficient) Specific adverse events. … We looked at both withdrawals that investigators attributed to adverse events and overall numbers … (SOE: Insufficient) Specific adverse events. … A single study with a small sample size indicated no difference in withdrawals due to adverse

297. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
     October 01, 2024 - relative to the number of patients, nursing care is more likely to be missed, which can result in adverse … Missed nursing care leads to higher mortality, lower patient satisfaction, and adverse events like … interest to leaders of healthcare organizations who must develop strategies for mitigating the adverse … Nurse staffing, missed care, quality of care and adverse events: A cross-sectional study. … low relative to the number of patients, nursing care is more likely to be missed, which can result in adverse

298. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
     November 27, 2012 - Please revise to reflect an accurate assessment of adverse event rates. … We have have made distinctions in our report regarding the adverse events for each drug. … Please revise to reflect an accurate assessment of adverse event rates. … Anemia rates were calculated based on clinician adverse event reports. … event.

299. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
     April 21, 2011 - continuous positive airway pressure (CPAP), associated with less morbidity, lower mortality, lower adverse … o Adverse effects of interventions (KQs 1–4): Rates of: – Aspiration – Secondary infections … The safety outcomes will be framed to help identify adverse events, including aspiration, secondary … events; and intermediate, final, and adverse events outcomes. … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

300. FRN 29: Future Research Needs on Procalcitonin-Guided Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
     August 01, 2014 - events of testing (pain, local bleeding, or infection) Adverse events of therapy (persistent … how adverse effects are defined, lack of details on types of adverse reactions) For pediatrics, … These should include fewer antibiotic adverse events and emergence of drug-resistant pathogens. … how adverse effects are defined, lack of details on types of adverse reactions) For pediatrics, … Vulnerable to antibiotic resistance and adverse effects of antibiotics.