-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - • In THR, LMWH has lower VTE and
adverse event risks than unfractionated
heparin; LMWH and aspirin … One NRCS had high risk of bias for adverse event
reporting and one was unclear. … Only about half of studies
reported major bleeding, the adverse event of greatest
concern for most … For VTE prophylaxis studies, there is a
fairly standard list of VTE and adverse event outcomes that … Larger RCTs should evaluate differences in treatment
and adverse event effects in relevant subgroups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
March 01, 2022 - event; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … event and serious
adverse events with
adalimumab + MTX compared
to abatacept + MTX.21
Tocilzumab
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … event and serious
adverse events with
adalimumab + MTX compared
to abatacept + MTX.21
Tocilzumab
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Studies that reported fracture only as an adverse
event were excluded from effectiveness analysis; … were included in the adverse event analysis … included
information on the relationship between the adverse event
and the drug. … event analyses. … event.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
December 20, 2011 - , rather
than the event itself, determines an individual’s mood. … events: overall adverse events, withdrawals due to adverse events,
and specific adverse events (including … KQ 6 looks as the adverse effects
of these interventions. … effects), we will evaluate
the trials included in KQs 1 through 4 that report adverse
effects. … • Requires patient to associate each symptom with a specific traumatic event.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease-appendix-a.pdf
August 31, 2023 - arteriovenous or artery or arteries or arterial or vein or vein or veins or cerebrovascular) adj3
("adverse … event*" or anomaly or anomalies or abnormalit* or defect or defects or disease*
or complication* or … disturbance* or infection* or inflammation* or lesion* or
malformation* or symptom* or syndrome* or event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
October 01, 2015 - events (SOE: low
for local adverse events; insufficient for systemic
adverse events). … BCG Versus MMC:
• BCG was associated with increased risk of any local
adverse event (2 trials; RR, … • BCG was associated with increased risk of any
systemic adverse event (2 trials; RR, 2.01; 95% CI … risk of any
local adverse event (2 trials; RR, 2.01; 95% CI,
1.59 to 2.54; I2 = 0%), granulomatous … MMC:
Systemic adverse
events
Low BCG was associated with increased risk of any
systemic adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Evidence-Tables-E1-E4_0.xlsx
May 29, 2025 - Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention A, N of Serious … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - that have potential analgesic effects as well as the
potential for addiction, misuse, and serious adverse … There may be no increase in
risk of serious adverse events (SOE: low) or withdrawal due to adverse events … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive
deficits) and outcomes … Other prioritized adverse events
(cannabis use disorder [CUD], psychosis, cognitive deficits) and the … event; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol.pdf
September 13, 2024 - cognitive impairment, and
substance use disorders.10 This project will investigate the epidemiology and adverse … Outcome
o Short-term
Overdoses, fatal and non-fatal
Health measures (cardiovascular, injuries, adverse … term")) OR (title: ("long term")) OR (title: ("longer
term")) OR (title: (outcomes)) OR (title: ("adverse … event")) OR (title: ("adverse
events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … event")) OR (abstract: ("adverse
events")) OR (abstract: (consequence)) OR (abstract: (consequences
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
January 01, 2020 - TEP # 1 Introduction—
Page 3 lines 11-
13
Change to “..the Vaccine Adverse Event Reporting System … It
is also possible to have high or moderate
strength of evidence for an extremely rare
adverse event … Event Monitoring Substudy which comprised a
subset of 6600+ subjects. … Similarly, event severity
was poorly described. … An
understanding of the severity of an adverse event is
necessary for decision-makers to determine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - • Safety (focusing on serious adverse event rates, overall adverse event rates, and withdrawals … Key Points
• Cough was modestly more frequently observed as an adverse event in groups treated with … However, the nature of serious adverse event reporting was
inconsistent, and rates of serious adverse … Depending on the definition used, adverse event rates ranged from 0 to 100
percent (median 32 percent … The one adverse event for which significant differential effects were apparent is cough.
-
effectivehealthcare.ahrq.gov/products/COVID-19-pharmaceutical-treatments/rapid-research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - event; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Differences in Harms (Adverse Events)
(KQ 4a)
We analyzed adverse-events data from 92 head-to-head
efficacy … On
average, 63 percent of patients in efficacy trials
experienced at least one adverse event. … Other Severe Adverse Events
The existing evidence on the comparative risk for rare
but severe adverse … Comparative Harms and Adherence of
Immediate- Versus Extended-Release
Formulations (KQ 4b)
Overall, adverse-event … Likewise, adverse-event rates were similar between
paroxetine IR and paroxetine CR, as well as venlafaxine
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
January 01, 2025 - that have potential
analgesic effects as well as the potential for addiction, misuse, and serious adverse … There may be no increase in
risk of serious adverse events (SOE: low) or withdrawal due to adverse events … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive
deficits) and outcomes … Other prioritized adverse
events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … event; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - Many questions remain
about the risks of these agents across a spectrum of
adverse events from relatively … In general, adverse events did not differ significantly
between biologic and synthetic DMARDs. … Studies were
too small to assess reliably differences in rare but
severe adverse events. … Studies, however, were too small to assess
reliably differences in rare but severe adverse events. … The
groups did not differ in serious adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - Events of
Interest
Adverse Events Depression treatment-related adverse events. … The adverse events measure also required a modification to capture adverse events related to
procedures … Additional
procedure codes were added to the Adverse Event value sets. … Potential challenges related to the
availability of PHQ-9, adverse event, suicide, and mortality data … Adverse Events Data
The intent of the adverse events measure is to capture all adverse events related
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Gastrointestinal adverse events/problems. … Only one study reported an adverse event of
thrombocytopenia and leucopenia, making comparisons
between … , and consistently report all adverse
events (not using aggregated events). … medications in withdrawals due to unspecified adverse events.
events
4&5k. … event findings reported
above.
6.