-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - events (frequency of any adverse events reported in trials)
• Withdrawals due to adverse events, time … • Significant (major) adverse events
Key Question 2:
• Overall adverse events (frequency of any adverse … events reported int rials)
• Withdrawals due to adverse events, time to withdrawal due to adverse events … Given the variation in specific adverse event profiles
across the SGAs, withdrawals due to adverse events … and ziprasidone
Withdrawal Due to
Adverse Events
• Withdrawals due to adverse
events were significantly
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - Adverse events 22 Low 1 fair trial: no significant differences in
ECT + rTMS specific adverse events … VNS vs. sham Adverse events 235 Low 1 fair trial: Some differences in specific
adverse events reported … Safety, Adverse Events, and Adherence
(KQ 4)
Direct evidence. … Specific adverse events. … More careful and consistent assessment of adverse
events is required.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
June 01, 2016 - Propranolol was associated with short-term (<6 months)
adverse effects such as hypotension, hypoglycemia … Minor adverse effects such as cold extremities, diarrhea, rash, and sleep
changes were also reported … .
���
Timolol (topical) Adverse effects 4 353 No adverse effects were observed. ���
STEROIDS
All … steroids Adverse effects 16 3291 Steroids were associated with clinically important adverse effects, … effects associated
with the different interventions for IH
��Potential long-term adverse effects
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Key Question 3: Adverse Events and Side Effects
This Key Question was addressed by 107 studies. … Other adverse events. … Some adverse effects, such as
congestive heart failure, may take years to develop, and
others, such as … We recommend improvements in adverse event
and long-term outcome reporting, with predefined
outcomes … High The rates of GI adverse effects were similar for thiazolidinediones and
sulfonylureas.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
August 01, 2023 - Some of these patients suffer an
adverse event because of the incorrect diagnosis (~2.0%), and some … of these
adverse events are serious (~0.3%). … This translates to about 1 in 18 ED patients
receiving an incorrect diagnosis, 1 in 50 suffering an adverse … the United States that 7.4 million (5.7%) patients are misdiagnosed, 2.6 million
(2.0%) suffer an adverse … average diagnostic performance, each year this would be over 1,400
diagnostic errors, 500 diagnostic adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - = randomized controlled trial; SOE = strength of evidence;
ULT = urate-lowering therapy
Table 4: Adverse … �� Gastrointestinal symptoms, fatigue, and headache
�� Rare adverse effects include leukopenia, aplastic … effects include bone marrow suppression, aseptic meningitis, and dermatological adverse events
�� Serious … adverse effects include gastrointestinal perforations, ulcers, and increased risk of heart attack or … with the various treatment
strategies
��The role of ULT in patients with gout and the potential
adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - events:
1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70
Any adverse … events [(n/N (%)]
1 serious adverse events:
6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events: … Fesoterodine resulted in
higher rates of adverse effects and
discontinuation of treatment due to
adverse … events [(n/N (%)]
1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events … Fesoterodine resulted in higher rates of
adverse effects and discontinuation of treatment due to
adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - But SGAs also have
potentially serious adverse effects (e.g., cardiovascular and endocrinologic adverse … Harms Outcomes:
KQ 1:
§ Overall adverse events (frequency of any adverse events reported in
trials … events (frequency of any adverse events reported in
trials)
§ Withdrawals due to adverse events, … )
• Significant (major) adverse events
KQ 2:
• Overall adverse events (frequency of any adverse events … reported in trials)
• Withdrawals due to adverse events, time to withdrawal due to adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
December 01, 2015 - Evidence on adverse effects was
insufficient. … Adverse effects did not differ
between groups. … Data were insufficient for adverse effects. … Withdrawals
due to adverse effects, but not any specific adverse effect
or overall withdrawals, were … long-term use or rare adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
July 01, 2023 - Rapid Response: Efficacy of Dental Services for Reducing Adverse Events in Those Undergoing Insertion … Cardiovascular Devices
Rapid Response
July 2023
Efficacy of Dental Services for Reducing
Adverse … Pre-Cardiac
Dental Treatment Does Not Increase the Risk of
Adverse Events. … Efficacy of Dental Services for
Reducing Adverse Events in Those Undergoing Insertion of Implantable … This is especially
important in those patients at risk
of the highest adverse outcome
from VGS IE.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
May 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug
Events ........ … Reducing Adverse Drug Events Related to Anticoagulant
Use in Adults
9a. … involving
CDSS to reduce medication errors and adverse drug
events. … Adverse Events in Hospitals: A
Quarter of Medicare Patients Experienced
Harm in October 2018. … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults
9a.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
March 08, 2012 - Adverse local effects may include
nosebleeds, stinging, burning, and dryness. … Other local adverse effects may include nosebleeds, stinging, burning,
and dryness. … Local adverse effects may include
nosebleeds and nasal and oral dryness. … How do adverse effects vary with intermittent or continuous use? … Table 4 lists systemic and local adverse effects of interest.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - To assess adverse
effects and treatment discontinuation due to adverse
effects, we analyzed all included … Adverse Effects With Drugs for Chronic Migraine
Onabotulinumtoxin A resulted in adverse effects and … Increase in risk of adverse
effects was dose responsive. … Adverse Effects With Drugs for Episodic Migraine
Bothersome adverse effects leading to treatment
discontinuation … in trials with higher
placebo rates of adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - informative
- There is new evidence available for KQ1 (effectiveness,
health outcomes) and KQ3 (adverse … , bone density, and cosmetic adverse effects? … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … , bone density, and cosmetic adverse effects? … , bone density, and cosmetic adverse effects?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - informative
- There is new evidence available for KQ1 (effectiveness,
health outcomes) and KQ3 (adverse … , bone density, and cosmetic adverse effects? … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … , bone density, and cosmetic adverse effects? … , bone density, and cosmetic adverse effects?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
January 01, 2022 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … B
Total patients reporting treatment related adverse event: 21.1% (71/337) vs. 35.0% (118/337), RR 0.60 … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - spe-
cific types of chronic pain, considering the effects on
pain, function, quality of life, and adverse … • Small to moderate, dose-dependent increases in
withdrawal due to adverse events were found with … overdose, misuse, dependence, withdrawals
due to adverse events, and serious adverse
events, and … specific adverse events? … Harms
Across all classes, incidence of serious adverse
event (SAEs) was low.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - Harms and Adverse Events
a. … adverse events, with no difference in risk of serious adverse events
(SOE: low) … morphine; effects on pain, SF-36 physical and mental health; adverse events were
inconsistent, with … Rates
of adverse events of long-acting opioids in a state
medicaid program. … Opioid medication discontinuation
and risk of adverse opioid-related health care events.