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Showing results for "adverse".

  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
    January 01, 2007 - What are the potential adverse effects and/or complications involved with off-label prescribing of atypical … Table B summarizes findings on adverse events and safety. … See “Potential adverse effects and complications” section. … Potential adverse effects and complications There is high-quality evidence that olanzapine patients … The manufacturers of risperidone pooled four RCTs and found that cerebrovascular adverse events were
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
    June 01, 2018 - stay in hospital  Length of stay in skilled nursing facility  Sitter use  Hospice enrollment o Adverse … • For outcomes other than adverse events, we will exclude studies that do not have a comparison … stay in hospital; length of stay in skilled nursing facility; sitter use; hospice enrollment) o Adverse … • For adverse events, we will include randomized controlled trials, non- randomized controlled trials … 11 important for each of the patient groups, with at least 1 outcome being a potential adverse
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
    April 01, 2013 - KQ 6: What adverse events are associated with interventions for children exposed to maltreatment (e.g … KQ 6 summarizes the evidence for the one trial that was identified that addressed adverse events. … examining adverse events because there is the potential for harms, even temporary, associated with … Only two trials reported an incident that the authors classified as an adverse event. … The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998 May;14(4):245-58.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
    March 25, 2012 - What are the significant agent-specific harms/adverse effects of nonhormone therapies? … Question 4 Does effectiveness and adverse effects vary among subgroups of patients defined by … Also considered are consequential adverse effects among women using hormone therapies; these adverse … Finally, adverse events accompanying the use of nonhormone agents are also depicted. … ((((“adverse effects” [Subheading]) OR “complications” [Subheading]) OR ( “poisoning” [Subheading] OR
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - systemic therapies may be effective but can be associated with significant short-term and long-term adverse … Currently, guidelines suggest that clinicians balance individual patient characteristics with the reported adverse … Health Assessment Questionnaire Disability Index; HRQoL = health-related quality of life; MACE = major adverse … health outcomes, adequate study duration with clinically relevant treatment modalities, assessment of adverseAdverse events were not evaluated in these studies.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
    January 01, 2008 - the cost of treatment, the severity of diseases that HSCT is used to treat, and the prevalence of adverse
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
    January 01, 2009 - any commonly used dietary supplements decrease the effectiveness of these medications or increase adverse
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
    April 01, 2015 - What are the harms, including adverse events, associated with interventions for management of postpartum … Also, adverse events may occur at any point after the intervention is received. Figure A. … A fourth review noted more adverse effects related to misoprostol than placebo. … No serious adverse reactions were attributed to the study drugs in either RCT but reporting in 1 RCT … Therefore, it is sometimes hard to know whether to classify transfusion as an adverse outcome.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - What are the significant agent-specific harms/adverse effects of nonhormone therapies? … Question 4 Does effectiveness and adverse effects vary among subgroups of patients defined by … Also considered are consequential adverse effects among women using hormone therapies; these adverse … Finally, adverse events accompanying the use of nonhormone agents are also depicted. … ((((“adverse effects” [Subheading]) OR “complications” [Subheading]) OR ( “poisoning” [Subheading] OR
  10. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
    December 04, 2015 - Neuroleptic malignant syndrome is a rare but serious adverse effect. … Adverse effects (AEs) will be examined for each condition (KQ2) and across all conditions (KQ3). … adverse!effects*!! •! Mortality •! Cerebrovascular disease-related events •! … adverse!effects!! •! Neuromotor effects (e.g., extrapyramidal symptoms! … Adverse!event!outcome!data!for!extraction!in!the!comparative!effectiveness!review! Adverse!event!
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
    February 01, 2014 - pharmacologic aids may limit the exposure to tobacco smoke, little is known about their potential adverse … as well as varenicline and bupropion, are category C medications, meaning animal studies have shown adverse … Data on harms or adverse effects of included interventions are captured in Key Question 3. … None of the studies reported a higher incidence of adverse events in women receiving interventions … Smoking and smoking cessation during early pregnancy and its effect on adverse pregnancy outcomes and
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - Further, antipsychotic medications have limited evidence for efficacy and high risk for adverse effects … One can use case series, but they have no controls and may overestimate the rate of “adverse events” … since the rate of “adverse events” among persons getting placebos is high.40 One can use case-control … One can examine adverse events with the intervention in other patient populations, but this does not … Placebo--efficacy and adverse effects in controlled clinical trials.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
    October 01, 2015 - The most common adverse reactions reported in patients treated with pirfenidone included abdominal … patients may require a dose reduction to 100 mg, twice daily, or treatment interruption to manage adverse … The most common adverse reactions reported in patients treated with nintedanib included abdominal pain … impact potential, more data demonstrating reductions in transplantation-associated complications, adverse … However, two clinical experts stated that adverse events could reduce patient acceptance.58,64 One
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
    March 01, 2012 - Impugning the integrity of medical science: the adverse effects of industry influence. … On reporting: • Were any patients excluded from the adverse effects analysis? … • Which categories of adverse effects were reported by the investigators? … • Is there a plausible biological mechanism linking the intervention to the adverse event? … Adverse effects. In: Higgins JPT, Green S, eds.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
    May 27, 2010 - Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect … of the challenges of conducting randomized, controlled trials of IMRT to address non-xerostomia adverse … of the challenges of conducting randomized, controlled trials of IMRT to address non-xerostomia adverse … Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect … • CTCAE is a broad dictionary of adverse event terms and grades.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
    March 13, 2012 - none • Final outcomes: diagnosis of ovarian cancer, ovarian cancer mortality, overall mortality • Adverse … certain short-term (e.g., venous thromboembolism) and long-term (e.g., breast cancer, cervical cancer) adverse … : For KQs 1, 2, 3, 6: o Final outcomes: diagnosis of ovarian cancer, ovarian cancer mortality o Adverse … cancer, endometriosis, dysmenorrhea, acne, colorectal cancer, or premenstrual dysphoric disorder o Adverse … The safety outcomes will be framed to help identify adverse events as described in KQ 5.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research-2007.pdf
    January 01, 2007 - events or potential adverse events. … of medications or on cost- savings,5, 8, 9 while other programs have focused on reducing potential adverse … Fatal adverse drug events: the paradox of drug treatment. J Intern Med 2001;250(4):327-41. 19. … Adverse drug events in emergency department patients. … Role of pharmacist counseling in preventing adverse drug events after hospitalization.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - study and 0.49 percent (1/205) in another study; one study reported one case of a life-threatening adverse … Although six studies reported low rates (0 to 1.2%) of death or serious adverse events among patients … to treatment for opioid use disorder and risk of future overdose episodes, in addition to serious adverse … were probably at low risk for such events, and there is insufficient evidence to determine risk of adverseAdverse events after naloxone treatment of episodes of suspected acute opioid overdose.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
    December 01, 2014 - What is the comparative effectiveness of 3DCRT, IMRT, SBRT, and PBT regarding adverse events and QOL … Outcomes Outcomes for Key Questions 1, 3, and 4 included— • Final outcomes: QOL and adverse events, … Criteria for Adverse Events) is necessary to permit accurate assessment of the relative benefits and … In particular, given the evidence summarized in this report, we recognize dysphagia as a key adverse … Evidence was insufficient to draw relative conclusions on survival or tumor control; adverse events
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
    February 19, 2010 - Outcomes: The outcomes are broken up into adverse events (e.g., failure to deploy the device or remove … Adverse events, harms and safety issues reported Question 3: What are the variables associated with … The outcomes are broken up into adverse events, intermediate outcomes, and final health outcomes. … The adverse events of note include failure of the device to employ, breakage or fracture, perforation … outcomes  Mortality  mRS  NIHSS  Barthel Index  GOS Patients with Acute Ischemic Stroke Adverse

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