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Total Results: 1,401 records

Showing results for "adverse".

341. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - Some of these adverse effects - and the dosing instructions implemented to avoid them - appear to reduce … • Outcomes: - Any reported harms/adverse events (AEs) that can be directly associated with use … , 6) 2º Outcome: Adverse effects of treatment Factors that affect Adherence/persistence with … KQ4 assesses the evidence for adverse effects of treatment. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0.

342. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
     June 01, 2010 - future reproductive outcomes) Question 2 What is the nature and frequency of maternal and child adverse … e.g., infections and sepsis) • Longer term outcomes Question 3 How do the effectiveness, adverse … Question 4 How do the effectiveness, acceptability, adherence, adverse effects, and safety of progestogen … Question 5 How do the effectiveness, adverse effects, and safety of progestogen treatment differ based … Adverse events may occur at any point after the treatment is received, and are affected by patient factors

343. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
     February 22, 2012 - delivery of a cytotoxic dose of ionizing radiation to the tumor volume, while attempting to minimize adverse … It involves numerous treatment sessions, with dose fractionation, and can lead to adverse effects related … , hemoptysis, dermatitis, etc.), non–RT-associated adverse events (e.g., pneumothorax, pleural effusion … Direct evidence of the impact of the various therapies on health outcomes, including adverse effects … Direct evidence of the impact of the various therapies on health outcomes, including adverse effects

344. celiac-disease-protocol-140612 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
     June 12, 2014 - which diagnostic methods were being examined for accuracy, and what is meant by direct and indirect adverse … with IgA deficiency f- Patients previously testing negative for CD Question 4: What are the direct adverse … We provide below an analytic framework to illustrate the population, interventions, outcomes, and adverse … event* OR adverse effect* OR harm* OR enteropathy OR "quality of life" OR villous atrophy OR abdominal … effect* OR adverse event* OR harm* OR bleeding OR perforat* OR danger* OR safe*[tiab] OR safety[tiab

345. Topic 0410 Imaging to Diagnose and Statge SCLC and NSCLC NSD SJ clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0491-140827.pdf
     February 19, 2014 - imaging modalities and biopsies Outcome(s): Morbidity, mortality, hospitalizations, occurrence of adverse … The associated costs and adverse clinical outcomes are of particular concern due to the size of the

346. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - It fails to include certain key information as it did not incorporate adverse event data from the FDA … It was outside the scope of this review to search the FDA’s adverse events database. … have the authors report on adverse event data submitted to the FDA? … a network meta-analysis for other adverse effects. … We grouped the adverse outcomes in consultation with the technical expert panel (Table 3).

347. Surveillance & Identification of Triggers for Updating Systematic Reviews for the EHC Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
     August 01, 2012 - What is the comparative effectiveness of IMRT, 3DCRT, 2DRT, and proton beam therapy regarding adverse … with fewer cases of xerostomia at 6, 12, 24, and 36 months compared to 2DRT. 7 No signal Other Adverse … Events: The incidence of other adverse events i.e. dermatitis 7 and dysphagia 6 favored IMRT treatment … The original CER reported inconsistent results for other adverse events. … Similarly inconsistent results for adverse events were found in the original CER 1 signal (A1)

348. Multiple-Sclerosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
     April 01, 2015 - People with MS commonly switch between the available DMTs, depending on tolerance, presence of adverse … Event At Least 1 Serious Adverse Event Treatment Discontinuation for Adverse Event Comparator … Dropouts from observational studies are more likely to bias reporting toward lack of adverse events … Adverse events and inefficacy or progression of disability were two expected categories. … Current treatment strategies for multiple sclerosis - efficacy versus neurological adverse effects.

349. Disposition of Comments for Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis -- Update of a 2007 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
     March 01, 2012 - We did not use a 0.5 correction factor for the adverse events analysis. … We did not add a 0.5 correction factor for adverse events analysis. … Finally, we do state explicitly that the study assessed fractures as adverse events. … For this review, we relied solely on trial data for all but very rare adverse events. … Peer Reviewer 4 General: Adverse Events The adverse events section is problematic.

350. Atrial-Fibrillation-Ablation Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
     May 16, 2013 - The overall rates of complications/major adverse events were under 7%.9,10,15,18-20,25. … There were 84 studies that reported at least one adverse event associated with RFA. … Most of the studies did not report the time of occurrence of the adverse events. … Major adverse events associated with RFA are relatively uncommon. … of the various adverse events were not always comparable.

351. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update--Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
     January 01, 2018 - Neuroleptic malignant syndrome is a rare but serious adverse effect. … In KQ2, we assessed harms across conditions in terms of adverse effects (AEs) categorized as major … Within each comparison, we begin with findings for major adverse effects (AEs) followed by general … Summary of findings for general adverse effects: Short-term durations of FGAs versus SGAs Outcome N … doses of SGAs (continued) AE = adverse effect; BMI=body mass index; CI = confidence interval; CrI =

352. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
     November 27, 2012 - This is in contrast to Telaprevir’s association with dermatological adverse events, which are unique … Please revise to reflect an accurate assessment of adverse event rates. … We have have made distinctions in our report regarding the adverse events for each drug. … Please revise to reflect an accurate assessment of adverse event rates. … Anemia rates were calculated based on clinician adverse event reports.

353. A Systematic Review of Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
     April 20, 2022 - Reduction of health disparities* (increase in disparities included under Harms) ● Harms o Severe adverse … ● Reduction of health disparities* (increase in disparities included under Harms) ● Maternal harms/adverse … loss of reflexes, reduced urine output, need for calcium infusion)* o Other clinically important adverse … events • Adverse drug interactions Literature Search Strategies to Identify Relevant Studies to … Association of Adverse Pregnancy Outcomes With Hypertension 2 to 7 Years Postpartum.

354. Disposition of Comments_Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-disposition-comments.pdf
     July 31, 2024 - Also, further studies should also focus on WHY some patients experienced adverse effects while others … We agree that assessing risk for adverse effects is an area for future research and note that many … the included studies restricted participants to those with few risk factors for complications or adverse

355. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - Experts Conclusion from SCEPC Conclusion #1 In the catheter aspiration trials, the risks of major adverse … There was a paucity of trials available to evaluate adverse events with any of the embolic protection … conventional PCI 25 trials including 5,534 patients Major adverse cardiac events were significantly … Do Not Know Conclusion #1 In the catheter aspiration trials, the risks of major adverse cardiovascular … There was a paucity of trials available to evaluate adverse events with any of the embolic protection

356. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - In addition to effectiveness, decisionmakers need information on potential adverse risks, and special … Pain, function, pain relief satisfaction and quality of life, harms/adverse events (including withdrawal … predicting risk of opioid misuse, opioid use disorder, or overdose (KQ 1 h) Mitigation strategies Adverse … We will grade SOE for the two most critical health outcomes, pain, function, quality of life, and adverse … treatment patterns of prophylactic and acute migraine medications and incidence of opioid-related adverse

357. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - Several instruments are available to monitor treatment response and adverse effects over time, including … Monitoring also includes assessment of any adverse effects of treatment. … What are the adverse effects associated with being labeled correctly or incorrectly as having ADHD? … In question 1d, we will assess whether the literature suggests whether these adverse effects differ … Questions 2 and 3 will review effectiveness as well as adverse outcomes. III.

358. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain-surveillance-151130.pdf
     July 10, 2015 - Perioperative adverse events after minimally invasive abdominal sacrocolpopexy. … The study comparing goserelin versus progestogen did not report on adverse effects. … Studies did not report on adverse effects. … Studies did not report on adverse effects. … effects (e.g. weight gain, bloatedness-the most common adverse effects).

359. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
     December 07, 2024 - events, serious adverse events • Timing: o No limitation on study duration or length of follow up … Serious Adverse Event Percent 3. Serious Adverse Event Detail 4. … Serious Adverse Events Numerator 5. Serious Adverse Events Denominator 6. … Withdrawal Due to Adverse Events Percent 7. Withdrawal Due to Adverse Events Detail 8. … Withdrawal Due to Adverse Events Numerator 9. Withdrawal Due to Adverse Events Denominator 10.

360. Disposition of Comments for Technical Brief 24 Resident Safety Practices (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
     May 27, 2016 - We have revised the abstract to note the trade-off between QoL and some types of adverse events. … Peer reviewer #5 Background The list of adverse events is organized poorly. … The focus should be on adverse events. … I wanted a list of adverse events they would discuss and why these were chosen. … How this relates to harm and adverse events is not articulated well.