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61. Finding Evidence for Comparing Medical Interventions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
    January 01, 2011 - For example a term such as “adverse drug reaction” would not be appropriate for nondrug interventions … Incomplete evidence: the inadequacy of databases in tracing published adverse drug reactions in clinical … TOXICITY/ Drug terms AND (exp ADVERSE DRUG REACTION/ OR Exp Side- Effect/ ) A-2 Loke … effects /poisoning /toxicity /chemically induced /contraindications /complications /side effect /adverse … drug reaction /drug toxicity /complication Scottish Intercollegiate Guidelines Network (SIGN)

62. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - Treatments for Schizophrenia in Adults: A Systematic Comparative Effectiveness Review Number 198 Treatments for Schizophrenia in Adults: A Systematic Review Evidence Summary Condition and Treatment Strategies Schizophrenia is a chronic mental health condition that most often presents in early adulthood and ca…

63. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - Layout 1 Background Osteoarthritis is a chronic condition involving degeneration of cartilage within the joints. It is the most common form of arthritis and is associated with pain, substantial disability, and reduced quality of life.1 Surveys indicate that 5 to 17 percent of United States (U.S.) adults have symptom…

64. Major-Depressive-Disorder Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
    December 01, 2015 - 1 Comparative Effectiveness Review Number 161 Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive Disorder Executive Summary Background Major depressive disorder (MDD)1 is the most prevalent and disabling form of depression, affecting more than 16 percent of U.S…

65. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
    March 01, 2022 - AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care AHRQ EVIDENCE-BASED PRACTICE CENTER PROGRAM RESEARCH GAPS SUMMARY: PRIMARY CARE An EPC publication summarizing evidence gaps identified across recent EPC reviews for select healthcare topics Prepared by: Angela Carr, R.N., M.…

66. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - Layout 1 Background Depressive disorders such as major depressive disorder (MDD), dysthymia, and subsyndromal depression (including minor depression) may be serious disabling illnesses. MDD is the most prevalent, affecting more than 16 percent (lifetime) of U.S. adults. In 2000, the U.S. economic burden of depressiv…

67. Osteoporosis-Bone-Fracture Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
    March 01, 2012 - 1 Comparative Effectiveness Review Number 53 Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report Executive Summary Background Osteoporosis is a systemic skeletal disease characterized by decreasing bone mass and microarchitectural deterioration of bo…

68. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
    January 31, 2013 - What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … drug reactions, bleeding, contrast nephropathy, radiation, infection, exercise-related harms, … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions

69. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy Source: www.effectivehealthcare.ahrq.gov Published Online: July 01, 2010 Evidence-Based Practice Center Systematic Review Protocol Project Title: Evaluation of Effectiveness and Safety of Antiepileptic Medicati…

70. Prioritization and Selection of Harms for Inclusion in Systematic Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - Prioritization and Selection of Harms for Inclusion in Systematic Reviews Prioritization and Selection of Harms for Inclusion in Systematic Reviews Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Presenter Presentation Notes P…

71. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Layout 1 Background Type 2 diabetes is characterized by insulin resistance accompanied by progressive deficiency in insulin secretion. Type 2 diabetes is an increasingly common disease that is closely associated with obesity. In 2005, the prevalence of Americans with diagnosed type 2 diabetes was 2.4 percent for ad…

72. Survey of Medicare Part D Plans’ Medication Therapy Management Programs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research-2007.pdf
    January 01, 2007 - drug events, improving patient clinical outcomes, or raising quality of life.10-14 Information about … drug events.4, 57, 58 Despite this, these programs formed the backbone of most of the MTM programs, … Fatal adverse drug events: the paradox of drug treatment. J Intern Med 2001;250(4):327-41. 19. … Adverse drug events in emergency department patients. … Role of pharmacist counseling in preventing adverse drug events after hospitalization.

73. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Arthritis and Nontraumatic Joint Disease AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 01: Arthritis and Nontraumatic Joint Disease Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither…

74. App-E-Surv-Rept-1-Acute-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
    May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…

75. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
    May 19, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: May 19, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics – Update I. Background and Objectives for the Sys…

76. Acute Treatment for Episodic Migraine: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
    June 01, 2022 - Acute Treatment for Episodic Migraine: Surveillance Report 2 Acute Treatments for Episodic Migraine: Surveillance Report 2 Literature Update Period: September 2, 2021, Through December 30, 2021 Background and Purpose This report is the second surveillance report for the Agency for Healthcare Research and Quali…

77. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
    December 15, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: April 28, 2011 Page 1 of 26 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular D…

78. White Paper: Standardized Library of Lumbar Spondylolisthesis Outcome Measures (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
    March 01, 2021 - White Paper: Standardized Library of Lumbar Spondylolisthesis Outcome Measures Research White Paper Standardized Library of Lumbar Spondylolisthesis Outcome Measures Research White Paper Standardized Library of Lumbar Spondylolisthesis Outcome Measures Prepared for: …

79. White Paper: Standardized Library of Lumbar Spondylolisthesis Outcome Measures (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
    March 01, 2021 - White Paper: Standardized Library of Lumbar Spondylolisthesis Outcome Measures Research White Paper Standardized Library of Lumbar Spondylolisthesis Outcome Measures Research White Paper Standardized Library of Lumbar Spondylolisthesis Outcome Measures Prepared for: …

80. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: August 05, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness and Safety of Analgesics for Osteoarthritis – An Update to the 2006 Report I. Background and Objectives f…