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effectivehealthcare.ahrq.gov/products/tinnitus/research
August 23, 2013 - Data on adverse effects were generally poorly collected and reported. … The SOE for the adverse effect of sedation in pharmacological studies was judged insufficient. … For KQ2, future research should concentrate on improving collection of adverse effects, calculating sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
September 18, 2012 - Our work will expand the consensus
report Adverse Effects of Vaccines: Evidence and Causality, which … (CTCAE) classification system, and serious
adverse events (SAE) will be defined and coded. … The absolute risk of serious adverse events (SAEs) will
also be computed. … event
CTCAE = Common Terminology Criteria for Adverse Events
Hib = Haemophilus influenzae type b … Adverse events of interest, included in electronic search terms
Adverse event Vaccine type
Acute
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effectivehealthcare.ahrq.gov/products/coronary-stents-antiplatelet-therapy/abstract
January 31, 2011 - Adverse events after stopping clopidogrel in post-acute coronary syndrome patients: insights from a large … Delays in filling clopidogrel prescription after hospital discharge and adverse outcomes after drug-eluting
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
June 15, 2011 - Does the risk of adverse effects differ according to patient baseline diet and fluid intake?
c. … Does the risk of adverse effects differ according to characteristics of stone history? … Does the risk of adverse effects differ according to patient baseline diet and fluid intake?
c. … Does the risk of adverse effects differ according to characteristics of stone history? … adverse treatment effects may manifest in less than 1 year.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - Adverse events associated with medical,
surgical, and endoscopic treatments
The quality of reporting … of adverse events and
complications was inconsistent across studies. … Higher adverse event rates were described for PPIs
than for H2RAs or placebo. … PPIs (1 RCT): no direct
comparative adverse event data reported in this study; in surgical
group, 3.7% … There are no direct comparative adverse event data for endoscopic
vs. laparoscopic procedures.
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effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
February 01, 2016 - We also evaluated adverse effects,
including serious adverse events (e.g., anaphylaxis
with medications … placebo: Adverse events,
serious adverse events
Moderate Antidepressants were associated with higher … in
risk of adverse events. … Yoga: Adverse events Low Reporting of harms was suboptimal, but adverse events, when
reported, were … No serious adverse events were reported, and most adverse events
were related to muscle soreness or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
January 01, 2016 - What are the comparative nonclinical
adverse effects of strategies for improving the
appropriate use … Adverse drug effects, including Clostridium difficile infections.
Mortality. … Although
no study examined all possible adverse consequences, we
considered evidence suggesting no … , some showing adverse impact). … of benefit and adverse
consequences.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
July 01, 2013 - Adverse effects of nasal antihistamines may
include a bitter aftertaste. … Other
local adverse effects may include nosebleeds, stinging,
burning, and dryness. … How do adverse effects vary with intermittent or
continuous use?
Key Question 3. … How do effectiveness and adverse effects vary with
intermittent or continuous use? … Three or more trials reporting the adverse
event were required for pooling.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - It also found strong evidence
that atypical antipsychotics can increase chances of adverse events such … between the increased risk of death
and antipsychotics drugs, and comparison of the development of adverse … disorder; it is not clear if they have been
prescribed for other conditions;
• New or increased adverse … Outcome
measures for harms, or adverse events, are the same as in KQ4 below. … • “Adverse Events” section: adverse events will be analyzed for all controlled trials
as well as
-
effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - KQ 3: Adverse effects. … KQ 3: Adverse effects. No data were reported. … KQ 3: Adverse effects. No data were reported. … KQ3: Adverse effects. No data were reported. … KQ 3: Adverse effects.
-
effectivehealthcare.ahrq.gov/products/back-pain-treatment/clinician
November 15, 2016 - Adverse Effects
For nonpharmacological therapies, assessment of harms was suboptimal. … Pharmacological therapies are associated with increased risk of adverse events when compared with placebo … medium]
Other antidepressants §§
Placebo
Pain
2 SRs
–
[evidence medium]
Table 4 : Adverse … Examples of reported adverse effects included mild bleeding at needling sites with acupuncture, skin … Pharmacological
Pharmacological therapies were associated with increased risk of adverse events when
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effectivehealthcare.ahrq.gov/products/dementia-agitation-aggression/research
March 21, 2016 - Structured Abstract
Objective
To assess the efficacy, comparative effectiveness, and adverse effects … Adverse effects were rarely reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
April 01, 2013 - Transfusion carries a
very low risk of infection and other adverse
events, including transfusion reactions … ,
alloimmunization, overtransfusion, and
immune modulation with theoretically
possible adverse effects … (For example, adverse events that could be
definitively attributed to transfusions were
not reported … in any trial included in this
review for adverse event outcomes.) … Initially, adverse effects that could be
conclusively attributed to erythropoietin treatment
had been
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Eligibility Criteria Interventions Sample Characteristics Screened
Eligible
Randomized
Analyzed Results Adverse … Events and Withdrawals Due to Adverse Events Sponsor Quality
Hruschak, 2021 RCT
Duration: 6 weeks University … Abbreviations: AE = adverse event; BMI = body mass index; CI = confidence interval; COWS = Clinical Opiate … B
Major adverse cardiovascular events: 52 vs. 72
Incidence rate per 10,000 person months (95% CI): 30.12 … event
B: Controls: (n=2,311), patients without an opioid-related adverse event, 1:1 matching based on
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - d Safety outcomes considered were overall adverse events, withdrawals due to adverse events, serious … d Safety outcomes: Overall adverse events, withdrawals due to adverse events, serious adverse events … • Safety (focusing on serious adverse event rates, overall adverse event rates, and withdrawals … due to adverse events) … However, the nature of serious adverse event reporting was
inconsistent, and rates of serious adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - ) and the number of patients with an adverse effect
were recorded. … Key Question 3: Adverse Effects
This question addressed the associated short-term adverse
effects of … high rates of specific adverse effects. … Dizziness
Twenty-three studies reported dizziness as an adverse
effect. … Still, serious or unexpected adverse effects were
uncommon.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - Events:
Stroke
Myocardial infarction
Renal failure
Other Clinically Significant Outcomes and Adverse … Outcomes: pain intensity, mental status, 30-day mortality, serious adverse events (stroke, myocardial … adverse events influenced by pain interventions was examined for the effectiveness review. … Adverse Events Influenced by Pain Management Interventions
Overall, adverse event rates were similar … Conclusions About Benefits and Adverse Events
Abou-Setta AM, Beaupre LA, Jones CA, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - Events:
Stroke
Myocardial infarction
Renal failure
Other Clinically Significant Outcomes and Adverse … Outcomes: pain intensity, mental status, 30-day mortality, serious adverse events (stroke, myocardial … adverse events influenced by pain interventions was examined for the effectiveness review. … Adverse Events Influenced by Pain Management Interventions
Overall, adverse event rates were similar … Conclusions About Benefits and Adverse Events
Abou-Setta AM, Beaupre LA, Jones CA, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Adverse events. … Adverse events. … effect*” OR “adverse reaction*” OR “adverse event*” OR “adverse
outcome*”)
C-3
(TITLE-ABS-KEY … effect*” OR “adverse reaction*” OR “adverse event*” OR “adverse
outcome*”))
(TITLE-ABS-KEY(“hepatitis … effect*” OR “adverse reaction*” OR “adverse event*” OR “adverse
outcome*”)) AND (LIMIT-TO (LIMIT-TO
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - There were 84 studies
that reported at least one adverse event associated with
RFA. … Most of the studies did not report the time of
occurrence of the adverse events. … Major adverse events associated with RFA are relatively
uncommon. … the various adverse events
were not always comparable. … All studies should actively
collect adverse event data from study participants.