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Showing results for "adverse".

  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - risk of suicide, each of which compromises the health of both the woman and her fetus.5,6 Several adverse … Framework The analytic framework below illustrates the population, interventions, outcomes, and adverse … reports • Withdrawals from study and discontinuation of treatment due to adverse events Source: … events associated with discontinuation of treatment • Serious adverse events reported Fetus, Infant … Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - • Adverse events will be evaluated from studies of the drugs used for osteoarthritis, rheumatoid … Also, adverse events may occur at any point after the treatment is received. IV. Methods A. … We assumed that the adverse events occurred independently and that the logarithm of the rate ratios … , we estimated the net effects on all three serious adverse events using Monte Carlo simulation. … We also pooled clinical success rates and withdrawal due to adverse events from head- to-head trials
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-e1-4.xlsx
    January 01, 2025 - Adverse Events Table E-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … With Any Adverse Event Intervention D, N of Any Adverse Event (Numerator) Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
    September 03, 2019 - events is critically important The specific adverse events that were selected for this report, and … The specific adverse events that were selected for this report, and were graded (implying a higher … adverse events but those reported to be severe by the individual trials. … an adverse event in the trial, regardless of what that adverse event was. … The outcomes are defined (including “any adverse event” in the methods chapter).
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - Example 1: High false-positive rates in screening tests (e.g., mammography) make adverse emotional effects … The key questions in the review focused on the reduction in adverse pregnancy outcomes and the adverse … Clinical Management Effects Included in the systematic review: Does screening reduce adverse pregnancy … Specifically, they included the adverse effects of therapies and the benefits of reducing adverse pregnancy … The test itself may result in adverse effects that must be treated and, therefore. generate a cost.
  6. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - Example 1: High false-positive rates in screening tests (e.g., mammography) make adverse emotional effects … The key questions in the review focused on the reduction in adverse pregnancy outcomes and the adverse … Clinical Management Effects Included in the systematic review: Does screening reduce adverse pregnancy … Specifically, they included the adverse effects of therapies and the benefits of reducing adverse pregnancy … The test itself may result in adverse effects that must be treated and, therefore. generate a cost.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
    January 01, 2007 - What adverse events and complications have been associated with aggressive medical therapy or renal … Adverse events (including 30 day mortality) No new data on adverse event rates among comparative studies … Adverse events (including 30 day mortality) A total of 22 studies reported adverse events immediately … , though serious long-term adverse events were rare. … Reported adverse events from antihypertensives were relatively minor and transient.
  8. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - However, experts noted that patients would likely be concerned about potential adverse events. … The researchers also reported that the most common adverse events “included headache (35%), nausea … The most commonly reported (≥10%) adverse reactions in patients treated…across all clinical studies … Of subjects receiving the recommended dose of 0.05 mg/kg/day, 88.3% (n=68/77) experienced an adverse … Many of these adverse reactions were reported in association with the underlying disease and/or use
  9. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - However, experts noted that patients would likely be concerned about potential adverse events. … The researchers also reported that the most common adverse events “included headache (35%), nausea … The most commonly reported (≥10%) adverse reactions in patients treated…across all clinical studies … Of subjects receiving the recommended dose of 0.05 mg/kg/day, 88.3% (n=68/77) experienced an adverse … Many of these adverse reactions were reported in association with the underlying disease and/or use
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    May 29, 2025 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and Adverse … See above Addendum Appendix Abbreviations Abbreviations for Addendum Appendix Acronym Term AE adverse
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
    August 01, 2022 - No significant adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported. … No serious adverse events were observed. … No serious adverse events, death, and withdrawal due to adverse events were reported. … No patients reported adverse events.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
    November 24, 2014 - Although most adverse effects are minor, such as constipation, diarrhea, and dizziness, they frequently … events (safety and tolerability): overall adverse events, withdrawals because of adverse events, serious … adverse events, specific adverse events (including hyponatremia, seizures, suicidality, hepatotoxicity … , weight gain, gastrointestinal symptoms, sexual side effects), withdrawals because of specific adverse … events, results, and adverse events reported.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
    November 30, 2011 - dosages and durations of treatment according to various factors. 10 A common (50 to 60 percent) adverse … In addition, psychiatric, gastrointestinal, dermatological, and hematologic adverse effects underlie … , hepatic cirrhosis, hepatocellular carcinoma, and liver transplants  Transmission of HCV Adverse … effects of intervention(s)  Harms from antiviral treatment, including withdrawals due to adverse … events, serious adverse events such as severe neutropenia, psychological adverse events, flu-like
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
    November 01, 2023 - Collection of adverse events data was notably inconsistent across studies. … In particular, although some studies reported all adverse events, others only reported them in the situation … Trials of topiramate reported increased risks of many adverse events, including paresthesias, taste … For most serious harms, there was insufficient data to determine comparative rates of adverse events
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - Given the availability of alternative treatments and concern about adverse clinical outcomes in clopidogrel … events and liver toxicity) o Adverse effects of testing per se (including test-related anxiety and … adverse events secondary to venipuncture) … effects of test-directed treatment KQ 1c, 2c, 3b KQ4 KQ4 Adverse effects of genetic testing … Adverse effects of phenotypic testing KQ4 KQ4 Patients with cardiovascular, cerebrovascular
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
    June 01, 2017 - Secondary Adverse events, otoscopic exams, audiometry, and tympanometry Microbiological response … In general, there were few serious adverse events and many other adverse events. … showed more adverse events in the intervention group. … events, including serious adverse events (not defined), other adverse events (not defined), and acute … Question 3: What adverse events, surgical complications, and sequelae are associated with inserting
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
    September 22, 2014 - improved appropriate antibiotic use is expected to have other benefits, particularly a reduction in adverse … Key Question 5: What are the comparative non-clinical adverse effects of strategies for improving the … Key Question 2 • Mortality • Antibiotic resistance • Medical complications • Adverse drug effects … Adverse!drug! effects)! KQ3:# ! Time!to!return!to!work/! school! ! Clinic/ED!visits,!admission! … Adverse!effects! of!the!strategy!
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - This is particularly a problem for rare adverse events. … By including observational studies, we capture a better assessment of adverse effects. … Peer Reviewer # 3 Methods Adverse event reporting. … For withdrawals, we reported overall withdrawals and withdrawals due to adverse events. … The adverse effects were minor for the most part.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
    August 01, 2016 - Adverse events: • What adverse effects are related to n-3 FA intake (in studies of CVD outcomes and … study arms, and no serious or severe adverse event was attributed to n-3 FA. … Six of the marine oil trials explicit stated that most or all adverse events were mild. … • No serious or severe adverse events were related to n-3 FA intake (supplementation). … differences in serious or nonserious adverse events between marine oil and placebo.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - We would like to suggest that the researchers consider consulting other data sources such as adverse … Conceivably, information from adverse event databases would support the clinical impression that the … The purpose of this section is to describe the potential adverse events that may be encountered in … Aside from the risk itself, the emergence of a new adverse event from an outside meta-analysis raises … adverse event rates but no more benefit than a single drug.

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