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Showing results for "adverse".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
    May 29, 2025 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … B % (n/N) Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18) Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
    May 29, 2025 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … B % (n/N) Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18) Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse
  3. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - Many questions remain about the risks of these agents across a spectrum of adverse events from relatively … In general, adverse events did not differ significantly between biologic and synthetic DMARDs. … Studies were too small to assess reliably differences in rare but severe adverse events. … Studies, however, were too small to assess reliably differences in rare but severe adverse events. … The groups did not differ in serious adverse events.
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - Differences in Harms (Adverse Events) (KQ 4a) We analyzed adverse-events data from 92 head-to-head efficacy … Methods of adverse-events assessment in efficacy trials differed greatly. … , and somnolence were commonly and consistently reported adverse events. … on most serious adverse events is insufficient to draw firm conclusions. … Other Severe Adverse Events The existing evidence on the comparative risk for rare but severe adverse
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
    August 01, 2015 - The present review assessed the comparative effectiveness and adverse effects of 3DCRT, IMRT, SBRT, … This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … Summary of Key Findings and Strength of Evidence for the Benefits and Adverse Effects of Radiotherapy … 3DCRT, SBRT, and PBT: �– In achieving tumor control and improving patient survival �– In reducing adverse … risk of xerostomia might be reduced with the use of IMRT versus 3DCRT �� The potential long-term adverse
  6. effectivehealthcare.ahrq.gov/products/high-risk-drugs/rapid-research
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - This includes: • Overall adverse events. • Specific adverse events. … • Withdrawals and time to withdrawal due to adverse events. … • Persistence and reversibility of adverse events. 3. … Twelve studies provided adverse-events data for FGAs versus SGAs. … Adverse events were reported in 36 studies comparing SGAs with placebo.
  8. effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
    June 01, 2021 - Outcomes including efficacy, impact on quality of life and neurocognition, and adverse effects are important … • We did not detect consistent differences in serious adverse events, number of reported adverse … events, adverse events, radiation necrosis, headaches, fatigue, seizure, vomiting. … Risk of bias varied, 25 trials were terminated early and the quality of adverse assessment and reporting … Adverse Events We found no difference in serious adverse events when comparing WBRT plus SRS with
  9. effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
    May 25, 2021 - However, we do provide all rates of key adverse events in the Summary of Findings tables. … We agree that the timing of each adverse event relates to the vaccine and particular adverse event. … Maybe “A limited number of studies included listed adverse events stratified…”. … Peer Reviewer #5 Results p. 36, line 43: States “severe and serious adverse events”. … We pre-specified key adverse events of interest with our technical expert panel.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
    August 01, 2017 - review that evaluated current evidence regarding the effectiveness, comparative effectiveness, and adverse … The systematic review assessed the efficacy, comparative effectiveness, and adverse effects of a broad … Psychological and Behavioral Therapy: Adverse Effects �� Evidence was insufficient regarding the adverse … Pharmacological Therapy: Adverse Effects (See Table 3) �� Evidence regarding the long-term (more than … and fractures, head injuries, dementia, and cancer. �� FDA labels warn of several potential severe adverse
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - effects • Depression-related outcomes – – • • Adverse effects of treatments Weight … effects 1 study RCT Unknown Imprecisea No difference, findings not reported by specific adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; HR=hazard ratio; MACE=major adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; HR=hazard ratio; MACE=major adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; MACE=major adverse cardiovascular
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - events and may include common adverse events or other adverse events important to clinicians and patients … adverse event,” or “any serious adverse event”; rather, the reports generally focused on specific adverse … “serious adverse events” or “withdrawal due to adverse events,” particularly when evaluating head-to-head … 4) Are there general (non-specific) harms (e.g., any adverse event, any serious adverse event, withdrawal … Are there general (non-specific) harms (e.g., any adverse event, any serious adverse event, withdrawal
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
    May 29, 2025 - $events,$withdrawals$due$to$adverse$events,$serious$adverse$ events$reported,$withdrawal$rates,$switch … $$ Click$here$to$enter$text.$ ( Withdrawals$due$to$adverse$events$$ ! … &ACEI&or&ARB)& treatment$led$to$a$similar$number$of$adverse$ $ events$and$serious$adverse$events.$& … $Moreover,$aliskiren$and$ARB$treatment$led$to$a$similar$number$of$adverse$events,$severe$adverse$events … ,$and$withdrawal$due$to$ adverse$events.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Outcomes: Disorder-specific and -nonspecific adverse events: 1) Overall adverse events. 2) Specific … adverse events: a. … withdrawal because of adverse events, and persistence and reversibility of adverse events … For questions about adverse effects, we will search the U.S. … a dose- related adverse-event analysis.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, … switch rates) o Specific adverse events (including, but not limited to, weight gain, impaired renal … events •Withdrawals due to adverse events •Serious adverse events reported •Withdrawal rates •Switch … Also, adverse events (including, but not limited to, weight gain, impaired renal function, angioedema … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, switch
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - Brief Summary of Findings for Clinicians KEY CLINICAL ISSUE What are the relative effectiveness and adverse … This trial also sought to compare the adverse effects of epidural injections of glucocorticoids plus … There were no differences be- tween injection approaches at 6 weeks. »» There were more reported adverse … Serious adverse events (hospitalization or surgery) were rare among all patients. »» There were higher … Furthermore, the potential adverse effects of systemic glucocor- ticoids (e.g., elevated blood glucose
  17. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
    March 01, 2022 - Serious adverse events are more common in patients who received lasmiditan than placebo. … Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … pharmacologic therapy for acute pain, including any adverse event, study withdrawal due to adverse … Large increases in withdrawal due to adverse events were seen with oxcarbazepine.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - Adverse effects of interest include but are not limited to nausea, diarrhea, headache, tremor, daytime … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. IV. … events Withdrawals because of adverse events Discontinuation rates because of adverse events … Serious adverse events Specific adverse events or withdrawals because of specific adverse events
  19. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - To date, no study has evaluated proximal clinical measures, long-term effects, and adverse events among … Gastrointestinal adverse events/problems. … Metformin monotherapy was associated with more frequent adverse events compared with the combination … , and consistently report all adverse events (not using aggregated events). … medications in withdrawals due to unspecified adverse events. events 4&5k.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
    March 23, 2019 - events o Maternal  Serious maternal adverse events* • “Serious” adverse events (including those … events* o Fetal/infant  Serious fetal/infant adverse events* • “Serious” adverse events (including … events o Maternal  Serious maternal adverse events* • “Serious” adverse events (including those … events* o Fetal/infant  Serious fetal/infant adverse events* • “Serious” adverse events (including … ) due to neonatal/infant adverse events.

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