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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/UXw277rnvJ8e_Dfsh4V3K3
    July 26, 2022 - The data on health outcomes (KQ1) and adverse events (KQ4) did not allow for quantitative pooling because … Twenty-three of the 113 included trials specifically mentioned the occurrence of adverse events or lack … of adverse events (n = 12 452). … Thirteen trials reported adverse events or serious adverse events of any kind,29-31,33,41,48,51,56,62,82,114,132,136 … although 7 of these trials only stated that no adverse events were reported or that no adverse events
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
    May 20, 2014 - Risk factors for suicide attempt include presence of a mental health disorder; serious adverse childhood … Other important risk factors for suicide attempt include serious adverse childhood events; family history … Potential Harms of Screening Three studies reported on the potential adverse effects of screening … Few treatment trials in adults reported adverse events. … of participants in the treatment group than in the placebo group withdrew from the study because of adverse
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-screening-november-2016
    August 06, 2015 - KQ 4: Reduced rates (or frequency) of subclinical HSV-2 viral shedding KQ 6: Treatment-related adverse … events (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related to
  4. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan34/sexually-transmitted-infections-behavioral-counseling-september-2014
    May 15, 2013 - What adverse effects are associated with primary care behavioral counseling interventions to prevent … target populations (e.g., decrease in substance abuse/misuse among current drug users) KQ 4: Adverse
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan17/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
    May 15, 2013 - What are the adverse effects of primary care–relevant behavioral counseling interventions for healthy … outcomes (physical activity, dietary intake or patterns), self-reported or objectively measured KQ 4: Adverse
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3Kwu7j_WfCFQSnSzqrDWwt
    June 20, 2019 - benefit from risk-reducing medications for breast cancer, as well as evidence on the effectiveness, adverse … , or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse … , or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse … Vasomotor symptoms (hot flashes) are a common adverse effect of both medications. … Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation.
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkowkNFvCYh9hMnEBcCkGh
    May 01, 2004 - amblyopia Refractive error associated with amblyopia Asymptomatic children younger than age 5 years Adverse … KQ 1 Screening Strabismus KQ 3 Normal visual acuity Association KQ 9 (Added to 2003 update) Adverse … What are the adverse effects of screening? 8. What are the adverse effects of treatment? … in the adherence to sound eye was decreased from treatment, and baseline by 1 line in 14 patients adverse
  8. www.uspreventiveservicestaskforce.org/uspstf/recommendation/impaired-visual-acuity-in-older-adults-screening-2016
    March 01, 2016 - antioxidant vitamins and mineral supplements is not associated with increased risk of most serious adverse … with greater likelihood of withdrawal vs sham therapy; there were no differences in serious or other adverse … 4 Two trials on the treatment of early AMD reported no association between supplement use and any adverse … event, serious adverse events, serious ocular events, or withdrawal due to adverse events. 1 Treatment
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/9K4QQKvhXZNJLCxNX3FkZm
    May 01, 2008 - It is hoped that the Hyperglycemia and Adverse Pregnancy Outcome study, which is now in the data analysis … but the USPSTF was unable to find sufficient evidence that gestational dia- betes screening reduced adverse … The primary adverse effects associated Clinical GuidelinesScreening for Gestational Diabetes Mellitus … The relationship between gestational diabetes and adverse outcomes is further confounded by the fact … diabetes, 3) body mass index of 25 kg/m2 or less, 4) no previous history of abnormal glucose tolerance or adverse
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KdQef_VDT2kmHDX4ddNWmR
    August 01, 2022 - events reported with isoniazid (RR, 1.50 [95% CI, 1.18-1.89]) and a greater risk of gastrointestinal adverse … Recent trials also reported on discontinuation due to adverse events. … receiv- ing rifapentine plus isoniazid vs isoniazid alone reported increased dis- continuation due to adverse … this was statistically significant in only 1 trial.9,28 Overall, study re- ports of gastrointestinal adverseAdverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/hepatitis-c-virus-infection-screening-2004
    March 08, 2004 - Although risks of biopsy and treatment appear minimal or self-limited, data on other adverse effects … The most common adverse event is an influenza-like syndrome involving myalgias, fevers, and fatigue. … Because of the long duration (6 months) of interferon regimens, adverse effects of treatment can have … Good Common adverse events with interferon-based therapy are self-limited influenza-like symptoms, … We also reviewed adverse outcomes from screening and treatment including side effects from treatment,
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening-2008
    July 15, 2008 - Treatment Potential harms associated with treatment of asymptomatic bacteriuria include: Adverse … and Early Treatment: Potential harms associated with treatment for asymptomatic bacteriuria include adverse
  13. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … alternative therapy to positive airway pressure for patients with OSA who prefer them or for those with adverse … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-anxiety-children-adolescents
    March 29, 2022 - Labeling or stigma Inappropriate/unnecessary treatment KQ 5 (pharmacotherapy only): Serious adverse … effects Withdrawals due to adverse effects Suicidality All other outcomes Outcome assessment
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-depression-suicide-risk-children-adolescents
    August 13, 2020 - Labeling or stigma Inappropriate/unnecessary treatment KQ 5 (pharmacotherapy only): Serious adverse … effects Withdrawals due to adverse effects Suicidality All other outcomes Outcome assessment
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RrE4_peSk5zVH3cCf77at3
    June 24, 2025 - partner violence (IPV) and caregiver abuse of older and vulnerable adults can cause acute and long-term adverse … of abuse/neglect and associated physical and mental morbidity (eg, rates of emergency room visits); adverse … to IPV, such as education about child development, counseling about other factors associ- ated with adverse … assessed a clinic-based behavioral counseling intervention for women with 1 or more risk factors for adverse … Overall, evidence on the adverse effects of interventions was limited.
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening-1996
    January 01, 1996 - Adverse effects of screening tests are an important consideration. … Adverse effects, such as unnecessary physician visits, heightened anxiety levels, or increased radiographic … mortality achieved by screening women aged 40-49 is of sufficient magnitude to justify the potential adverse … anxiety and diagnostic evaluation, although a small randomized clinical trial 29 did not find such adverse … Given the present state of knowledge and the potential adverse effects and opportunity cost, a recommendation
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review79/ovarian-cancer-screening-2004
    May 15, 2004 - An arrow along this route also branches from "interventions" to "adverse effects" and stops. … It goes directly from "screening" to "adverse effects" and stops. … (This "adverse effects" is placed separately from the "adverse effects" that springs from "interventions
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/cognitive-impairment-in-older-adults-screening
    February 25, 2020 - Studies were required to report total adverse events, withdrawals attributable to adverse events, or … serious adverse events that resulted in unexpected medical care, morbidity, or mortality. … Acetylcholinesterase Inhibitors and Memantine Overall, adverse effects from medications were quite … Total adverse events were also statistically significantly higher for all 3 types of AChEI vs placebo … Overall, there did not appear to be differences in total serious adverse events for these medications
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/DCfAJZvNDzSYu7NqLJX2bv
    March 01, 2016 - found use of antioxidant vitamins and mineral supplements not associated with increased risk of most adverse … events (93% vs 89%; RR, 1.05; 95% CI, 0.97-1.13), serious adverse events (31% vs 30%; RR, 1.04; 95% … CI, 0.72-1.49), or serious ocular adverse events (8.2% vs 7.0%; RR, 1.18; 95% CI, 0.50-2.75)40; one other … pub- lished subsequent to the 2009 USPSTF review found no difference in risk of withdrawals due to adverse … Fair Abbreviations: AE, adverse event; AREDS, Age-Related Eye Disease Study; AMD, age-related macular

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