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  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
    March 01, 2011 - Other adverse events. … or thiazolidinediones. 7 Outcomes of Interest Overall, few studies contained sufficient data on event … We recommend improvements in adverse event and long-term outcome reporting, with predefined outcomes … High The rates of GI adverse effects were similar for thiazolidinediones and sulfonylureas. … (continued) Gastrointestinal Moderate Metformin was associated with twice as many GI adverse event rates
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
    August 10, 2010 - children < 6 years of age with ADHD or Disruptive Behavior Disorder, what are the effectiveness and adverseevent outcomes following treatment? … Among people 6 years of age or older with ADHD, what are the effectiveness and adverse event outcomes … • Descriptive Statistics Outcomes  Numerical or statistical results of any effectiveness or adverseevent outcomes  Numerical or statistical results of any effectiveness or adverse event outcomes
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
    September 01, 2016 - is a summary of a systematic review evaluating the evidence regarding the comparative benefits and adverse … evidence suggests that there is a trend toward a higher rate of treatment discontinuation due to adverse … with SGAs. �� The evidence is also insufficient to permit conclusions about differences in serious adverse … Overview of Clinical Research Evidence (Continued) Table 4: Common Adverse Effects Reported in Studies … effects associated with MDD treatments, including the potential serious adverse effects associated
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
    January 01, 2007 - Adverse events (including 30 day mortality) No new data on adverse event rates among comparative studies … None of the studies reported data to allow a comparison of adverse event or other complication rates … Therefore, these data have been added to the adverse event section below on angioplasty cohort studies … Adverse events (including 30 day mortality) A total of 22 studies reported adverse events immediately … , though serious long-term adverse events were rare.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
    November 26, 2024 - cognitive impairment, and substance use disorders.10 This project will investigate the epidemiology and adverse … term")) OR (title: ("long term")) OR (title: ("longer term")) OR (title: (outcomes)) OR (title: ("adverseevent")) OR (title: ("adverse events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … (abstract: ("long term")) OR (abstract: ("longer term")) OR (abstract: (outcomes)) OR (abstract: ("adverseevent")) OR (abstract: ("adverse events")) OR (abstract: (consequence)) OR (abstract: (consequences
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - Response Protocol Project Title: Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse … The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … effects (e.g., bleeding).7,8 The 2019 National Action Plan for Adverse Drug Event Prevention (ADE … US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. … Advancing Medication Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
    October 01, 2006 - In the angioplasty trial, no differences were found in event rates for congestive heart failure, stroke … In the surgery trial, near-identical rates of a combined outcome of atherosclerotic cardiovascular eventAdverse events (including 30-day mortality, Table B) Adverse events were reported in 37 studies, including … No direct comparisons were made of differences in adverse event rates between 4 5 … Adverse events N/A • The evidence does not support meaningful conclusions about relative adverse events
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2_0_0.xlsx
    May 29, 2025 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
    October 01, 2023 - event*"[Title/Abstract] OR "undesired event*"[Title/Abstract] OR "medical errors"[MeSH Terms] OR "medical … event*" OR "undesired event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic mistake*" OR … event*" OR "undesired event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic mistake*" OR … event*" OR "undesired event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic mistake*" … event*" OR "undesired event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic mistake*" OR
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - Adverse events 22 Low 1 fair trial: no significant differences in ECT + rTMS specific adverse events … VNS vs. sham Adverse events 235 Low 1 fair trial: Some differences in specific adverse events reported … event Number of Strength of Comparison Outcome Subjects Evidencea Findingsb ECT vs. rTMS Withdrawals … Specific adverse events. … Adverse event reporting is quite limited and tends to cover only a short time span; what reporting does
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
    April 25, 2013 - While it is possible that adverse event rates might be somewhat different with lower baseline and target … evidence does not suggest that by following new guidelines, adverse event rates and relative effects … While it is possible that adverse event rates might be somewhat different with lower baseline and target … On- study mortality was typically determined based on adverse event data (e.g., an adverse event with … Therefore, this was not a specified endpoint and should be considered an adverse event endpoint.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. IV. … events Withdrawals because of adverse events Discontinuation rates because of adverse events … Serious adverse events Specific adverse events or withdrawals because of specific adverse events … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
    November 08, 2012 - exposed to the event. … effects of intervention(s) o Adverse effects (e.g., worsening of anxiety or agitation, increased … mania, medication dependence or misuse) o Dropout rate (overall dropout rate, dropout because of adverse … KQ 4 addresses the absolute and comparative risks of harms and adverse events from these interventions … expect these to include PTSD symptom reduction, quality of life, disability/functional impairment, and adverse
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - Brief Summary of Findings for Clinicians KEY CLINICAL ISSUE What are the relative effectiveness and adverse … This trial also sought to compare the adverse effects of epidural injections of glucocorticoids plus … There were no differences be- tween injection approaches at 6 weeks. »» There were more reported adverse … Serious adverse events (hospitalization or surgery) were rare among all patients. »» There were higher … Furthermore, the potential adverse effects of systemic glucocor- ticoids (e.g., elevated blood glucose
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - Although clozapine is often reserved for treatment-resistant patients, due to the serious adverse eventevent profiles, the evidence indicates no difference in the overall risk for adverse events between … Given the variation in specific adverse event profiles across the SGAs, withdrawals due to adverse events … SGA comparisons Overall Adverse Events • Overall adverse event rates favored SGAs when comparing haloperidol … with aripiprazole • Overall adverse event rates favored SGAs when comparing haloperidol with risperidone
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
    June 24, 2014 - Outcome(s): Health outcomes (e.g. mortality, morbidity, adverse events), functional status, patient … Does the risk of adverse effects differ according to patient baseline diet and fluid intake? c. … Does the risk of adverse effects differ according to joint vs. systemic involvement in gout? … Does the risk of adverse effects differ according to patient baseline diet and fluid intake? c. … Does the risk of adverse effects differ according to characteristics of (joint/ gout/systemic) In
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - experiencing each of the aforementioned outcomes was less than 1.5 percent; in 75 percent of studies the event … Selective outcome and analysis reporting likely – Few studies reported bleeding requiring treatment; the event … Selective outcome and analysis reporting likely – Few studies reported bleeding requiring treatment; the event … consistency – Individual studies did not provide adequate information for precise estimation of the event … Random effects meta-analysis of event outcome in the framework of the generalized linear mixed model
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
    January 01, 2022 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F1-4.xlsx
    January 01, 2022 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
    September 23, 2016 - But SGAs also have potentially serious adverse effects (e.g., cardiovascular and endocrinologic adverse … events (frequency of any adverse events reported in trials) § Withdrawals due to adverse events, … ) • Significant (major) adverse events KQ 2: • Overall adverse events (frequency of any adverse events … reported in trials) • Withdrawals due to adverse events, time to withdrawal due to adverse events … Contacting Authors: In the event that information regarding methods or results appear to be omitted

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