-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - visits and hospitalizations, quality of life, missed school or work, preventive treatment-
related adverse … events, imaging-related adverse events, serious adverse events,
discontinuations due to adverse events … visits and
hospitalizations, quality of life, missed school or work,
preventive treatment-related adverse … events, imaging-
related adverse events, serious adverse events,
discontinuations due to adverse events … stone events (e.g., urinary
obstruction, infection)
Quality of life
Serious treatment-
related adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - children < 6 years of age with ADHD or Disruptive Behavior
Disorder, what are the effectiveness and adverse … Among people 6 years of age or older with ADHD, what are the
effectiveness and adverse event outcomes … • Descriptive Statistics
Outcomes Numerical or statistical
results of any
effectiveness or adverse … event outcomes
Numerical or statistical
results of any
effectiveness or adverse
event outcomes … sociodemographic
characteristics
time period
Diagnosis of
ADHD (any age)
(KQ 1)
(KQ 2)
Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
January 01, 2020 - • Adverse effects of approaches including burden of approach,
nutritional deficiencies or eating … disorders, activity related injuries
including fracture, and adverse events of medications (e.g., diarrhea … • For intermediate outcomes, adverse effects and quality of life,
additional time points of interest … effect of
medication
• Other adverse effects
Interventions
Self-management (KQ
1), Dietary … • Obesity-related clinical outcomes, intermediate outcomes,
adverse effects and quality of life
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
January 01, 2022 - Adverse Events
Table E-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Cannabis RCTs adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F1-4.xlsx
January 01, 2022 - Adverse Events
Table F-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Adverse Event (Denominator) Intervention B, % With Withdrawals Due to Adverse Event Intervention A,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
January 01, 2011 - because ESAs are very expensive, but also because
higher dosing regimens of ESA are associated with adverse … What are the adverse effects or harms associated with testing using newer and/or older
markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of
iron status … o Adverse effects or harms associated with testing and associated treatments (e.g., test-
related anxiety … events
related to lab
testing
Adverse events
related to
management
strategies
KQ1
KQ
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - Research indicates that individuals can reduce their risk of obesity-related adverse health conditions … While several experts mentioned the uncertainty of long-term adverse
events as a potential barrier … The potential was tempered by experts’ significant concerns about
reported adverse events. … However, multiple experts also noted the significant reported side effects and adverse
events and the … discontinuation rate, which they believe to be significant adverse factors.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - ill patients may not account for these factors, placing these patients at
risk of treatment failure, adverse … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … Question 3
Does the evidence for morbidity, mortality, antibiotic-related adverse events, clinical … or
prospective cohort studies with an
eligible comparison group
• For KQ 1c, KQ 2c, and KQ 3:
adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
May 15, 2017 - a low level of
evidence.13 Treating to target includes regular monitoring of disease activity and adverse … We will also examine
comparative harms of drug therapies in terms of tolerability, adherence, and adverse … For patients with early RA, do drug therapies differ in harms, tolerability, patient
adherence, or adverse … Early
Rheumatoid
Arthritis
Intermediate outcomes
• Disease activity
• Joint damage
• Remission
Adverse … effects, risk of serious adverse
effects, specific adverse effects, patient adherence
All other outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - However, adverse
events, especially irritability and moodiness, can lead to discontinuation, and use … Few serious adverse events were noted. … Fewer
individuals discontinue psychostimulants and ATX than guanfacine XR due to adverse events. … We have identified key clinical and adverse events outcomes
as reported in the draft review, which is … Among individuals ages 6 years or older with ADHD, what are the adverse events and
noncompliance rates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
January 01, 2014 - services include providing education and counseling, improving medication adherence, and
detecting adverse … Populations
Medication misuse and poor medication adherence commonly contribute to adverse events … still
other MTM services relate to patient-centered outcomes (e.g., morbidity, mortality, reduced
adverse … that can
be simplified with same therapeutic benefit; and potential for drug-drug interactions
or adverse … Disease-specific or all-cause mortality, including fall-related mortality
Reduced (actual) adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - Study withdrawals due to adverse effects were more
common (though not statistically so) with dopamine … Differences were primarily due to an increase in withdrawals related to
adverse effects (application … More
patients randomized to dopamine agonist had at least one adverse effect compared with placebo … Short-term adverse effects from treatment with dopamine agonists
compared with placebo were nausea, … Differences were primarily due to an increase in withdrawals related to adverse effects
(application
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - Adverse clinical outcomes associated with
OSA include: cardiovascular disease,
hypertension, non-insulin-dependent … quality of life or
death), intermediate or surrogate outcomes (such as
laboratory measurements), and adverse … to
cardiovascular disease, diabetes, motor vehicle
accidents, and other causes represent important adverse … All interventions have the potential for adverse events. … No adverse event with potentially long-
term consequences was reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - embolization / non-target
tissue embolization
• Ovarian failure
• Other serious adverse … Analytic Framework
The analytic framework illustrates the population, interventions, outcomes, and adverse … one or more:
o Uterine fibroid treatment/intervention outcome (KQs 1, 2)
o Harm or adverse … effects"[Mesh]) OR "Uterine Myomectomy/adverse
effects"[MeSH] OR morcellat*
1251
#5 … ("Electrosurgery/adverse effects"[Mesh] AND uterine) OR "Uterine Myomectomy/adverse
effects"[
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
December 01, 2015 - adverse events, flu-like symptoms, rash)
Intermediate outcomes
•! … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events. … Found no difference in
withdrawals due to adverse
events. … No difference in risk of
withdrawal due to adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
December 01, 2015 - adverse events, flu-like symptoms, rash)
Intermediate outcomes
•! … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events. … Found no difference in
withdrawals due to adverse
events. … No difference in risk of
withdrawal due to adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - However, both surgical and radiation treatments
result in significant short- and long-term adverse … Thus, all men who undergo treatment
risk suffering the adverse events of the treatment, while only … mortality, incidence of metastatic disease, quality
of life, morbidity from primary treatment, other adverse … Randomized controlled trials, nonrandomized comparative studies, and cohort
studies; for adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
April 01, 2019 - Do telehealth consultations result in harms,
adverse events, or negative unintended
consequences? … • Adverse effects: Only studies of surgery
explicitly examined harms, but the study
limitations … • Adverse events: No increased harms,
specifically hemorrhage (moderate strength of
evidence). … • Adverse events: No information was available
about harms (insufficient evidence). … Low
Harms (KQ3) 2 Rates of complications and serious adverse events
reported in two studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
July 01, 2012 - i.e., whether as replacement,
triage, or add-on), range of potential clinical utility, and potential adverse … as specific as the old test and the new test
has advantages over the old test such as causing fewer adverse … treatment for undetected cancer when PET is falsely negative
versus the benefits of safely avoiding adverse … of negative predictive values suggest that there is an unfavorable
trade-off between avoiding the adverse … and specific as the old test
and the new test has advantages over the old test such as having fewer adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
December 16, 2011 - Adverse Effects
+
Dopaminergic
agents
Levodopa Sinemet
®
Nausea or vomiting;
orthostatic … Eliminating RLS precipitants (caffeine, alcohol, and nicotine; antidepressants; antihistamines)
†Adverse … Harms
specific to each class of drugs are listed in Table 1)
o Treatment discontinuation due to adverse … effects (number of patients
experiencing adverse events, number of drop-outs due to adverse events … We will assess the number and percentage of patients that
report adverse effects, especially augmentation