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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
September 20, 2022 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Akgol Gur, 2020 Emergency department … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … Events Adverse Events Withdrawals Due To Adverse Events Sponsor Quality
Cooper, 2021 Outpatient U.S … B
Any adverse event: 52.7% (15/46) vs. 8.8% (3/34), p=0.002
Any severe adverse event: 16.7% (6/36) vs
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effectivehealthcare.ahrq.gov/sites/default/files/draft-appendix-pbt-cohort-studies.xlsx
May 11, 2021 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. … NR
Serious adverse events: none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04)
Withdrawals due to adverse
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effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
January 01, 2011 - set of criteria
(attributes and levels):
• I want the best treatment:
Clinical Outcome
Adverse … Drug B
partial relief
high blood
pressure
3 US$
Drug C
partial relief
No adverse … preference
for the alternatives:
• I want the best treatment:
Clinical Outcome
C1 = 0.5
Adverse … events points to:
• Serious adverse events, which points to :
o Suicide and attempted suicide
o … Other serious adverse events
• Adverse events, which points to:
o Sexual dysfunction
o Other adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - events, withdrawals
because of adverse events, serious adverse events,
specific adverse events (including … because of
adverse events. … of adverse
events. … events,
overall risk of serious adverse events, or discontinuation
due to adverse events. … events, overall
risk of serious adverse events, or discontinuation due to
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - adverse effects of first-line pharmacologic treatments? … effects and comparative adverse effects
of first-line pharmacologic treatments? … Outcomes:
We are interested in the following adverse effects for KQ1 and KQ2:
• Any adverse event … , as in those who experienced an adverse events
• Withdrawal due to adverse events
• Serious adverse … Effects
• Adverse events
• Withdrawal due to adverse
events
• Serious adverse events
• Hospitalization
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - The broader
inclusion criteria for adverse event data take into account that rare adverse events are … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting will also assess whether
adverse events, including serious adverse events, were defined … Number of patients with serious adverse events
2. Number of adverse events
3. … What is a Serious Adverse Event?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - and Epidural Anesthesia:
The evidence is insufficient to understand the effectiveness, benefits, or
adverse … for pain relief, but the data are too limited to draw
conclusions about the benefits or harms. ���
Adverse … Events
Overall, adverse event rates were similar in both treated and control
groups, but studies were … Serious adverse events such as myocardial infarction, stroke,
and renal failure were either rarely reported … For all modalities, the evidence is generally inadequate
to estimate harms and the incidence of adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - Low
Discontinuation rates and severe adverse events
higher with infliximab. … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in adverse events in efficacy studies. … Low
No differences in serious adverse events between
groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-q3-tables-f5.xlsx
June 15, 2021 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. … NR
Serious adverse events: none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04)
Withdrawals due to adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - There was no
increase in risk of serious adverse events or withdrawal due to adverse events. … Some nonopioid treatments had frequent overall adverse events and some less frequent
yet serious adverse … effects, while nonpharmacological treatments typically reported few
adverse events.10
Cannabinoids … Other prioritized adverse
events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … The evidence on adverse events with
cannabis-related products is much less robust than the evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Pollock, MD*
Background: Adverse drug events (ADEs) are an important cause
of patient injury. … Adverse drug event data collection, National Elec-
tronic Injury Surveillance System-Cooperative Adverse … The FDA safety information and adverse event reporting
program. … How the US Food and Drug Administration defines and
detects adverse drug events. … Incidence of adverse drug events
and potential adverse drug events. Implications for prevention.
-
effectivehealthcare.ahrq.gov/products/migraine-prevention/research-2013
April 18, 2013 - effects, and 26 (95% CI, 10 to 43) would discontinue treatments due to bothersome adverse effects. … Adverse effects leading to treatment discontinuation were examined in 68 RCTs. … effects and treatment discontinuation due to adverse effects. … For episodic migraine, approved drugs are effective but increase risk of adverse effects and treatment … discontinuation due to adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
October 01, 2015 - Adverse Effects: Tests
We included seven studies that evaluated adverse effects of
various tests for … Adverse Effects: Treatments
This Key Question addressed adverse effects of various
treatments, including … events (SOE: low
for local adverse events; insufficient for systemic
adverse events). … MMC:
Systemic adverse
events
Low BCG was associated with increased risk of any
systemic adverse event … gemcitabine:
Systemic adverse
events
Low There were no differences in systemic adverse
events (1
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - See Key Question 3 on
adverse events. … (Low) Mixed results for specific adverse
events. … (Low) Mixed results for specific
adverse events. … (Low)
Mixed results for specific adverse events. … (Low) Mixed results
for specific adverse events.
-
effectivehealthcare.ahrq.gov/products/radiation-brain-metastases/protocol
January 28, 2020 - The broader inclusion criteria for adverse event data take into account that rare adverse events are … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting will also assess whether adverse events, including serious adverse events, were defined … We will use the authors' classification of serious adverse events. … events)
Number of patients with serious adverse events
Number of adverse events
Any specific adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_disposition-comments.pdf
January 01, 2020 - In
the results section, each table of adverse events is labeled
‘reported adverse events.’ … Line 33- How are serious
adverse events defined? … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events,” rather … The study collected
only serious adverse events. … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events” rather
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
January 01, 2020 - In
the results section, each table of adverse events is labeled
‘reported adverse events.’ … Line 33- How are serious
adverse events defined? … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events,” rather … The study collected
only serious adverse events. … events,” “systemic adverse
events,” “one or more adverse events” or “serious adverse
events” rather
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - In children with JIA, do the rate
and type of adverse events differ between:
a. … The rate and type of adverse events did not differ
between treatment groups in these studies. … comparisons of the rate and type of adverse events
among the various DMARDs. … • Reporting of adverse events. … Few high-quality data are available regarding the
adverse events associated with DMARDs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - Also, ACEIs are associated with
well-known adverse events not shared by ARBs,
including cough (estimated … For adult patients with essential
hypertension, how do ACEIs and ARBs differ in safety,4
adverse events … events,
withdrawals due to adverse events, serious adverse events reported,
withdrawal rates, and switch … For RCTs, this translates to a difference in rates
safety, adverse events, tolerability, to Moderate … There was no evidence of
differences in rates of other commonly reported specific
adverse events.