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Total Results: 1,401 records

Showing results for "adverse".

281. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
     March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … Outcomes included adverse effects, intermediate outcomes, and final health outcomes. … KQ 4: In patients with cystic fibrosis, what is the frequency of nonmalignant serious adverse effects … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of

282. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - It is hoped that the studies available to inform these outcomes include information on other adverse … As noted in the previous report, transfusion-related adverse events are uncommon. … , rEPO antibodies, and transfusion adverse events. … NOTE: No quality assessment of observational (adverse effects) studies will be conducted. E. … effect*” OR “adverse drug reaction*” OR “side effect*” OR “toxic effect*” OR “adverse event*” OR “complication

283. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
     April 17, 2012 - Research indicates that individuals can reduce their risk of obesity-related adverse health conditions … However, concerns over potential adverse events associated with antiobesity pharmacotherapies have … Another expert with a research perspective expressed concern about adverse gastrointestinal events … The potential was tempered by experts’ significant concerns about adverse events reported thus far. … discontinuation rate, which they believe to be significant adverse factors.

284. Surveillance Report: CER 30: Comparative Effectiveness of Pain Management for Hip Fracture (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
     July 08, 2015 - effects – adverse effects related to the pain management intervention, mental status, health related … There were no significant differences between groups for the following adverse effects: •! … The reported adverse effects were from one to two studies, and did not demonstrate any significant … There were no significant differences between groups for the following adverse effects: •! … The reported adverse effects were from one to two studies, and did not demonstrate any significant

285. Colorectal-Surgery-Preparation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
     April 01, 2014 - Individuals who may be at greater risk of adverse effects of OMBP are the elderly (≥65 years of age … For Key Question 2 we considered the following prespecified adverse events (harms): nausea; vomiting … Almost universally, the rates of reported adverse events were below 4 percent. … No studies reported adverse events by any of the prespecified subgroups of interest. … Hartmann's reversal is associated with high postoperative adverse events.

286. Cer-250-Cannabis-2024-Surv-Rep-Update-Tables-E1-4 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-e1-4.xlsx
     January 01, 2024 - Adverse Events Table E-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … With Any Adverse Event Intervention D, N of Any Adverse Event (Numerator) Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention

287. Treatment Resistant Depression Surveillance FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
     April 01, 2016 - For reviewing adverse events (KQ 4), per our standard approach, we include observational studies. … (SOE: Insufficient) Specific adverse events. … We looked at both withdrawals that investigators attributed to adverse events and overall numbers … (SOE: Insufficient) Specific adverse events. … A single study with a small sample size indicated no difference in withdrawals due to adverse

288. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - • Adverse effects of the interventions were inadequately reported in many studies. … All studies focused on benefits of physical activity, with inadequate reporting of adverse events in … activities, and intensity of physical activity; incomplete data analysis; inadequate reporting of adverse

289. CER 226: Evidence summary_Labor Dystocia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
     May 01, 2020 - Partogram use: Evidence summary for major outcomes and adverse events Category Outcome Study Design … Low (non-U.S. setting, 1 study) Adverse Events Maternal Outcomes – Hemorrhage 3 RCTs24,25,29 … Moderate (Indirect, consistent) Existing SR was consistent with RCT findings Adverse Events … High Adverse Events Maternal Outcomes – Infection 3 RCTs37 (1,933) 2 SRs44-46 (3,475 patients … Low (Indirect, 1 study) Adverse Events Maternal Outcomes – Trauma to the Pelvic Floor 1 RCT76

290. Kidney-Disease-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
     October 01, 2012 - are available - For KQ5 (benefits of treatment) and KQ6 (harms of treatment) there were several adverse … Adverse event signals should be followed up 8 Conclusions From CER Executive Summary RAND … events data from different studies, adverse events reported generally were consistent with known … Relation between kidney function, proteinuria, and adverse outcomes. … Adverse effects were more common in bardoxolone group including mild, dose-related muscle spasms,

291. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
     December 01, 2011 - larger infarcts, significant left ventricular systolic dysfunction, and an increased risk of a major adverse … In patients with ACS who are undergoing PCI of native vessels, how do the rate and type of adverse events … The outcomes are separated into adverse events, intermediate outcomes, and final health outcomes. … The adverse events of note include coronary dissection, perforation, and prolonged procedure time. … Note: ACS = acute coronary syndrome; KQ = Key Question; MACE = major adverse cardiovascular event; MBG

292. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
     December 06, 2010 - Many questions remain about the risks of these agents across a spectrum of adverse events—from relatively … 3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence, or adverse … Morbidity, mortality, and other serious adverse events ii. Tolerability iii. Adherence iv. … Other adverse effects • Timing: Minimum of 3 months of follow-up • Settings: Primary care … Also, adverse events may occur at any point after the treatment is received. IV. Methods A.

293. Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
     January 01, 2020 - Case-control studies compare people who have a disease or adverse event (“cases”) with people who do … Broad categories such as “injection-related adverse events,” “systemic adverse events,” “one or more … adverse events,” or “serious adverse events” were reported rather than specific AEs. … Adverse Effects of Vaccines: Evidence and Causality. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0. May 28, 2009. 19.

294. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
     March 09, 2010 - • Adverse events: These are specific to the interventions being examined (see Table 2). … In addition, adverse events may occur at any point after the treatment is received. … • Case control studies are acceptable to assess for adverse events of DMARD treatment (KQ3, KQ4) … We will review the quarterly data files from the United States Food and Drug Administration Adverse … Event Reporting System (AERS) from July 2008 to June 2009 for adverse events related to JIA treatment

295. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
     January 01, 2010 - for clinical outcomes among patients receiving clopidogrel treatment for the prevention of major adverse … guiding treatment choice for patients who require antiplatelet therapy for the prevention of major adverse

296. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
     October 08, 2014 - (elective) as a result of an adverse … dose until eliminated; may be replaced with other immunosuppressant Planned de novo or result of adverse … Populations at increased risk for graft rejection or other adverse outcomes will be included for all … The adverse events and harms reported by any study included to address any of the questions will be … used to assess harms and adverse events related to therapeutic monitoring of CNIs and CNI treatment

297. Mental-Illness-Heart Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
     April 01, 2013 - Adverse effects of psychotropic drugs (notably second-generation antipsychotics) also may contribute … effects, and adverse effects (KQs 1–4). … For adverse effects, we report significant worsening of psychiatric status and discontinuations due … to adverse effects. … For adverse effects, we considered discontinuation due to adverse effects and worsening of psychiatric

298. Hepatitis-C-Treatment-Adherence Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
     September 22, 2011 - treatment is challenging because of the lengthy duration, complex treatment regimen, and frequent adverse … Nonadherence to HCV treatment may be associated with a lack of management of adverse events,5,10 higher … Adverse Event Management Interventions Versus Usual Care/Placebo Key Points • There were no studies … of the effects of adverse event management interventions on health outcomes besides QOL. … Although neither study found adverse events associated with the use of epoetin or citalopram, both

299. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
     November 01, 2010 - 700,000 individuals will have end-stage renal disease (ESRD) by 2015.6 Association of CKD with Adverse … Clinical Outcomes Numerous adverse health outcomes have been associated with the presence of CKD … The majority of evidence associating CKD with adverse outcomes is derived from cohort or observational … , there appears to be a graded relationship between the severity of proteinuria or albuminuria and adverse … There are a number of possible explanations for the observed association of CKD with adverse health

300. Glaucoma-Treatment-Appendices-11-5-10-2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment-appendices-11-5-10-2.pdf
     October 27, 2009 - TREATMENTS 1 Generic Name Brand Name Adverse Reaction Ocular Cardiovascular Central Nervous … Renal failure, polyuria APPENDIX A3 ADVERSE … allergic skin reaction APPENDIX A3 ADVERSE … insomnia • pharyngitis APPENDIX A3 ADVERSE … DEFINITIONS AND ABBREVIATIONS ABBREVIATIONS AE Adverse events AHRQ Agency for Health Related