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Total Results: 1,401 records

Showing results for "adverse".

421. Cer-250-Cannabis-Tables-E1-E4-2022-Update 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
     January 01, 2022 - Adverse Events Table E-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … to Adverse Event (Denominator) Intervention A, % With Withdrawals Due to Adverse Event Intervention B … Cannabis RCTs adverse events

422. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
     August 10, 2010 - children < 6 years of age with ADHD or Disruptive Behavior Disorder, what are the effectiveness and adverse … Among people 6 years of age or older with ADHD, what are the effectiveness and adverse event outcomes … • Descriptive Statistics Outcomes  Numerical or statistical results of any effectiveness or adverse … event outcomes  Numerical or statistical results of any effectiveness or adverse event outcomes … sociodemographic characteristics  time period Diagnosis of ADHD (any age) (KQ 1) (KQ 2) Adverse

423. High-Cholestorol-Medicines-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
     February 01, 2014 - intensive lipid-modifying therapy, what are the comparative long-term benefits and rates of serious adverse … for the following outcomes: mortality, acute coronary events, revascularization procedures, serious adverse … Included adherence and harms outcomes—adherence, serious adverse events (as reported by investigators … ), withdrawal due to adverse events, cancer, elevated liver transaminases, adverse +musculoskeletal … bile acid sequestrant and statin to intensification of statin monotherapy on the rates of serious adverse

424. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
     January 01, 2011 - because ESAs are very expensive, but also because higher dosing regimens of ESA are associated with adverse … What are the adverse effects or harms associated with testing using newer and/or older markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of iron status … o Adverse effects or harms associated with testing and associated treatments (e.g., test- related anxiety … events related to lab testing Adverse events related to management strategies KQ1 KQ

425. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - Research indicates that individuals can reduce their risk of obesity-related adverse health conditions … While several experts mentioned the uncertainty of long-term adverse events as a potential barrier … The potential was tempered by experts’ significant concerns about reported adverse events. … However, multiple experts also noted the significant reported side effects and adverse events and the … discontinuation rate, which they believe to be significant adverse factors.

426. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - ill patients may not account for these factors, placing these patients at risk of treatment failure, adverse … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … Question 3 Does the evidence for morbidity, mortality, antibiotic-related adverse events, clinical … or prospective cohort studies with an eligible comparison group • For KQ 1c, KQ 2c, and KQ 3: adverse

427. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - a low level of evidence.13 Treating to target includes regular monitoring of disease activity and adverse … We will also examine comparative harms of drug therapies in terms of tolerability, adherence, and adverse … For patients with early RA, do drug therapies differ in harms, tolerability, patient adherence, or adverse … Early Rheumatoid Arthritis Intermediate outcomes • Disease activity • Joint damage • Remission Adverse … effects, risk of serious adverse effects, specific adverse effects, patient adherence All other outcomes

428. Future Research Needs for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers, Long-Term Effectiveness in All Ages, and Variability in Prevalence, Diagnosis, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
     May 01, 2012 - However, adverse events, especially irritability and moodiness, can lead to discontinuation, and use … Few serious adverse events were noted. … Fewer individuals discontinue psychostimulants and ATX than guanfacine XR due to adverse events. … We have identified key clinical and adverse events outcomes as reported in the draft review, which is … Among individuals ages 6 years or older with ADHD, what are the adverse events and noncompliance rates

429. Medication-Therapy-Management Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
     January 01, 2014 - services include providing education and counseling, improving medication adherence, and detecting adverse … Populations Medication misuse and poor medication adherence commonly contribute to adverse events … still other MTM services relate to patient-centered outcomes (e.g., morbidity, mortality, reduced adverse … that can be simplified with same therapeutic benefit; and potential for drug-drug interactions or adverse …  Disease-specific or all-cause mortality, including fall-related mortality  Reduced (actual) adverse

430. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
     July 01, 2011 - Adverse clinical outcomes associated with OSA include: cardiovascular disease, hypertension, non-insulin-dependent … quality of life or death), intermediate or surrogate outcomes (such as laboratory measurements), and adverse … to cardiovascular disease, diabetes, motor vehicle accidents, and other causes represent important adverse … All interventions have the potential for adverse events. … No adverse event with potentially long- term consequences was reported.

431. Treatment for Restless Legs Syndrome: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
     February 01, 2013 - Study withdrawals due to adverse effects were more common (though not statistically so) with dopamine … Differences were primarily due to an increase in withdrawals related to adverse effects (application … More patients randomized to dopamine agonist had at least one adverse effect compared with placebo … Short-term adverse effects from treatment with dopamine agonists compared with placebo were nausea, … Differences were primarily due to an increase in withdrawals related to adverse effects (application

432. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 -  embolization  /  non-­target   tissue  embolization   •   Ovarian  failure   •   Other  serious  adverse … Analytic Framework The analytic framework illustrates the population, interventions, outcomes, and adverse … one  or  more:   o  Uterine  fibroid  treatment/intervention  outcome  (KQs  1,  2)     o  Harm  or  adverse …  effects"[Mesh])  OR  "Uterine  Myomectomy/adverse   effects"[MeSH]  OR  morcellat*   1251   #5   … ("Electrosurgery/adverse  effects"[Mesh]  AND  uterine)  OR  "Uterine  Myomectomy/adverse   effects"[

433. Evidence Summary Comparative Effectiveness Review 216 Telehealth for Acute and Chronic Care Consultations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
     April 01, 2019 - Do telehealth consultations result in harms, adverse events, or negative unintended consequences? … • Adverse effects: Only studies of surgery explicitly examined harms, but the study limitations … • Adverse events: No increased harms, specifically hemorrhage (moderate strength of evidence). … • Adverse events: No information was available about harms (insufficient evidence). … Low Harms (KQ3) 2 Rates of complications and serious adverse events reported in two studies.

434. Evidence-based Practice Center Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
     May 19, 2011 - However, both surgical and radiation treatments result in significant short- and long-term adverse … Thus, all men who undergo treatment risk suffering the adverse events of the treatment, while only … mortality, incidence of metastatic disease, quality of life, morbidity from primary treatment, other adverse … Randomized controlled trials, nonrandomized comparative studies, and cohort studies; for adverse events

435. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - adverse events, flu-like symptoms, rash) Intermediate outcomes •! … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events. … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events.

436. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - adverse events, flu-like symptoms, rash) Intermediate outcomes •! … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events. … Found no difference in withdrawals due to adverse events. … No difference in risk of withdrawal due to adverse events.

437. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - Fractures w ere not prespecif ied as an outcome and w ere captured via routine adverse event reporting … Statements about the risk of potential adverse drug reactions are made without the rigor that is applied … In a clinical trial all adverse events are collected without regard to the investigator’s assessment … is associated with a higher (harm) or lower (benefit) risk of a specific adverse event. … Evidence on fracture incidence, change in bone mineral density (BMD), and adverse events over up to

438. Methods Guide for Medical Test Reviews Chapter 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
     July 01, 2012 - i.e., whether as replacement, triage, or add-on), range of potential clinical utility, and potential adverse … as specific as the old test and the new test has advantages over the old test such as causing fewer adverse … treatment for undetected cancer when PET is falsely negative versus the benefits of safely avoiding adverse … of negative predictive values suggest that there is an unfavorable trade-off between avoiding the adverse … and specific as the old test and the new test has advantages over the old test such as having fewer adverse

439. Topic-Brief2-Opioid-Withdrawal (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
     April 01, 2021 - Patients may experience withdrawal symptoms, negative psychological effects, worsened pain, or serious adverse … population could improve symptoms and increase the likelihood of tapering success, while reducing adverse … opioid therapy is associated with reduced pain intensity in some patients, it is also associated with adverse … function, quality of life, mental health outcomes, opioid dose, likelihood of opioid discontinuation, adverse … challenge for clinicians and patients and can be associated with negative clinical outcomes and adverse

440. Topic-Brief2-Opioid-Withdrawal (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
     April 01, 2021 - Patients may experience withdrawal symptoms, negative psychological effects, worsened pain, or serious adverse … population could improve symptoms and increase the likelihood of tapering success, while reducing adverse … opioid therapy is associated with reduced pain intensity in some patients, it is also associated with adverse … function, quality of life, mental health outcomes, opioid dose, likelihood of opioid discontinuation, adverse … challenge for clinicians and patients and can be associated with negative clinical outcomes and adverse