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Total Results: 1,401 records

Showing results for "adverse".

1321. Cad-Women-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-treatment_executive.pdf
      August 01, 2012 - What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse drug … Outcomes and effect modifiers • Primary outcomes: major adverse cardiovascular events such as death … • Adverse effects of interventions: adverse drug reactions, radiation exposure, access site complications

1322. Technical Brief Protocol_ 0369 Models of Survivorship Care_2-15-13_v14[1] (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-survivor-care-transition_research-protocol.pdf
      March 27, 2013 - , detection, surveillance, or treatment services.6 This fragmentation of care may have significant adverse … • Adverse … • Mortality • Quality of life • Satisfaction with care • Cost and resource utilization • Adverse … events • Outcomes attributable to the cancer treatment (except for adverse events and other long-term … It seeks to both prevent and control adverse cancer diagnosis and treatment-related outcomes such as

1323. MS Protocol draft_12_12-13 clean[2] (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
      December 17, 2013 - available, people with MS may switch between different medications depending on tolerance, presence of adverse … Adverse effects of intervention(s) □ Any reported adverse events ! … treatment and followup duration or have indeterminable numerators and denominators for outcomes and adverse … participant baseline demographics; type of CIS or MS, MS severity; descriptions and results of outcomes and adverse … Lehmann-Horn K, et al., Current treatment strategies for multiple sclerosis—Efficacy versus neurological adverse

1324. Colorectal-Cancer-Liver-Metastases-Therapies Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
      December 01, 2012 - Titles and abstracts were screened in duplicate for studies that looked at overall survival, adverse … Harms included specific negative effects, including the narrower definition of adverse effects. … Other adverse events are listed in Table 9 of the full report. … SBRT Insufficient One study reported no major complications.69 Other adverse events are reported in … Lack of experience may not only affect patient outcomes but also result in adverse effects; patients

1325. Cystic-Fibrosis-Hgh Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
      August 01, 2012 - RCT found no November 2011 In 1 new RCT, 100% of tx and 97% of controls reported at least one adverse … Stalvey, 201124 See above Adverse events associated with rhGH treatment of CF patients 100% … of tx and 97% of controls reported at least one adverse event (AE). 12 participants in each group … Key Question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key Question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted

1326. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
      August 22, 2008 - KQ 4: In patients with CF, what is the frequency of nonmalignant serious adverse effects resulting from … Adverse effects of interest include, but are not limited to: glucose intolerance, diabetes, and hypoglycemia … KQ 6: In patients with CF, how is efficacy, effectiveness, safety or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety or adverse events of treatment … Important health outcomes in KQ2 and adverse events in KQ4 associated with rhGH will be meta-analyzed

1327. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
      January 27, 2012 - KQ3a: What adverse effects are associated with medications for adults with AUDs in outpatient settings … KQ 3b: How do medications for adults with AUDs compare for adverse effects in outpatient settings? … Evidence for many potential adverse events was insufficient to determine whether the risk was increased … For most of the specific adverse events, point estimates favored placebo (i.e., there were more adverse … In head-to-head studies, the risk of withdrawal due to adverse events was not significantly different

1328. Effective Health Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
      January 01, 2009 - diet including the use of medical foods, amino acids, and micronutrients supplement Outcomes: Cost, adverse

1329. Effective Health Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0288_03-10-2008.pdf
      January 01, 2008 - The efficacy of home uterine activity monitoring in decreasing adverse outcomes in women who are experiencing

1330. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression—An Update to a 2007 Report. (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
      December 01, 2011 - It seems unusual to present a reduced incidence of an adverse effect with an NNT. … Peer Reviewer #5 Results KQ4 Page 123 or page 108, line 44 Adverse Events and Discontinuation Rates: … events such as suicidality, seizures, cardiovascular adverse events, serotonin syndrome, hyponatremia … This is reflected in the differential adverse effect profile of somnolence with mirtazapine. … We included this study in KQ4 on adverse events Peer Reviewer #3 Introduction Table 5.

1331. Disposition of Comments Report for Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m2 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
      June 05, 2013 - ES-8: please clarify SOE for long-term adverse events (insufficient?) Yes, insufficient. … If so, we discuss adverse events associated with medications. … Peer Reviewer 2 Future Research p. 48, adverse events: please specify the SOE for long term adverse … Please specify the SOE for short- term adverse events (moderate). … SOE is insufficient for long term, low for short term adverse events.

1332. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
      January 01, 2016 - Although some experts believe the risk of adverse events would affect patient and clinician adoption … No serious adverse events were reported. … - emergent adverse events were reported most frequently, but were seldom treatment limiting. … The incidence of serious adverse events potentially related to systemic vascular endothelial growth … Rate of serious adverse effects in a series of bevacizumab and ranibizumab injections.

1333. Disposition of Comments for Diagnostic Accuracy of Screening and Treatment of Post-Acute Coronary Syndrome Depression (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
      November 14, 2017 - Second, the analytic framework has 'adverse effects' as a box, but without either a key question or … This should be added, and a discussion of the adverse effects found, if any, should be added to the … A discussion of the adverse outcomes are included in the detailed findings of the report and is one … Peer Reviewer #1 Results Results should add one section on adverse events/harm for both KQ1 and KQ2. … Noncardiac adverse effects were reported in only one study.

1334. CER 5 Renal Artery Stenosis NSD SJ Clean (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
      June 24, 2014 - What adverse events and complications have been associated with aggressive medical therapy or renal

1335. hemangioma-protocol-141223 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_research-protocol.pdf
      December 23, 2014 - What are the adverse outcomes of untreated infantile hemangiomas? … blocker[tiab] OR beta-blockers[tiab] OR angiotensin[tiab] OR intralesional interferon[tiab] OR “adverse … event[tiab] OR undesirable events[tiab] OR undesirable outcome[tiab] OR undesirable outcomes[tiab] OR adverse … effect[tiab] OR adverse effects[tiab] OR adverse reaction[tiab] OR adverse reactions[tiab] OR adverse … event[tiab] OR adverse events[tiab] OR adverse outcome[tiab] OR adverse outcomes[tiab] OR "Postoperative

1336. Menopause Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
      March 01, 2015 - What are the significant agent-specific harms/adverse effects of nonhormone therapies? … Do effectiveness and adverse effects vary among subgroups of participants defined by demographics, … Key Question 3 was a two-part question examining adverse events and long- term effects of nonhormone … For the adverse events question, trials included in Key Question 1 that also reported adverse events … Agent-specific adverse events for nonhormone therapies were categorized using a system recommended by

1337. Nppv-Respiratory-Failure Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
      July 01, 2012 - continuous positive airway pressure (CPAP), associated with less morbidity, lower mortality, fewer adverse … In general, the figure shows that this CER compares morbidity, mortality, adverse events, and health … Adverse events considered are aspiration, secondary infections (including pneumonia and sinusitis), … The safety outcomes were framed to help identify adverse events, including hospital-acquired pneumonia … We included common outcomes of interest such as mortality and adverse events, but also examined more

1338. Fatty-Acids-Cardiovascular-Disease Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_research-protocol.pdf
      April 02, 2015 - are benefits of very long chain polyunsaturated fatty acids (EPA and DHA) for reducing the risk of adverse … Adverse events: • What adverse effects are related to n-3 FA intake or biomarker concentrations ( … • What adverse events are reported specifically among people with CVD or diabetes (in studies of CVD … • Exclude n-3 FA dose ≥6 g/day (except for adverse events) Source: www.effectivehealthcare.ahrq.gov … density lipoprotein cholesterol [LDL-c], total/HDL-c ratio, LDL-c/HDL-c ratio, triglycerides) • Adverse

1339. Renal-Artery-Stenosis Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
      June 01, 2012 - What adverse events and complications have been associated with aggressive medical therapy or renal … No Signal Adverse events: Consistent to the original CER, the adverse events were not adequately assessed … What adverse events and complications have been associated with aggressive medical therapy or renal artery … Adverse events The evidence does not adequately assess comparisons of adverse events between medical … These adverse events occurred at different centers and with Different providers.

1340. Comparative Effectiveness of Strategies to De-escalate Aggressive Behavior in Psychiatric Patients in Acute Care Settings (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
      October 01, 2016 - One RCT43 examined three possible harms: drug-related adverse effects; incidence of abnormal QT (QRS … midazolam vs. a combination of droperidol plus midazolam (3 vs. 1 vs. 2, p=NR).43 Adverse effects … flunitrazepam, no statistical testing reported (3 vs. 3, p=NR).48 Drug-related adverse events 91 … other medication protocols (continued) Adverse effects from medication (continued) Reduction in … events with olanzapine vs. risperidone vs. haloperidol, p=NR.72 Adverse events considered related