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Showing results for "adverse".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
    March 01, 2012 - The update search identified new data on effectiveness and adverse effects. … were included in the adverse event analysis … included information on the relationship between the adverse event and the drug. … of all adverse events that were reported for any of the drugs. … • Adverse effects—and concerns about adverse effects— appear to be important predictors of adherence
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
    June 01, 2013 - Adverse Effects With Off-Label Pharmacologic Agents: Antiepileptic Drugs Topiramate. … Rates of adverse effects did not differ among 50, 100, and 200 mg/day of topiramate. … , and 17 percent discontinued treatment due to bothersome adverse effects. … Evaluation and registration of adverse events in clinical drug trials in migraine. … Adverse drug reactions and off-label drug use in paediatric outpatients.
  3. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
    May 01, 2010 - What is the comparative effectiveness of IMRT, 3DCRT, 2DRT, and proton beam therapy regarding adverse … evidence is insufficient to draw conclusions about the comparative effects of IMRT and 3DCRT for other adverse … evidence is insufficient to draw conclusions about the comparative effects of IMRT and 2DRT for other adverse … As a result, the patient may be at risk of greater adverse effects from an inadvertently high dose to … Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
    July 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments had few minor adverse effects. … Overview of Clinical Research Evidence (Continued) Table 2: Adverse Effects Associated With Interventions … Longer term information on benefits and adverse effects would better inform clinical decisions for … Substantial and life- altering adverse events sometimes occur after surgery for fecal incontinence,
  5. S81 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
    October 01, 2007 - ORIGINAL ARTICLE Developing Indicators of Inpatient Adverse Drug Events Through Nonlinear Analysis Using … : Because of uniform availability, hospital administra- tive data are appealing for surveillance of adverse … Up to 5 adverse events were evaluated for each admission. … These fields included adverse event codes. … High rates of adverse drug events in a highly computerized hospital.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
    October 01, 2022 - However, treating seizures may have adverse effects that could also contribute to delayed development … We concluded that for three medications (levetiracetam, topiramate, and lamotrigine) adverse effects … For topiramate, we found consistent evidence of dose-response effects for two non-severe adverse effects … For dietary treatments, evidence on adverse effects was insufficient to permit conclusions.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
    January 01, 2023 - There may be no increase in risk of serious adverse events (strength of evidence [SOE]: low) or withdrawal … due to adverse events. … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive deficits) and outcomes … Other prioritized adverse events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
    May 01, 2023 - that evaluated different drugs), length of postpartum hospital stay (reported in only one study), and adverse … studies that addressed quality of life, psychosocial distress, reduction in health disparities, or adverse … ambulation), maternal-neonatal bonding, psychosocial distress, reduction in health disparities, or adverse … Further evidence is needed to determine whether HBPM can reduce the occurrence of adverse clinical outcomes … ✓ Lower dose MgSO4 regimen lowers the risk of magnesium toxicity Other clinically important adverse
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
    January 01, 2023 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07) Serious adverse events: none in any group Withdrawals due to adverse events … C Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04) Withdrawals due to adverse
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
    January 01, 2022 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07) Serious adverse events: none in any group Withdrawals due to adverse events … C Any adverse event: 26.1% (91/348) vs. 14.9% (56/377); adjusted OR 1.00 (95% CI 0.64 to 1.58) NR No … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04) Withdrawals due to adverse
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
    March 01, 2024 - • The identified diagnostic studies did not assess the adverse effects of being labeled correctly … significant differences between stimulant and non-stimulant medications for most effectiveness outcomes and adverse … Furthermore, the identified studies did not assess the adverse effects of being labeled correctly or … effectiveness outcomes, such as ADHD symptoms (SMD 0.23; CI -0.03, 0.49; 7 studies, n=1611; low SoE) and adverse … Across studies, medication therapy evaluations reported more adverse events than non-medication interventions
  12. effectivehealthcare.ahrq.gov/products/depression-harms/research-protocol
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief1-care-coordination.pdf
    April 01, 2021 - disruptions in pain management, which could result in worsened quality of life, function, and other adverse … persons with pain are often discharged on opioids; such patients may be at risk for opioid-related adverse … transitional care interventions represent a potential opportunity to optimize management and reduce adverse … entitled to Medicare with pain represent a potential opportunity to optimize management and reduce adverse … 1 Outcomes Pain, function, quality of life, readmission, pain management (including opioid use), adverse
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
    April 01, 2021 - disruptions in pain management, which could result in worsened quality of life, function, and other adverse … persons with pain are often discharged on opioids; such patients may be at risk for opioid-related adverse … transitional care interventions represent a potential opportunity to optimize management and reduce adverse … entitled to Medicare with pain represent a potential opportunity to optimize management and reduce adverse … 1 Outcomes Pain, function, quality of life, readmission, pain management (including opioid use), adverse
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
    January 01, 2011 - Effect Methods Group57 and other experts.58,59 Adverse Effects/Harms A search for adverse effects … Systematic reviews of adverse effects: framework for a structured approach. … Including adverse effects. In: Higgins JP, Green S, eds. … A survey of the methods used in systematic reviews of adverse effects. … Golder 2006 Adverse Effects search approach MEDLINE EMBASE specified adverse effects Drug terms AND
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
    January 01, 2025 - that have potential analgesic effects as well as the potential for addiction, misuse, and serious adverse … There may be no increase in risk of serious adverse events (SOE: low) or withdrawal due to adverse events … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive deficits) and outcomes … Other prioritized adverse events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
    June 01, 2022 - No serious adverse events were observed. … There were no treatment- related adverse events. … and withdrawals due to adverse events compared with placebo. … No serious adverse events were observed. … No treatment related adverse events were reported.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
    November 26, 2024 - cognitive impairment, and substance use disorders.10 This project will investigate the epidemiology and adverse … term")) OR (title: ("long term")) OR (title: ("longer term")) OR (title: (outcomes)) OR (title: ("adverse … event")) OR (title: ("adverse events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … (abstract: ("long term")) OR (abstract: ("longer term")) OR (abstract: (outcomes)) OR (abstract: ("adverse … event")) OR (abstract: ("adverse events")) OR (abstract: (consequence)) OR (abstract: (consequences
  19. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
    November 01, 2009 - Four reviewers identified studies of any design describing clinical outcomes or adverse events with 10 … of four reviewers extracted study, patient, and treatment characteristics; clinical outcomes; and adverse … Seventy-five percent of studies (188) reported the adverse events. … Not all studies adopted established scales to evaluate adverse events. … However, it was not clear whether the reported adverse events were exclusively attributable to charged
  20. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
    February 01, 2008 - All treatment options result in adverse effects (primarily urinary, bowel, and sexual), although the … Even if differences in therapeutic effectiveness exist, differences in adverse effects, convenience, … Data from nonrandomized trials are inadequate to reliably assess comparative effectiveness and adverseAdverse effects were reported, but definitions and severity varied widely. … effects of Medium • Adverse event definitions and severity varied widely.

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