-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Other adverse events. … or
thiazolidinediones.
7
Outcomes of Interest
Overall, few studies contained sufficient data on event … We recommend improvements in adverse event
and long-term outcome reporting, with predefined
outcomes … High The rates of GI adverse effects were similar for thiazolidinediones and
sulfonylureas. … (continued)
Gastrointestinal Moderate Metformin was associated with twice as many GI adverse event rates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - children < 6 years of age with ADHD or Disruptive Behavior
Disorder, what are the effectiveness and adverse … event outcomes following
treatment? … Among people 6 years of age or older with ADHD, what are the
effectiveness and adverse event outcomes … • Descriptive Statistics
Outcomes Numerical or statistical
results of any
effectiveness or adverse … event outcomes
Numerical or statistical
results of any
effectiveness or adverse
event outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
September 01, 2016 - is a summary of a systematic review evaluating the evidence regarding the comparative benefits and adverse … evidence suggests that there is a trend toward
a higher rate of treatment discontinuation due to adverse … with SGAs.
�� The evidence is also insufficient to permit conclusions
about differences in serious adverse … Overview of Clinical Research Evidence (Continued)
Table 4: Common Adverse Effects Reported in Studies … effects associated with MDD
treatments, including the potential serious adverse effects
associated
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - Adverse events (including 30 day mortality)
No new data on adverse event rates among comparative studies … None of the studies reported data to allow a comparison of adverse event or other
complication rates … Therefore, these data have been added to the adverse event section below on
angioplasty cohort studies … Adverse events (including 30 day mortality)
A total of 22 studies reported adverse events immediately … , though serious long-term adverse events were rare.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
November 26, 2024 - cognitive impairment, and
substance use disorders.10 This project will investigate the epidemiology and adverse … term")) OR (title: ("long term")) OR (title: ("longer
term")) OR (title: (outcomes)) OR (title: ("adverse … event")) OR (title: ("adverse
events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … (abstract: ("long term")) OR (abstract: ("longer term")) OR (abstract:
(outcomes)) OR (abstract: ("adverse … event")) OR (abstract: ("adverse
events")) OR (abstract: (consequence)) OR (abstract: (consequences
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Response Protocol
Project Title: Making Healthcare Safer IV:
Protocols for High-Risk Drugs: Reducing Adverse … The “Protocols for High-Risk Drugs:
Reducing Adverse Drug Events Related to Anticoagulants” as a patient … effects (e.g., bleeding).7,8 The 2019 National Action Plan for Adverse Drug Event
Prevention (ADE … US
Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. … Advancing Medication
Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
October 01, 2006 - In the angioplasty
trial, no differences were found in event rates for
congestive heart failure, stroke … In the surgery trial, near-identical
rates of a combined outcome of atherosclerotic
cardiovascular event … Adverse events (including 30-day mortality, Table B)
Adverse events were reported in 37 studies, including … No direct comparisons were made of
differences in adverse event rates between
4
5 … Adverse events N/A • The evidence does not support meaningful conclusions about
relative adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2_0_0.xlsx
May 29, 2025 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
October 01, 2023 - event*"[Title/Abstract] OR "undesired event*"[Title/Abstract] OR "medical
errors"[MeSH Terms] OR "medical … event*" OR "undesired event*" OR "medical error*" OR "diagnostic error*"
OR "diagnostic mistake*" OR … event*" OR "undesired
event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic mistake*" OR … event*" OR
"undesired event*" OR "medical error*" OR "diagnostic error*" OR "diagnostic
mistake*" … event*" OR "undesired event*" OR
"medical error*" OR "diagnostic error*" OR "diagnostic mistake*" OR
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - Adverse events 22 Low 1 fair trial: no significant differences in
ECT + rTMS specific adverse events … VNS vs. sham Adverse events 235 Low 1 fair trial: Some differences in specific
adverse events reported … event
Number of Strength of
Comparison Outcome Subjects Evidencea Findingsb
ECT vs. rTMS Withdrawals … Specific adverse events. … Adverse event reporting is quite
limited and tends to cover only a short time span; what
reporting does
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - While it is possible that
adverse event rates might be somewhat different
with lower baseline and target … evidence does not
suggest that by following new guidelines, adverse
event rates and relative effects … While it is possible that adverse
event rates might be somewhat different with
lower baseline and target … On-
study mortality was typically determined based on adverse event data (e.g., an
adverse event with … Therefore, this was not a specified
endpoint and should be considered an adverse event endpoint.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - Also,
adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any
point after the treatment is received.
IV. … events
Withdrawals because of
adverse events
Discontinuation rates because
of adverse events … Serious adverse events
Specific adverse events or
withdrawals because of specific
adverse events … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
November 08, 2012 - exposed to the event. … effects of intervention(s)
o Adverse effects (e.g., worsening of anxiety or agitation, increased … mania, medication dependence or misuse)
o Dropout rate (overall dropout rate, dropout because of adverse … KQ 4 addresses the absolute and comparative risks of harms and adverse events from
these interventions … expect these to include PTSD
symptom reduction, quality of life, disability/functional impairment, and
adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - Brief Summary
of Findings for Clinicians
KEY CLINICAL ISSUE
What are the relative effectiveness and adverse … This trial also sought
to compare the adverse effects of epidural
injections of glucocorticoids plus … There were no differences be-
tween injection approaches at 6 weeks.
»» There were more reported adverse … Serious adverse events (hospitalization
or surgery) were rare among all patients.
»» There were higher … Furthermore, the potential adverse effects of systemic glucocor-
ticoids (e.g., elevated blood glucose
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - Although clozapine is often reserved for
treatment-resistant patients, due to the serious adverse
event … event
profiles, the evidence indicates no difference in the overall
risk for adverse events between … Given the variation in specific adverse event profiles
across the SGAs, withdrawals due to adverse events … SGA comparisons
Overall Adverse Events • Overall adverse event rates favored
SGAs when comparing haloperidol … with aripiprazole
• Overall adverse event rates favored SGAs when comparing
haloperidol with risperidone
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
June 24, 2014 - Outcome(s): Health outcomes (e.g. mortality, morbidity, adverse events), functional
status, patient … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c. … Does the risk of adverse effects differ according to joint vs. systemic
involvement in gout? … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c. … Does the risk of adverse effects differ according to characteristics of (joint/
gout/systemic)
In
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - experiencing each of the
aforementioned outcomes was less than 1.5 percent; in 75
percent of studies the event … Selective outcome and analysis reporting likely
– Few studies reported bleeding requiring treatment; the event … Selective outcome and analysis reporting likely
– Few studies reported bleeding requiring treatment; the event … consistency
– Individual studies did not provide adequate information for precise
estimation of the event … Random effects meta-analysis
of event outcome in the framework of the generalized linear mixed
model
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
January 01, 2022 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F1-4.xlsx
January 01, 2022 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - But SGAs also have
potentially serious adverse effects (e.g., cardiovascular and endocrinologic adverse … events (frequency of any adverse events reported in
trials)
§ Withdrawals due to adverse events, … )
• Significant (major) adverse events
KQ 2:
• Overall adverse events (frequency of any adverse events … reported in trials)
• Withdrawals due to adverse events, time to withdrawal due to adverse events … Contacting Authors: In the event that information regarding methods or results appear
to be omitted