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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - • Although associations may exist between psychotropic medications and adverse
events, causality … For child adverse outcomes, we found an association
between benzodiazepine and neonatal intensive care … evidence
available is consistent with some benefit; and (4) some studies suggested some increased
adverse … underlying mental health disorder as the cause of the
association, the causal link between the exposure and adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
May 29, 2025 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
May 29, 2025 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - Eligibility Criteria Interventions Sample Characteristics Screened
Eligible
Randomized
Analyzed Results Adverse … Events and Withdrawals Due to Adverse Events Sponsor Quality
Hruschak, 2021 RCT
Duration: 6 weeks University … Abbreviations: AE = adverse event; BMI = body mass index; CI = confidence interval; COWS = Clinical Opiate … B
Major adverse cardiovascular events: 52 vs. 72
Incidence rate per 10,000 person months (95% CI): 30.12 … event
B: Controls: (n=2,311), patients without an opioid-related adverse event, 1:1 matching based on
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - Moreover, study withdrawal is not a specific
measure of adverse events. … Our focus was on response
and adverse effects associated with active treatment. … We studied adverse effects when reported. … We described specific adverse effects in the
text. … We described specific adverse effects including
deaths in the text.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - Few adverse
drug withdrawal events resulted from deprescribing interventions. … drug events,
adverse drug withdrawal events, mortality)
Implementation measures
(e.g., barriers … Importantly, deprescribing was associated with few adverse drug withdrawal events. … Adverse
drug events in ambulatory care. … Reducing Adverse Drug Events in Older
Adults.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Table 2 provides a summary of primary
outcomes and adverse effects. … Harms
Each study measured adverse effects differently, reporting either incidence of specific
adverse … Harms
Adverse effects were measured differently in each RCT. … Harms
Each study measured adverse effects differently, reporting either the incidence of serious
adverse … Adverse effects were
rare in all treatment arms.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - We will report adverse events as they are reported by the authors of the study. … Examples of
adverse events that we have identified a priori are listed in KQ5 above. … with an adverse
event. … Hyperglycemia and adverse pregnancy outcome (HAPO) study Cooperative Research
Group. … Hyperglycemia and adverse pregnancy outcomes. N Engl J Med
2008;358(19):1991–2002.
19.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
January 07, 2014 - Additionally, the nominator is interested in the adverse effects of pharmacotherapy
treatment options … Changes in disease severity scores / pressure-flow-volume
measurements for adult males with LUTS/BPH; adverse … What are the adverse effects of pharmacotherapy treatment options for LUTS
secondary to BPH, including
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
January 01, 2025 - care or a different
institution) that reported patient clinical outcomes, such as medical errors, adverse … Preventable
adverse events decreased from 3.3 per 100 admissions to 1.5 per 100 admissions
(p=0.04) … Preventable adverse events decreased from 4.7
per 100 admissions to 3.3 per 100 admissions (p<0.001) … events per
1,000 hospital days:
Intervention: 60.4
Control: 60.4
Total adverse events per
1,000 … Study: new approach to handoffs slashes errors,
preventable adverse events; other medical
centers
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - o Treatment discontinuation due to adverse effects. … Time course of adverse events most commonly
associated with topiramate for migraine prevention. … Are migraineurs at increased risk of adverse drug
responses? … A systematic review of adverse events in placebo
groups of anti-migraine clinical trials. … Adverse effects of medications commonly used in the treatment of
migraine.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - No serious adverse events, death,
or withdrawal due to adverse events were reported.
8
A subgroup … No serious adverse events or withdrawal due to adverse
events were reported. … No adverse events
were reported in either groups. … No
serious adverse events, death, and withdrawal due to
adverse events were reported. … No
significant adverse events were reported.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported.
12
The other two new … , including any adverse event, nausea, dizziness, and
somnolence.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-tables-F1-4.xlsx
January 01, 2022 - Adverse Events
Table F-4. … Any Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for … Any Adverse Event (Denominator) Intervention B, % With Any Adverse Event Intervention C, N of Any Adverse … Adverse Event (Denominator) Intervention D, % With Any Adverse Event Intervention A, N of Serious Adverse … Cannabis RCTs adverse events
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - challenge and focus of current research is improving the natural history
of disease while minimizing adverse … to: (1)
induction of Crohn’s disease remission; (2) maintenance of Crohn’s disease remission; (3)
adverse … to: (1) induction of Crohn’s disease remission;
(2) maintenance of Crohn’s disease remission; (3) adverse … and
children with moderate-to-severe Crohn’s disease in terms of minimizing short- and long-term
adverse … and other cancers
• Infections
• Infusion and injection-site reactions
• Bone fractures
• Other adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - The overall rate of
serious adverse events was higher with
rofecoxib than with naproxen. … The overall rate of serious adverse
events with celecoxib was similar to the rate
with ibuprofen and … • Lumiracoxib vs. nonselective NSAID
• Results from one large trial (TARGET) found
fewer adverse GI … to
adverse events were similar … events and withdrawals
due to adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
December 20, 2012 - TEP #5 Executive Summary Throughout the review, the authors use the term “adverse
effects”—it may be … more appropriate and consistent with the
HCV literature to use another term such as “adverse side … effects” “adverse events”, or “side effects.” … We
have replaced adverse effects with
“adverse events” throughout the
document. … If studies of adverse
effect management are included then this list is far from
complete.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - Adverse effects were not consistently reported or specified
in the methods of the studies. … In general, adverse effects were transient
and mild.
9
Table C. … Adverse effects were not consistently reported or specified
in the methods of the studies. … In general, adverse effects were
not mentioned in these reports.
10
Table D. … Our review also showed that adverse
effects were generally poorly evaluated and reported.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - I
found that the adverse reaction reporting system was a bit confusing,
reporting by systems as well … Peer Reviewer #3 Results (Pg 52) One reason for the low adverse events rate in the etanercept studies … are the active run-in periods that excluded children who had adverse
events. … We have added the following
sentence as a Key Point: “Adverse event
rates may be underestimated by … The adverse events data from
that study are included in the Appendix.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/mhs-IV-epc-grand-rounds-slides.pptx
January 01, 2023 - A PSP is an intervention, it’s a type of process or structure whose application reduces the risk of adverse … of report cards and outcome measurements to improve safety of surgical care
Deprescribing
Reducing adverse … of opioids…” through “maximizing clinical benefits for patients and the wider society and minimizing adverse … mortality and arrest incidence in adults (low SOE); unclear in children (insufficient SOE)
Serious adverse … ) caregivers as it may:
Improve clinical outcomes for patients, reduce preventable utilization and adverse