-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - little to no difference in MBS (moderate COE) and may result
in little to no difference in serious adverse … infections, sexual function, urinary incontinence, physical signs of vulvovaginal
atrophy, common adverse … Infrequent adverse effects varied by treatment. … Er:YAG
hyperstack
NR NR NR Very lowa,f
⨁◯◯◯
Uncertain
NR NR NR N/A
Abbreviations: AE=adverse … event; BZA=bazedoxifene; CO2=carbon dioxide; COMMA=Core Outcomes in Menopause; DHEA=dehydroepiandrosterone
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - If they exhibit adverse effects, they were excluded from being randomized into the trial. … Since only patients tolerating therapy were randomized, the trial found a very low incidence of adverse … drug events, no response)
Events rates markedly different than in community Event rates in treatment … Next, compare the event rates in the treatment and control groups to community averages. … In both scenarios, there is a significant reduction in the odds of the event with therapy and no statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - Harms, Adverse events
a. Any adverse events
KQ 2, 5
7. … Depression event (diagnosis, recurrence, etc.)
9. Intermediate or Surrogate outcomes
a. … Harms, Adverse events
a. Any adverse events
KQ 6-7
• Adherence / Compliance
a. … events: No minimum duration
o Post-surgery: minimum 6 weeks (except adverse events)
• Prospective … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - As noted in the previous report, transfusion-related
adverse events are uncommon. … , rEPO antibodies, and
transfusion adverse events. … NOTE: No quality assessment of observational (adverse effects) studies will be
conducted.
E. … Time to event data, e.g., overall survival, will be calculated as hazard
ratios (HR) based on individual … effect*” OR “adverse drug reaction*” OR “side effect*” OR “toxic
effect*” OR “adverse event*” OR “complication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - patient and family perspectives can
be incorporated into patient safety, ultimately reducing risks for adverse … concurrent or historical
comparison group
• No clear description of
intervention
Outcome Safety
• Adverse … The missing evidence: a systematic review of patients' experiences
of adverse events in health care … Promoting engagement by patients and families to reduce adverse
events in acute care settings: a systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
January 01, 2007 - What adverse events and complications have
been associated with aggressive medical
therapy or renal artery … • The evidence does not adequately assess
comparisons of adverse events between medical
treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
March 29, 2013 - risk
of suicide, each of which compromises the health of both the woman and her fetus.5,6 Several
adverse … hepatoxicity, weight gain, metabolic syndrome, gastrointestinal symptoms,
and loss of libido)
• Overall adverse-event … there was important differential loss to followup or overall
high loss to followup; the adequacy of event … Maternal antidepressant use and adverse outcomes:
a cohort study of 228,876 pregnancies. … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
May 27, 2016 - event. … Peer reviewer #5 Background Why is dementia not a contributing event? … issues as defined in Patient Safety
Organization Privacy Protection Center
(PSOPPC) Common Formats for Event … drug
event prevention), impact of medication reconciliation, use of new
technologies that can increase … The focus should be on adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - Harms and Adverse Events
a. … event;
wk=weeks
*Newly included since the original 2020 systematic review. … event; wk=weeks
*Newly included since the original 2020 systematic review. … event; wk=weeks
*Newly included since the original 2020 systematic review. … event;
wk=weeks
*Newly included since the original 2020 systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - • Adverse events: These are specific to the interventions being examined (see Table
2). … In addition, adverse events may occur at
any point after the treatment is received. … • Case control studies are acceptable to assess for adverse events of DMARD treatment
(KQ3, KQ4) … Event Reporting System (AERS) from July 2008 to June 2009 for
adverse events related to JIA treatment … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - event [n (%)]: 187 (61.7) versus 149 (49.5); p=0.00318
No Signal
Oxybutynin chloride topical … events [(n/N (%)]
1 serious adverse events:
6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events: … event [n
(%)]:
187 (61.7) vs. 149 (49.5);
p=0.003
1 Signal
OTG vs. … events [(n/N (%)]
1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events … event [n (%)]:
187 (61.7) vs. 149 (49.5); p=0.003
Peter K.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … The systematic review
summarized herein assesses the effectiveness and adverse
consequences of possible … consequences associated with these tests either showed
an increase in some adverse outcomes or was … No evidence was found regarding the
effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - o Treatment discontinuation due to adverse effects. … www.effectivehealthcare.ahrq.gov
Published Online: November 3, 2011
The number needed to treat to achieve one event … avoided or excess events
(respectively) per population of 1,000 is the difference between the two event … Are migraineurs at increased risk of adverse drug
responses? … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - • Adverse events will be evaluated from studies of the drugs used for
osteoarthritis, rheumatoid … Also, adverse events may
occur at any point after the treatment is received.
IV. Methods
A. … We assumed that the adverse events occurred independently and
that the logarithm of the rate ratios … We also pooled clinical success rates and withdrawal due to adverse events from head-
to-head trials … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - Four of the seven
patients who received a
high-dose thiotepa-
based regimen are
event-free survivors … 1383
10/2009-
3/2018
Germany
FU: 6.5,
8.5 years
HSCT compared
with standard
chemotherapy
Event … chemotherapy with or
without peripheral
stem cell
transplantation,
radiation and/or
surgery
Event … Study
60
2/2008-2/2014
United States
FU: Not
reported
HDC, and HSCT
and/or radiotherapy
Event-free … Efficacy
Study
25
6/2009-
6/2014
United States
FU: 2 years
2 cycles of
HDCT/SCT
2-year Event-Free
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-disorders-imaging_disposition-comments.pdf
November 01, 2011 - The label of "Adverse event" for this column does not seem
appropriate- some are more patient limitations … event. … event. … Peer Reviewer 3 (Results)
Findings,
page 33, line
6
Adverse event needs to be defined and/or a different … vs. an adverse event related to the
safety of the device or procedure?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - 1.00 to 1.91)
Hospitalization 1 (12,098) SOE = High
No difference (RR 0.97; 95% CI 0.92 to 1.03)
Adverse … No differences in liver function or other
adverse events between therapies. … No differences in liver function or other
adverse events between therapies. … events 2 (18,423) SOE = Moderate
Adverse events occurred in almost equal proportions of
patients in … events 1 (5,599) SOE = Moderate
No differences in liver function or other adverse events
between
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - Research indicates that individuals can reduce their risk of obesity-related adverse health conditions … However, concerns over potential
adverse events associated with antiobesity pharmacotherapies have … Another expert with a research perspective expressed concern about adverse gastrointestinal events … The potential was tempered by experts’ significant concerns about adverse events
reported thus far. … discontinuation rate, which they believe to be significant adverse factors.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
June 01, 2010 - event signal detection and signal strengthening
• Safety surveillance data mining (hypothesis generation … value of diagnosis codes of interest in
automated health care data
• Potential to identify immediate adverse … event risk
1.4.4. … Potential additional issues include anti-trust policies
and intellectual property concerns in the event … Potential
population-based electronic data sources for rapid
pandemic influenza vaccine adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
June 01, 2017 - The adverse
event results were harder to correlate, because they were reported very differently in the … In general, there were few serious adverse events and many other
adverse events. … showed more adverse events in the intervention group. … events, including serious adverse events (not defined), other
adverse events (not defined), and acute … However, because these are time-to-event data, we would
need hazard ratios to perform a meta-analysis