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Showing results for "adverse event".
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1081. Liver-Cancer-Therapy Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
      May 01, 2013 - Case reports will be considered only if they report on a rare adverse event. … 0 0 0 0 Time to progression 2 0 0 0 0 2 Length of stay 0 0 1 0 0 1 Local recurrence 1 0 0 0 1 2 Adverse … TACE to TEA Insufficient One poor-quality retrospective case series (n = 60) did not report adverse … AE = adverse event; ALT = alanine aminotransferase; AST = aspartate transaminase; CI = confidence interval … Important direct health outcomes of therapy include overall survival, adverse effects, and quality

1082. Mental Health and Occupational Stress in the Emergency Medical Service and 911 Workforce: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
      January 22, 2024 - Mental Health and Occupational Stress in the Emergency Medical Service and 911 Workforce: A Systematic Review Evidence-based Practice Center Systematic Review Protocol Project Title: Mental Health and Occupational Stress in the Emergency Medical Service and 911 Workforce: A Systematic Review Publication…

1083. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
      November 01, 2017 - event (1.25% [1/84]) (SOE: insufficient) … Although six studies reported low rates (0 to 1.2%) of death or serious adverse events among patients … as requiring an exception to informed consent or the need to obtain consent prior to an overdose event … to treatment for opioid use disorder and risk of future overdose episodes, in addition to serious adverse … Adverse events after naloxone treatment of episodes of suspected acute opioid overdose.

1084. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
      May 27, 2010 - Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect … of the challenges of conducting randomized, controlled trials of IMRT to address non-xerostomia adverse … of the challenges of conducting randomized, controlled trials of IMRT to address non-xerostomia adverse … Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect … • CTCAE is a broad dictionary of adverse event terms and grades.

1085. Undescended-Testicle Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
      December 01, 2012 - These adverse events are associated with the use of the laparoscopic approach and are not unexpected … Overall, adverse effects specifically associated with surgical repair for cryptorchidism were rare.

1086. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
      December 01, 2015 - In these trials, the most common adverse events reported were headache and nasopharyngitis. … The most common adverse reactions reported, including in the long-term safety study, include appetite … The most common adverse reactions reported in patients treated with pirfenidone included nausea and … impact potential, more data demonstrating reductions in transplantation-associated complications, adverse … No statistical analyses were reported.59,60 The most common adverse reactions occurring in patients

1087. antibiotics-respiratory-infection-protocol-140922 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
      September 22, 2014 - Key Question 5: What are the comparative non-clinical adverse effects of strategies for improving the … Key Question 2 • Mortality • Antibiotic resistance • Medical complications • Adverse drug effects … Adverse!drug! effects)! KQ3:# ! Time!to!return!to!work/! school! ! Clinic/ED!visits,!admission! … Adverse!effects! of!the!strategy! … there was important differential loss to follow-up or overall high loss to follow-up; the adequacy of event

1088. Alcohol-Misuse-Drug-Therapy Clinician (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
      February 01, 2016 - a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse … Adult Dosing Mechanism of Action Common Adverse Effects Contraindications Acamprosate Oral: 666 mg ( … causing accumulation of acetaldehyde during alcohol consumption, which, in turn, produces various adverse … Clinicians are advised to refer to the prescribing information sheet for additional information on adverse … efficacy and relative effectiveness of the various medications for AUD �� Evidence related to the adverse

1089. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - The most common adverse effect was mild skin rash from the monitor patch’s electrodes; no serious adverse … Ingestible sensor (formerly known as Ingestible Event Marker or IEM): a 1 mm2 microfabricated chip … The most common adverse effect was mild skin rash from the monitor’s electrodes. … $150,000 to create its senior- specific ED and that it raised the money through an annual fundraising event … The FDA lowers the regulatory bar for ingestible event markers, downgrading them from Class II to

1090. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
      March 29, 2011 - What are the harms, including adverse events, associated with the use of sapropterin dihydrochloride … Typical cognitive development Harms and adverse events, including but not limited to the following … March 29, 2011 KQ6 KQ6 will now read: What are the harms, including adverse events, associated with … What are the harms, including adverse events, associated with the use of sapropterin dihydrochloride, … Typical cognitive development Harms and adverse events, including but not limited to the following

1091. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
      October 01, 2015 - The most common adverse reactions reported in patients treated with pirfenidone included abdominal … patients may require a dose reduction to 100 mg, twice daily, or treatment interruption to manage adverse … The most common adverse reactions reported in patients treated with nintedanib included abdominal pain … impact potential, more data demonstrating reductions in transplantation-associated complications, adverse … However, two clinical experts stated that adverse events could reduce patient acceptance.58,64 One

1092. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
      January 01, 2011 - because ESAs are very expensive, but also because higher dosing regimens of ESA are associated with adverse … What are the adverse effects or harms associated with testing using newer and/or older markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of iron status … events related to lab testing Adverse events related to management strategies KQ1 KQ … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

1093. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
      January 01, 2016 - No serious adverse events were reported. … event reported in the 3-year, phase III trial for the fluocinolone acetonide implant was cataract … adverse event profile limits the implant’s potential to improve health outcomes for patients with … Conversely, the adverse-event profile could be a barrier to adoption, noted several experts, at least … Over 2 years, the most frequent ocular serious AE [adverse event] (SAE) and AE were cataract (2.1%

1094. Cad-Women-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-treatment_executive.pdf
      August 01, 2012 - What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … • Adverse effects of interventions: adverse drug reactions, radiation exposure, access site complications … Data Synthesis and Analysis We synthesized the primary literature by continuous data (e.g., age, event

1095. Meditation Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
      October 17, 2012 - Adverse events (AE) may occur at any point after the meditation program. … We will model rare adverse events (<1%) using the Peto Odds ratio approach which has the best confidence … model is statistically underpowered.33 If we detect an imbalance in trial sizes and number of zero event … model is statistically underpowered.33 If we detect an imbalance in trial sizes and number of zero event … Adverse events (AE) may occur at any point after the meditation program.

1096. Topic 0556 CE of Treatments for Diabetic Peripheral Neuropathy NSD SJ clean (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0658-140831.pdf
      July 19, 2014 - disability, foot infection or ulceration, amputation, progression of neuropathy, pain, occurrence of adverse

1097. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
      August 22, 2008 - KQ 4: In patients with CF, what is the frequency of nonmalignant serious adverse effects resulting from … KQ 6: In patients with CF, how is efficacy, effectiveness, safety or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety or adverse events of treatment … Important health outcomes in KQ2 and adverse events in KQ4 associated with rhGH will be meta-analyzed … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will

1098. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
      October 01, 2010 - For time to event data, the measure is hazard ratio (HR), and most commonly estimated from the Cox … All these models could be used to combine measures for continuous, count and time to event data, as … Rate ratio should be used for count data and hazard ratios for time-to-event data. … needed-to-treat-related concepts for assessing treatment efficacy in the presence of treatment-induced adverse … Practical methods for incorporating summary time-to-event data into meta- analysis.

1099. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
      October 01, 2010 - For time to event data, the measure is hazard ratio (HR), and most commonly estimated from the Cox … All these models could be used to combine measures for continuous, count and time to event data, as … Rate ratio should be used for count data and hazard ratios for time-to-event data. … needed-to-treat-related concepts for assessing treatment efficacy in the presence of treatment-induced adverse … Practical methods for incorporating summary time-to-event data into meta- analysis.

1100. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
      November 09, 2011 - Also, the potential for unexpected effects, which may be adverse, needs to be considered. … The analytic framework to illustrate the population, interventions, outcomes and adverse effects will … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will