-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
April 01, 2012 - effects, and discontinuation due to adverse effects. … Fesoterodine resulted
in higher rates of adverse effects and discontinuation of
treatment due to adverse … Risk of adverse effects was greater
with trospium than with placebo. … Adverse effects were
common with all drugs and varied between the drugs. … Treatment
discontinuation due to adverse effects of drugs is
common.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - Serious transfusion-related
adverse events are uncommon. … For
example, in the United States, adverse
events due to errors in transfusion are
Comparative Effectiveness … A review of these various
trials may help maximize benefit, optimize drug usage,
and minimize adverse … For other adverse events, reporting is incomplete,
representing less than one-third of patients. … More evidence is needed to delineate the effects
on survival, tumor progression, and risk of adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - When lesinurad was combined with xanthine oxidase inhibitors,
commonly reported adverse events were … However, the experts warned that lesinurad uptake could be
limited by concern about adverse events, … adverse events, than patients given placebo. … Adverse events/nonfatal serious adverse events rates were
78.1%/8.6% and 82.4%/12.9% in patients who … ; treatment-emergent adverse event rates were not reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - NEBA is used to provide clinical
support but does not replace the clinical evaluation.14
Adverse … Adverse Effects of Treatment: Adverse effects associated with pharmacologic treatment can
include changes … Adverse effects of nonpharmacologic treatment depend on the specific intervention. … These adverse effects are not likely to expand beyond those expected for pharmacologic therapy. … § Adverse effects of treatment include changes in appetite, growth suppression,
weight decrease,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - Similar to RA trials,
many questions remain about the risks of these agents
across a spectrum of adverse … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or adverse … events,
and specific adverse events if data were available (e.g.,
injection-site reactions, infections … Overall adverse event
profiles appeared to be similar for biologic
DMARDs and placebo. … Information generally was insufficient for the comparative
harms, tolerability, adverse events, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - adverse events according to drug class? … Harms and Adverse Events ...................................................................... … Harms and Adverse Events
a. … adverse events, according to drug class? … events, and serious adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - of these medications is supported
by several systematic reviews.8-12 Due to the potential serious adverse … The proposed advantages over anticholinergics include potentially lower rates of
adverse effects and … We will synthesize available data regarding
efficacy, comparative effectiveness and adverse effects … Also, adverse events may occur at any point after the treatment is initiated.
IV. Methods
A. … Update on AUA guideline on the review of efficacy and adverse effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - But it is well recognized that regimens vary in their potential for long-term
adverse effects, so this … Mitigation of long-term adverse effects by changes in regimen, including reduced-intensity
approaches … Mitigation of long-term adverse effects by changes in regimen, including reduced-
intensity approaches … But, it is well recognized that regimens vary in their
potential for long-term adverse effects. … Role of novel therapies for HSCT in altering short-term adverse effects and the long-term
effects of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
June 01, 2013 - had no adverse events data. … Thus, strength of evidence for long-term adverse
events is rated insufficient. … Data reported on adverse events also have several
limitations. … event category; thus, the rate estimate for most
adverse events is imprecise. … As such, the rates of adverse
events may be biased and lower than actual.
-
effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
January 01, 2007 - Developing Indicators of Inpatient Adverse Drug
Events Through Non-Linear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the
Early Detection of Adverse Events. … Evaluation and Overview
of the National Electronic Injury Surveillance System- Cooperative Adverse … A Simulation-Based Evaluation of
Methods to Estimate the Impact of an Adverse Event on Hospital Length
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - , bone density, and cosmetic adverse effects? … Based on the comments received
and input from the Technical Expert Panel, the adverse events listed … effects
• Cosmetic adverse events
• Incidence of adverse events
• Incidence of individual adverse … events
• Incidence of adverse events resulting in therapy withdrawal
• Incidence of adverse events … not resulting in therapy withdrawal
• Skin rash
• Neurological adverse events
• Suicidal ideation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - Treatment
may lead to intermediate outcomes, such as changes in
level of depression symptoms, or adverse … reports, adverse events
associated with discontinuation of treatment, and
serious adverse events … • Withdrawals from study and discontinuation of
treatment due to adverse events
• All-cause mortality … events,
discontinuation due to adverse events, and weight
gain. … Maternal antidepressant
use and adverse outcomes: a cohort study of 228,876
pregnancies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
October 12, 2015 - adverse outcomes, and in some cases preferences for process as well as outcome. … Short-term adverse effects of treatments
!! OHSS
6! … Short-term adverse effects of treatments
!! OHSS
!! Surgical complications
!! … Adverse!effects!of!treatments!(e.g.,!for!PCOS!patients,!
gastrointestinal![GI]!symptoms!for! … adverse!effects!of!treatments!
!! OHSS!
!! Surgical!complications!
!! Adverse!effects!of!
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-disposition-comments.pdf
September 18, 2024 - quality of life, as well as our secondary outcomes such as pain intensity, medication usage,
and adverse … Several reviewers pointed out that adverse events (AE) are not a major concern with
behavioral treatments … noted that we discussed overall dropouts in the AE section, but such dropouts
may not actually be adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - CKD, the kidneys are damaged and/
or cannot filter blood normally.1 CKD
increases the risk for many adverse … • Few trials reported adverse events. … • Although limitations in reporting impeded the
quantitative synthesis of withdrawal and adverse … positive tests (for progression); medication adverse
effects; increased medical visits; increased … CKD Treatment Harms
Knowledge Gaps
Withdrawals and adverse events were reported in few
RCTs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
October 01, 2010 - of the various adverse events were not always
comparable." … Limitations of evaluation of adverse events have been added to
Discussion section. … Discussion Adverse effects: “There is a moderate level of evidence to show that
adverse events associated … These long-term
adverse events need to be explored in future studies. … types of adverse events were
different between groups, as would be expected.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - single classes on venous thromboembolism outcomes, treatment
adherence, major bleeding, and other adverse … postoperative) on venous thromboembolism outcomes, treatment
adherence, major bleeding, and other adverse … KQ 5 also
§ Symptomatic DVT
§ Proximal DVT
o Adherence (compliance) with treatment
• Adverse … events due to mechanical devices (as reported by authors)
o Adverse events due to IVC filter (as … reported by authors)
o Other clinically significant adverse events reported by studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - of individuals have insufficient prehospital pain relief.3 Reasons for this have included
fear of adverse … of their abuse and the
resulting epidemic in the United States.9,10 When combined with concerns of adverse … event
(as in any subject that experienced an adverse event during the study
period)
• KQ2c:
o … Predictors of pain relief and adverse events in
patients receiving opioids in a prehospital setting. … event (as in any subject
that experienced an
adverse event during
the study period).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
October 01, 2006 - Comparison of
adverse events and complications across the various
interventions is difficult. … Thirty-seven of these studies reported on
adverse events. … Adverse events (including 30-day mortality, Table B)
Adverse events were reported in 37 studies, including … Other adverse events reported
included hemorrhage and hematomas, and renal artery
occlusion. … Adverse events N/A • The evidence does not support meaningful conclusions about
relative adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-table-e5.xlsx
January 01, 2025 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … C
Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse