-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - , withdrawal
due to adverse events)? … events
o Serious adverse events (composite outcome)c
o Neurologic adverse events (e.g., neuropathy … events
o Other reported important clinical adverse events
• Organ toxicity
o Liver (aspartate … events (composite outcome—FDA definition of serious adverse events24),
withdrawal due to adverse … What is a Serious Adverse Event? Updated December
15, 2010.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
May 29, 2025 - suited for testing hypotheses of whether one intervention is associated with a greater risk for an adverse … are well suited for testing hypotheses that one intervention is associated with a greater risk for an adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
May 29, 2025 - suited for testing hypotheses of whether one intervention is associated with a greater risk for an adverse … are well suited for testing hypotheses that one intervention is associated with a greater risk for an adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
January 01, 2013 - What are the adverse effects or harms associated with testing using newer and/or older
markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of
iron status? … What are the adverse
effects or harms associated with
testing using newer and/or older
markers of … What are the adverse effects
or harms associated with the
treatments guided by tests of iron
status … 5 What is the best biomarker to monitor iron overload as an adverse event resulting from treatment of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - • For Key Question 3, conclusions regarding other adverse events
are possibly out of date. … The rates of GI adverse effects were similar
for thiazolidinediones and sulfonylureas. … Metformin was associated with more frequent
GI adverse events than were DPP-4 inhibitors. … Adverse event rates were comparable across treatment arms. … Incidences of adverse effects were comparable between groups, with no
increases in hypoglycemia.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - Withdrawals due to adverse events were below
10% in all treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common lorcaserin-related
adverse events. U.S. … Common adverse events were
headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - , what are the comparative harms of
HSCT, ERT, and substrate reduction with iminosugars
regarding adverse … harms of HSCT,
immunosuppressants, targeted biologic therapies, and low-
dose chemotherapy regarding adverse … tumors
HSCT = hematopoietic stem-cell transplantation; KQ = Key Question; QOL = quality of life
Adverse … disease; HSCT = hematopoietic stem-cell transplantation; KQ = Key Question;
QOL = quality of life
Adverse … disease; HSCT = hematopoietic stem-cell transplantation; KQ = Key Question;
QOL = quality of life
Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - continuous
positive airway pressure (CPAP), associated with less morbidity, lower mortality, lower adverse … extubation to NPPV, compared to usual care, associated with less morbidity, lower
mortality, lower adverse … o Adverse effects of interventions (KQs 1–4):
Rates of:
– Aspiration
– Secondary infections … The safety outcomes will be framed to help
identify adverse events, including aspiration, secondary … events; and
intermediate, final, and adverse events outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
July 09, 2024 - Caregiver or family outcomes
(including caregiver health and
quality of life)
Harm outcomes:
Adverse … Preliminary Analytic Framework
Adverse effects … Intermediate
Outcomes
Treatment
adherence
Lab values
Healthcare
utilization
Adverse … effects of
diagnosis
Adverse effects of
treatment
6
IV. … or "adverse react*" or complication?
-
effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
March 21, 2016 - (pg. 35)
Public Reviewer 3:
Fred Kurtz,
Medtronic
General
comments
Adverse Events Associated … More detail is provided in the
report under adverse effects noted on pg. 30-31
under KQ 2, Surgical … If you are really trying to discuss
ostomy as a surgical adverse event, add ileostomy to
colostomy, … colostomy); negative emotional/psychological
effects; other adverse effect(s) related to
treatment… … Hull 2013 has
been added to Appendix table F9 (KQ 2) of
adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol-amendment.pdf
February 05, 2025 - Caregiver or family outcomes
(including caregiver health and
quality of life)
Harm outcomes:
Adverse … Intermediate
Outcomes
Treatment
adherence
Lab values
Healthcare
utilization
Adverse … effects
of screening Adverse effects of
diagnosis Adverse effects of
treatment … ab.
27 Delivery of Health Care/ or exp Disease Management/ or "Drug-Related Side Effects and
Adverse … or "adverse react*" or complication?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - Possible that different definitions (for adverse events) or scales (for quality of life) and different … Possible that different definitions (for adverse events) or scales (for quality of life) and different … Objective outcomes (e.g., survival, adverse events) were centrally assessed, reducing potential bias. … assessment, and no protocol or statistical analysis plan is available, but standard approach used to assess adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
August 09, 2021 - The review will also provide rates of
adverse events of the various PBI modalities necessary for shared … In adult women with early stage breast cancer, what are the comparative effectiveness,
adverse events … How do the effectiveness, adverse events, and cosmetic outcomes of partial breast
irradiation vary by … In adult women with early stage breast cancer, what are the comparative effectiveness,
adverse events … events (KQ1-2)
Rate of adverse events
(noncomparative series of PBI) (KQ 2a)
Financial toxicity (KQ
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - effects to be considered, such as
distinguishing between treatment discontinuation due to adverse effects … Separate key questions address the
accuracy of screening (KQ 1) and the effectiveness and risk of adverse … effects
• Adverse effects of treatment (excluding clinical
outcomes listed above)
o Weight gain … The safety outcomes will be framed to help identify adverse events, including those
from drug therapies … Definition of Terms
ACS Acute Coronary Syndrome
ACT Acceptance and commitment therapy
AE Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
January 01, 2007 - Adverse events associated with medical and angioplasty treatments of renal artery stenosis in direct … No data on adverse
events in medicine
arm
Webster
199812
55
(55)
Angioplasty (no stent)
vs … Adverse events associated with the medical treatment of renal artery stenosis (no new data)
Author … Adverse events associated with angioplasty with stent placement treatment of renal artery stenosis (new … Adverse events associated with the surgical treatment of renal artery stenosis (no new data)
Author
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - "Increasing statin dose or potency could potentially increase
frequency of important adverse events … The Stein data can also be added to the section “Participants with at least
one adverse event” in the … Information on adverse events was only collected if dichotomous
data were available (number of people … A decline in cellular and physiologic system increases vulnerability to
adverse events of treatment. … - On page D-68, participants experiencing an adverse event, and page D-
85, participants experiencing
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - Moreover, depressive symptoms are
2
associated with adverse parenting practices, including … both medication and disorder,
depending on the volume of evidence and the specificity of the data on adverse … Search ((#10 AND Humans[Mesh:noexp]) OR (#10 NOT Animals[Mesh:noexp])) 4340
#12 Search (accident* OR "Adverse … Effects" OR "adverse effect" or "adverse event"
OR "adverse events" OR "adverse outcome" OR "adverse … outcomes" OR "adverse
reaction" OR "adverse reactions" OR "chemically induced" OR complication* OR
-
effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
April 01, 2020 - events, and no differences between comparison
groups in frequency of intervention-related
adverse … Table 64 in the full
report summarizes reported adverse events for
each intervention. … Evidence was low
or insufficient for other adverse events. … : A systematic
review of adverse event reports in randomized trials. … Acupuncture-related
adverse events: a systematic review of the Chinese
literature.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
December 29, 2020 - administration and study settings (e.g., home, outpatient,
emergency room, and inpatient), lack of data on adverse … Evidence
was insufficient to draw
conclusions about serious adverse
events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - For adults with treatment-resistant depression, do non-pharmacologic interventions differ in
safety, adverse … Adverse effects of interest include but are not limited
to: amnesia, memory loss, headaches, post-operative … : ECT, rTMS, VNS, demonstrated effective psychotherapy
• Outcomes for each question
• Safety
• Adverse … KQ4 focuses on safety issues (adverse effects, adherence) with
each of the interventions. … Remission
Response
KQ2:
Relapse
Recurrence
As measured by validated
instruments
KQ 4: Safety, adverse