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Showing results for "adverse event".
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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
    May 01, 2022 - NSAID Opioid increased risk of: Any adverse event: RR 1.72 (95% CI 1.29 to 2.28) Nausea: RR 2.72 … acetaminophen Opioids increased risk of: Any adverse event: RR 1.43 (95% CI 0.87 to 2.37) Nausea … Opioids were associated with increased likelihood of any adverse event (34% vs. 9%, RR 3.62, 95% CI … events versus an NSAID alone, including any adverse event (30.2% to 51.0% vs. 23.2%), nausea (7.3% … , including any adverse event, nausea, dizziness, and somnolence.
  2. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - event, versus 55.7% given placebo; serious adverse event rates were 1.6%, 2.4% and 4.1%, respectively … Similar adverse event rates were reported for secukinumab 75 mg (57.5%), 150 3 mg (62.5%), and … However, some experts were concerned about the adverse event rates reported.12,15 Some experts also … events, which could require additional adverse-event monitoring while patients are taking lesinurad … event.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
    July 01, 2023 - event rates in patients who receive implanted cardiac devices other than surgical prosthetic valves … event rates and other relevant outcomes? … In the rare event of a device infection due to an oral pathogen, it is most likely to have arisen from … a bacteremia from a common daily event such as toothbrushing or chewing food. … suggests that antibiotic prophylaxis for dental procedures is of little or no value in the rare event
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
    April 01, 2015 - Event At Least 1 Serious Adverse Event Treatment Discontinuation for Adverse Event Comparator … AE = adverse event; IFN = interferon; NR = not reported; SPMS = secondary progressive multiple sclerosis … The included studies used a wide range of reporting methods and adverse event categories that precluded … Studies reporting reasons for discontinuing medication DMT Total Number of Studies Adverse Event … Multiple sclerosis patients’ benefit-risk preferences: serious adverse event risks versus treatment
  5. effectivehealthcare.ahrq.gov/products/high-risk-drugs/rapid-research
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … pharmacologic therapy for acute pain, including any adverse event, study withdrawal due to adverse … Large increases in withdrawal due to adverse events were seen with oxcarbazepine. … Pain during the week or month following the inciting event and persistent opioid use were rarely reported
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    May 29, 2025 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and Adverse … See above Addendum Appendix Abbreviations Abbreviations for Addendum Appendix Acronym Term AE adverseevent BPI Brief Pain Inventory CT Computed Tomography EBRT external beam radiation therapy EQ-5D
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
    May 29, 2025 - among$38,589$subjects.$ From$these,$38$deaths$and$13$strokes$were$reported.$$ •$ May$reflect$low$event … &ACEI&or&ARB)& treatment$led$to$a$similar$number$of$adverse$ $ events$and$serious$adverse$events.$& … &ACEI&or&ARB)& $ Although$several$studies$collected$data$on$angioedema,$the$event$rates$were$very$low … $From$these,$38$ deaths$and$13$strokes$were$ reported.$$ •$ May$reflect$low$event$rates$ among$otherwise … &ACEI&or& ARB)& $ Although$several$studies$collected$data$ on$angioedema,$the$event$rates$were$
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
    May 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events ........ … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a. … involving CDSS to reduce medication errors and adverse drug events. … Adverse Events in Hospitals: A Quarter of Medicare Patients Experienced Harm in October 2018. … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - • BT causes more adverse events (such as worsening of asthma symptoms, respiratory infections, and … • Patients treated with BT developed the following common adverse events: bronchial irritation, chest … Serious adverse events occurred more frequently in BT-treated patients than in patients receiving sham … Serious adverse events attributed to BT were infrequent, and no deaths were reported. … The risk of adverse events is higher early in treatment, while benefit is typically observed weeks to
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
    September 14, 2016 - We will also review the FDA Adverse Event Reporting System (FAERS). … event.36 Data Synthesis We will complete a qualitative synthesis for all questions. … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will … (McGraw Hill Concise Dictionary of Modern Medicine, 2002) b) An adverse event is any undesirable experience … events (SAE): The event is serious and should be reported when the patient outcome is: death, life-threatening
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - We have added the following sentence as a Key Point: “Adverse event rates may be underestimated by … In adverse event analysis, page 45, why weren't open label run-in phase data in the withdrawal studies … In the adverse event analysis, we only included data from the RCT phases of multiphase studies in order … Some examples of imbalances in adverse event rates that favor the safety of placebo over adalimumab … We have added the following sentence as a Key Point for KQ3: “Adverse event rates may be underestimated
  13. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
    February 01, 2016 - We also evaluated adverse effects, including serious adverse events (e.g., anaphylaxis with medications … for acute LBP to be associated with increased risk of any adverse event vs. placebo (8 trials; RR, … in risk of adverse events. … Yoga: Adverse events Low Reporting of harms was suboptimal, but adverse events, when reported, were … vs. sham ultrasound in risk of any adverse event (6.0% vs. 5.9%; RR, 1.03; 95% CI, 0.49 to 2.13) or
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
    April 01, 2013 - homicide) • Perceived utility of intervention • Resilience Characteristics of trauma (KQ 3) Adverse … Critically ill patients32 Mortality Inconclusive, single trial (N=137) Insufficient Incidence of adverse … their stays in the intensive care unit or in their overall hospitalization) or in the incidence of adverse … effects before starting their study and use or adapt validated instruments to measure adverse effects … Those variables could include pretrauma factors, event characteristics, and peri-event responses.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - mellitus, what is the comparative safety of the following treatment options in terms of the following adverse … addition to updating information on the potential benefits of available treatments, conclusions regarding adverse … There have been a number of potential adverse events associated with rosiglitazone (e.g. increased
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
    September 22, 2011 - event management interventions versus usual care or placebo. … event management interventions compared with usual care. … Adverse Event Management Interventions Versus Usual Care/Placebo Key Points • There were no studies … of the effects of adverse event management interventions on health outcomes besides QOL. … Adverse Event Management Interventions Versus Usual Care/Placebo The strength of evidence on QOL was
  17. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
    March 01, 2022 - Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … pharmacologic therapy for acute pain, including any adverse event, study withdrawal due to adverse … Large increases in withdrawal due to adverse events were seen with oxcarbazepine. … Pain during the week or month following the inciting event and persistent opioid use were rarely reported
  18. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
    December 29, 2015 - event, versus 55.7% given placebo; serious adverse event rates were 1.6%, 2.4%, and 4.1%, respectively … Similar adverse event rates were reported for secukinumab 75 mg (57.5%), 150 mg (62.5%), and placebo … 4 mg, and placebo, respectively; serious adverse event rates were 4%, 10%, and 7%, respectively. … ; treatment-emergent adverse event rates were not reported. … , and placebo, respectively; serious adverse event rates after 12 weeks were 2.3%, 1.2%, and 2.7%,
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
    May 01, 2016 - systematic review evaluating the evidence regarding the effectiveness, comparative effectiveness, and adverse … Topiramate also increased binge-eating abstinence. �� Adverse effects of BED treatments were mainly … use of other sympathomimetic drugs for weight loss has been associated with serious cardiovascular adverse … Table 2: Summary of Key Findings for Adverse Effects of Pharmacological Interventions Intervention and … events, serious adverse events, and study discontinuations clearly attributable to adverse events,
  20. effectivehealthcare.ahrq.gov/products/chemotherapy-dental/research

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