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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-depression-suicide-risk-children-adolescents
August 13, 2020 - Labeling or stigma
Inappropriate/unnecessary treatment
KQ 5 (pharmacotherapy only):
Serious adverse … effects
Withdrawals due to adverse effects
Suicidality
All other outcomes
Outcome assessment
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RrE4_peSk5zVH3cCf77at3
June 24, 2025 - partner violence (IPV) and caregiver abuse of older and
vulnerable adults can cause acute and long-term adverse … of
abuse/neglect and associated
physical and mental morbidity (eg,
rates of emergency room visits);
adverse … to IPV, such as education
about child development, counseling about other factors associ-
ated with adverse … assessed a clinic-based behavioral
counseling intervention for women with 1 or more risk factors for
adverse … Overall, evidence on the adverse effects of
interventions was limited.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary24/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
March 11, 2014 - Even infrequent use increases the risk for serious adverse events by increasing risk-taking behaviors … Harms of Interventions
We identified no studies that reported adverse events related to interventions … One trial also showed a statistically significant effect for inhalant use
3 (adverse events) … NA
0
0
NA
NA
NA
NA
No studies assessed adverse events of the intervention
NA = … What are the adverse events of primary care behavioral counseling drug use interventions?
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening-october-2018
October 23, 2018 - abuse include death, 9 higher risk of nursing home placement 10 among those referred to APS, and adverse … Limited evidence showed no adverse effects of screening or interventions for IPV. … violence, physical violence, or stalking, more than 10% experience at least 1 form of an IPV-related adverse … of Screening and Treatment
Two fair-quality RCTs reported on harms of screening and identified no adverse … Intimate partner violence increases adverse outcomes at birth and in early infancy.
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www.uspreventiveservicestaskforce.org/uspstf/document/article/prostate-cancer-screening-2008
August 05, 2008 - Long-term adverse effects of false-positive PSA screening test results are unknown. … percentage of free PSA. 6-9
Potential harms from PSA screening include additional medical visits, adverse … never have caused symptoms in the patient’s lifetime, leading to unnecessary treatment and associated adverse … effects ; mass screening/adverse effects ; mass screening/psychology ; anxiety ; quality of life … Although we found some evidence that false-positive PSA test results are associated with adverse psychological
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-women-and-elderly-adults/intimate-partner-violence-and-elderly-abuse-screening-2004
March 08, 2004 - adverse effects of screening or interventions. … The Adverse Childhood Experiences (ACE) Study. Am J Prev Med 1998;14(4):245-58.
22. … Adverse childhood experiences and risk of paternity in teen pregnancy. … Arrow 3: What are the adverse effects of screening? … Arrow 5: What are the adverse effects of intervention?
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/cognitive-impairment-in-older-adults-screening
February 25, 2020 - Studies were required to report total adverse events, withdrawals attributable to adverse events, or … serious adverse events that resulted in unexpected medical care, morbidity, or mortality. … Acetylcholinesterase Inhibitors and Memantine
Overall, adverse effects from medications were quite … Total adverse events were also statistically significantly higher for all 3 types of AChEI vs placebo … Overall, there did not appear to be differences in total serious adverse events for these medications
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www.uspreventiveservicestaskforce.org/uspstf/document/published-response---will-recommendations-against-spirometry-make-chronic-obstructive-pulmonary-disease-harder-to-treat/chronic-obstructive-pulmonary-disease-copd-screening-2008
November 15, 2008 - The USPSTF judged that the harms of such screening—false-positive test results leading to adverse effects
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/perinatal-depression-interventions-to-prevent
February 23, 2023 - intensive care unit admission
Serious harms reported in trials of treatment benefit
Withdrawals due to adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
March 14, 2014 - Potential Adverse Effects of Screening
Studies of adverse effects of screening are limited but have … not found adverse psychological effects (i.e., labeling) in patients identified with abnormal lipids
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aJ-xmGLsKqLQbQsBqodKZ5
January 01, 2001 - Potential Adverse Effects of Screening
Studies of adverse effects of screening are limited but
have … not found adverse psychological effects (i.e., label-
ing) in patients identified with abnormal lipids
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - breastfeeding and recommends that the potential benefits should be considered along with any potential adverse … with patients, patient education, reminder systems for taking medication, and attention to medication adverse … PrEP with TDF/FTC or tenofovir disoproxil fumarate alone was associated with increased risk of kidney adverse … 32
One trial (n = 5387) reported no differences between TAF/FTC and TDF/FTC in rates of any kidney adverse … that PrEP is associated with a small magnitude of harms, which include kidney and gastrointestinal adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/gestational-diabetes-mellitus-screening-january-2014
January 14, 2014 - history (that is, in a first-degree relative) of diabetes, and no history of glucose intolerance or adverse … Possible adverse effects of treatment include neonatal or maternal hypoglycemia and maternal stress. … screening practices (overall RR, 0.55 [95% CI, 0.10 to 2.97]; n = 2054). 1 , 13
The Hyperglycemia and Adverse … Screening for and detecting GDM provides a potential opportunity to prevent adverse outcomes. … Hyperglycemia and adverse pregnancy outcomes. N Engl J Med . 2008;358:1991-2002. 15.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - Although statins in middle-aged and older adults appear to be relatively safe and short-term adverse … events generally resolve with discontinuation of therapy, long-term adverse effects of statins started … Long-term intraindividual cholesterol variability: natural course and adverse impact on morbidity and … psychosocial consequences such as anxiety, overdiagnosis, and others as identified in the literature)
KQ 2: Adverse … function tests or creatine phosphokinase levels, and others as identified in the literature)
KQ 6: Other adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Wx_w92ukxeDvNShoRQXbhP
September 06, 2016 - A few studies also reported on gastrointestinal adverse
events. … treated with isonia-
zid had a higher risk of medication discontinuation because of
gastrointestinal adverse … , 0.76-3.40]) in 2 studies.2 All 5 studies also reported on
discontinuation of treatment because of adverse … would occur (depending on type of
treatment), and 111 persons would discontinue treatment because
of adverse … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8JYDupJfG6LdRn7A6FkqXX
March 01, 2016 - antioxidant vitamins
and mineral supplements is not associated with increased risk of
most serious adverse … with
greater likelihood of withdrawal vs sham therapy; there were no
differences in serious or other adverse … .1,4 Two
trials on the treatment of early AMD reported no association be-
tween supplement use and any adverse … event, serious adverse
events, serious ocular events, or withdrawal due to adverse events.1
Treatment
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan18/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
May 15, 2013 - What are the adverse effects of primary care–relevant behavioral counseling drug use interventions? … biochemical verification)
No use
Frequency of use
Quantity of use
KQ 3: (adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/dCH2CMqVyAzf4eyj-ch6H3
August 09, 2016 - Bile acid–sequestering agents were commonly
associated with adverse gastrointestinal symptoms and poor … No severe, permanent harms of statins were
reported, and reported treatment adverse events usually did … resolved with treatment discontinuation.33 Ezetimibe mono-
therapy was not associated with serious adverse … Fair
Key question 4:
Adverse effects of
screening
0 0 No evidence on harms of
screening. … Treatment studies should systematically re-
port adverse effects of treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/EGPJ5VSbLv4_cDB7fQBmGR
May 01, 2014 - Risk factors for suicide attempt include presence of a mental
health disorder; serious adverse childhood … Other important risk factors for suicide attempt in-
clude serious adverse childhood events; family history … Potential Harms of Screening
Three studies reported on the potential adverse effects
of screening. … Few treatment trials in adults reported adverse events. … participants in the treat-
ment group than in the placebo group withdrew from the
study because of adverse
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/h-w99jVsodSL33kV2h2_qW
April 17, 2018 - Eight studies (n = 4107) evaluat-
ing exercise interventions reported on harms; in general, adverse … events were minor.8,10 The most common adverse events included
pain or bruising related to exercise. … or severe adverse events, although ascertain-
ment of adverse events was unclear.8 One study on a single … psy-
chological intervention reported no adverse events.25 The remain-
ing studies did not report on … harms or adverse events.