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effectivehealthcare.ahrq.gov/products/cardio-dental/research
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effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Pollock, MD*
Background: Adverse drug events (ADEs) are an important cause
of patient injury. … Adverse drug event data collection, National Elec-
tronic Injury Surveillance System-Cooperative Adverse … The FDA safety information and adverse event reporting
program. … How the US Food and Drug Administration defines and
detects adverse drug events. … Incidence of adverse drug events
and potential adverse drug events. Implications for prevention.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
October 01, 2015 - Adverse Effects: Tests
We included seven studies that evaluated adverse effects of
various tests for … Adverse Effects: Treatments
This Key Question addressed adverse effects of various
treatments, including … events (SOE: low
for local adverse events; insufficient for systemic
adverse events). … MMC:
Systemic adverse
events
Low BCG was associated with increased risk of any
systemic adverse event … gemcitabine:
Systemic adverse
events
Low There were no differences in systemic adverse
events (1
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - In children with JIA, do the rate
and type of adverse events differ between:
a. … The rate and type of adverse events did not differ
between treatment groups in these studies. … comparisons of the rate and type of adverse events
among the various DMARDs. … • Reporting of adverse events. … Few high-quality data are available regarding the
adverse events associated with DMARDs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - There was no
increase in risk of serious adverse events or withdrawal due to adverse events. … Some nonopioid treatments had frequent overall adverse events and some less frequent
yet serious adverse … effects, while nonpharmacological treatments typically reported few
adverse events.10
Cannabinoids … Other prioritized adverse
events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … The evidence on adverse events with
cannabis-related products is much less robust than the evidence
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - The direct
adverse events, tolerability, Low (DRI vs. … In the four studies that did report episodes of
ARB) angioedema, this adverse event was observed only … event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, and … events, withdrawals due to adverse events, serious adverse events reported,
withdrawal rates, and switch … rates], as the latter may or may not be due to identifiable adverse events.)
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - Also, ACEIs are associated with
well-known adverse events not shared by ARBs,
including cough (estimated … For adult patients with essential
hypertension, how do ACEIs and ARBs differ in safety,4
adverse events … events,
withdrawals due to adverse events, serious adverse events reported,
withdrawal rates, and switch … For RCTs, this translates to a difference in rates
safety, adverse events, tolerability, to Moderate … There was no evidence of
differences in rates of other commonly reported specific
adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - specific adverse events. … Key Findings
Overall
• Adverse effects assessed by withdrawals and
withdrawals due to adverse effects … The two trials that reported specific adverse events
reported no individual adverse event in more than … (e.g., any,
serious adverse effects, adverse effects causing withdrawal,
predefined specific adverse … conditions as
well as any adverse events, serious adverse events, adverse
events causing withdrawal
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
January 01, 2020 - In
the results section, each table of adverse events is labeled
‘reported adverse events.’ … Line 33- How are serious
adverse events defined? … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events,” rather … The study collected
only serious adverse events. … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events” rather
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effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - ORIGINAL ARTICLE
Real-Time Vaccine Safety Surveillance for the Early
Detection of Adverse Events
Tracy … events, hold promise
to allow earlier identification of adverse events. … Active surveillance of vaccine
safety: a system to detect early signs of adverse events. … Poisson sequential sampling modified towards maximal safety in
adverse event monitoring. … Prompt, active, population-based identification of adverse drug
reaction signals.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
August 06, 2018 - Effects"] or [mh
/AE,CI,DE,MO,PO,TO] or adverse effect*:ti,ab or adverse event*:ti,ab or
adverse … reaction*:ti,ab or "adverse outcome":ti,ab or "adverse outcomes":ti,ab
or [mh "Adverse Drug Reaction … Effects" OR TX
“adverse effect” or TX “adverse event” OR TX “adverse
events” OR TX "adverse outcome … Effects"] or [mh
/AE,CI,DE,MO,PO,TO] or adverse effect*:ti,ab or adverse event*:ti,ab or
adverse … Effects" OR
TX “adverse effect” or TX “adverse event” OR
TX “adverse events” OR TX "adverse
outcome
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - Events of
Interest
Adverse Events Depression treatment-related adverse events. … The adverse events measure also required a modification to capture adverse events related to
procedures … Additional
procedure codes were added to the Adverse Event value sets. … Potential challenges related to the
availability of PHQ-9, adverse event, suicide, and mortality data … Adverse Events Data
The intent of the adverse events measure is to capture all adverse events related
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - The
intranasal route was common in studies reporting adverse
events for the comparison of opioids versus … Analytic framework
Abbreviations: AE=adverse event; KQ=Key Question
Data Sources
We searched MEDLINE … Opioids may cause fewer adverse events than
ketamine, primarily administered IN. … Opioids may cause
more adverse events than NSAIDs, administered
primarily IV. … evidence suggests that opioids may
cause fewer total adverse events than ketamine.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - Harms are Adverse Events or
Complications
• Definition of harms:
► Adverse events or complications … What is a Serious Adverse Event? … What is a Serious Adverse Event? … Consider Composite
Adverse Events (II)
• “Serious adverse events” or “withdrawal due to
adverse events … Consider Composite Adverse Events (I)
6. Consider Composite Adverse Events (II)
7.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Response Protocol
Project Title: Making Healthcare Safer IV:
Protocols for High-Risk Drugs: Reducing Adverse … The “Protocols for High-Risk Drugs:
Reducing Adverse Drug Events Related to Anticoagulants” as a patient … effects (e.g., bleeding).7,8 The 2019 National Action Plan for Adverse Drug Event
Prevention (ADE … US
Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. … Advancing Medication
Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - due to adverse events;
4) Persistence and reversibility of adverse events. … events, withdrawal due to adverse events, persistence
and reversibility of adverse events. … due to adverse events, and persistence and reversibility of adverse
events … Adverse events will be recorded for each intervention group including the description of
the adverse … a dose-adverse
event analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - Serious adverse events are more
common in patients who received lasmiditan than
placebo. … Evidence is insufficient to draw
conclusions about serious adverse events. … Evidence is insufficient to draw
conclusions about serious adverse events. … pharmacologic therapy for acute pain,
including any adverse event, study withdrawal
due to adverse … Large increases in withdrawal due to
adverse events were seen with oxcarbazepine.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disposition-comments.pdf
April 10, 2025 - This underemphasizes the
consistent evidence of positive impact and
overemphasizes the adverse events … However,
pharmacotherapy was associated with an
increased risk of experiencing any adverse
event. … and Discussion sections did not include
a definition of “adverse event”? … Details about the adverse events reported in the
trials can be found in Appendix L. … There were very few adverse events reported in
the psychosocial studies, which makes
comparing adverse