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Showing results for "adverse event".
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201. Disposition of Comments for Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis -- Update of a 2007 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
     March 01, 2012 - event." … event." … For adverse event, test, and exploration (when there are enough number of studies) of heterogeneity … Amgen Results: Chapter 3 In pooling and interpreting the observed adverse event data from disparate … In an adverse event analysis of a clinical trial, the p-value is considered more as a “descriptive statistic

202. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
     January 01, 2011 - Outcome(s): Survival, quality of life, palliation, and safety/adverse events. 2. … recurrence post-transplantation, prevention of tumor progression while on transplant list, and safety/adverse … Outcome(s): Survival, quality of life, palliation, and safety/adverse events.

203. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
     October 01, 2010 - event, avoiding arbitrarily selected point estimates such as 4% and less in order to provide a better … Discussion Adverse effects: “There is a moderate level of evidence to show that adverse events associated … Most studies used multivariate logistic regression as opposed to time to event analysis in drawing their … Most studies reported hazard ratios, implying at least a time to event analysis, though granted studies … event.

204. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the increasing … Link H focuses on the adverse events of therapy. … events of testing (pain, local bleeding or infection) Adverse events of therapy (persistent or … The change in wording related to adverse events reflects the importance of possible harms resulting … , and antibiotic Adverse events of testing and therapy (e.g., persistent or recurrent infection

205. Appendixes A-D: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendices.pdf
     January 01, 2025 - events, imaging- related adverse events, serious adverse events, discontinuations due to adverse events … events) Yes (3 unpublished trials identified) At 8 weeks followup: Only 1 participant with event … Adverse events Insufficient12 Pharmacologic intervention Reloxaliase vs. … Placebo Adverse events Insufficient41 Serious adverse events Insufficient41 Pharmacologic intervention … AHA vs. placebo Adverse events Moderate17, 18 Serious adverse events Insufficient17 Combined dietary

206. Acute Treatment for Episodic Migraine: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
     June 01, 2022 - No serious adverse events were observed. … No serious adverse events were observed. … events RR: 1.10; 95% CI: 0.95 to 1.28; I² =N/A Serious adverse event RR: 0.75; 95% CI: 0.21 to 2.76 … events RR: 2.67; 95% CI: 2.07 to 3.44; I² =N/A Serious adverse event RR: 1.93; 95% CI: 0.36 to 10.41 … events RR: 2.42; 95% CI: 1.87 to 3.15; I² =N/A Serious adverse event RR: 2.56; 95% CI: 0.50 to 13.05

207. Radiotherapy Treatments for Head and Neck Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
     August 01, 2015 - The present review assessed the comparative effectiveness and adverse effects of 3DCRT, IMRT, SBRT, … This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … Summary of Key Findings and Strength of Evidence for the Benefits and Adverse Effects of Radiotherapy … 3DCRT, SBRT, and PBT: �– In achieving tumor control and improving patient survival �– In reducing adverse … risk of xerostomia might be reduced with the use of IMRT versus 3DCRT �� The potential long-term adverse

208. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - The Stein data can also be added to the section “Participants with at least one adverse event” in the … event…….” … event rate (Davidson MH, Robinson JG. … - On page D-68, participants experiencing an adverse event, and page D- 85, participants experiencing … event.

209. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
     September 01, 2016 - participant characteris- tics, summary results for pre-specific primary and secondary outcome measures, and adverse … • Adverse event and deaths. … ClinicalTrials.gov began to mandate reporting of adverse events in September 2009 as serious adverse … events and non-serious adverse events. … We will compare the total adverse events reported in ClinicalTrials.gov compared with the total reported

210. Kidney-Stone-Prevention Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
     June 15, 2011 - prevalence is estimated at 13 percent for men and 7 percent for women. 1,2 Following an initial stone event … adverse treatment effects may manifest in less than 1 year. … urine and blood test results, and stone characteristics; followup urine and blood test results; and event … rates for final health outcomes, intermediate outcomes, adverse events, and adherence. … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

211. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
     January 01, 2017 - metatarsophalangeal joint) and risk factors (hyperuricemia, male sex, hypertension, or >1 cardiovascular disease event … = randomized controlled trial; SOE = strength of evidence; ULT = urate-lowering therapy Table 4: Adverse … �� Gastrointestinal symptoms, fatigue, and headache �� Rare adverse effects include leukopenia, aplastic … effects include bone marrow suppression, aseptic meningitis, and dermatological adverse events �� Serious … adverse effects include gastrointestinal perforations, ulcers, and increased risk of heart attack or

212. Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mhs4-computerized-cds/rapid-research

213. Kidney-Disease-Medicine Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
     January 01, 2012 - CKD, the kidneys are damaged and/ or cannot filter blood normally.1 CKD increases the risk for many adverse … • Few trials reported adverse events. … • Although limitations in reporting impeded the quantitative synthesis of withdrawal and adverse … positive tests (for progression); medication adverse effects; increased medical visits; increased … CKD Treatment Harms Knowledge Gaps Withdrawals and adverse events were reported in few RCTs.

214. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
     May 01, 2010 - What is the comparative effectiveness of IMRT, 3DCRT, 2DRT, and proton beam therapy regarding adverse … evidence is insufficient to draw conclusions about the comparative effects of IMRT and 3DCRT for other adverse … evidence is insufficient to draw conclusions about the comparative effects of IMRT and 2DRT for other adverse … As a result, the patient may be at risk of greater adverse effects from an inadvertently high dose to … Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect

215. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - When lesinurad was combined with xanthine oxidase inhibitors, commonly reported adverse events were … However, they warned, lesinurad uptake could be limited by adverse events, such as kidney complications … Other adverse events commonly reported in the lesinurad monotherapy group included constipation, diarrhea … The experts warned that lesinurad uptake could be limited by adverse events such as kidney complications … events, which could require additional adverse event monitoring while patients are taking lesinurad

216. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - Similar to RA trials, many questions remain about the risks of these agents across a spectrum of adverse … KQ 3: For patients with PsA, do drug therapies differ in harms, tolerability, patient adherence, or adverse … events, and specific adverse events if data were available (e.g., injection-site reactions, infections … Overall adverse event profiles appeared to be similar for biologic DMARDs and placebo. … Information generally was insufficient for the comparative harms, tolerability, adverse events, and

217. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
     March 10, 2010 - The lack of information about who is most likely to experience adverse affects from the drugs. … (i.e., the difference between tam and ral on DCIS, as well as some adverse events). … The subgroup event rates are detailed in the meta-analysis figures. … perception of that event. … The adverse events seem to be described in ways that accentuate their probability.

218. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
     July 01, 2012 - MN Abstract A number of new biological markers are being studied as predictors of disease or adverse … Outcomes Time-dependent probabilities (time-to-event curves) of what is being predicted, changes or … A somewhat unique category of prognostic tests are those that can be used to predict beneficial or adverse … In a two-by-two reclassification table of only subjects who did not experience the event within the … Another formulation of the NRI calculates the probabilities of the predicted event among those that

219. Patient-Monitoring-Systems-Appendix-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-appendix-c.xlsx
     January 01, 2024 - event NR 1897 events NR NR Comparison: Arm 3 Odds Ratio: 1.88 (95% CI: 1.2 to 2.95), p=0.006 Sex, MEWS … , and activation code Lee, 2020 Arm 2 Direct calling, Daytime Mortality, 28 days after adverse event … event NR 2874 events NR NR Reference Sex, MEWS, and activation code Lee, 2020 Arm 4 EMR screening, … Daytime Mortality, 28 days after adverse event NR 3419 events NR NR Comparison: Arm 3 Odds Ratio: 1.44 … Mean: 0.54 (SD NR) NR Reference None Miles, 2023 Arm 2 Post-intervention (MEWS) Cardiac arrest code event

220. Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
     November 01, 2020 - • Both nonpharmacological and pharmacological interventions led to adverse event-related dropouts … • Adverse effects led to dropouts among a small percentage of patients for all types of pharmacological