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Total Results: 1,851 records

Showing results for "adverse".

101. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - This includes: • Overall adverse events. • Specific adverse events. … • Withdrawals and time to withdrawal due to adverse events. … • Persistence and reversibility of adverse events. 3. … Twelve studies provided adverse-events data for FGAs versus SGAs. … Adverse events were reported in 36 studies comparing SGAs with placebo.

102. Management of Insomnia Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
     August 01, 2017 - review that evaluated current evidence regarding the effectiveness, comparative effectiveness, and adverse … The systematic review assessed the efficacy, comparative effectiveness, and adverse effects of a broad … Psychological and Behavioral Therapy: Adverse Effects �� Evidence was insufficient regarding the adverse … Pharmacological Therapy: Adverse Effects (See Table 3) �� Evidence regarding the long-term (more than … and fractures, head injuries, dementia, and cancer. �� FDA labels warn of several potential severe adverse

103. Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic Review. Evidence Summary. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
     November 01, 2017 - effects • Depression-related outcomes – – • • Adverse effects of treatments Weight … effects 1 study RCT Unknown Imprecisea No difference, findings not reported by specific adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; HR=hazard ratio; MACE=major adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; HR=hazard ratio; MACE=major adverse … Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; MACE=major adverse cardiovascular

104. A Randomized Trial of Epidural Glucocorticoid Injections for Spinal Stenosis: A Brief Summary of Findings for Clinicians (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
     June 01, 2016 - Brief Summary of Findings for Clinicians KEY CLINICAL ISSUE What are the relative effectiveness and adverse … This trial also sought to compare the adverse effects of epidural injections of glucocorticoids plus … There were no differences be- tween injection approaches at 6 weeks. »» There were more reported adverse … Serious adverse events (hospitalization or surgery) were rare among all patients. »» There were higher … Furthermore, the potential adverse effects of systemic glucocor- ticoids (e.g., elevated blood glucose

105. Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/weight-loss-surgery/research
     June 05, 2013 - The following studies were excluded: (1) those with no outcomes of efficacy, effectiveness, or safety/adverse … Short-term rates of adverse events associated with bariatric surgery were relatively low. … long-term studies of bariatric surgery in this particular target population, few data exist about long-term adverse … Short-term adverse events are relatively minor; strength of evidence is low due to small sample size … Strength of evidence is insufficient regarding adverse events in the long-term (2 years or more postsurgery

106. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, … switch rates) o Specific adverse events (including, but not limited to, weight gain, impaired renal … events •Withdrawals due to adverse events •Serious adverse events reported •Withdrawal rates •Switch … Also, adverse events (including, but not limited to, weight gain, impaired renal function, angioedema … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, switch

107. Adverse Effects of First-line Pharmacologic Treatments of Major Depression in Older Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/depression-harms/research-protocol
     February 07, 2018 - Timeline Jul. 20, 2017 Topic Initiated Feb. 7, 2018 Research Protocol Mar. 28, 2019 Systematic Review Adverse … adverse effects of first-line pharmacologic treatments? … effects and comparative adverse effects of first-line pharmacologic treatments? … Outcomes: We are interested in the following adverse effects for KQ1 and KQ2: Any adverse event, as … in those who experienced an adverse events Withdrawal due to adverse events Serious adverse events

108. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
     July 13, 2011 - Adverse effects of interest include but are not limited to nausea, diarrhea, headache, tremor, daytime … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. IV. … events Withdrawals because of adverse events Discontinuation rates because of adverse events … Serious adverse events Specific adverse events or withdrawals because of specific adverse events

109. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - Outcomes: Disorder-specific and -nonspecific adverse events: 1) Overall adverse events. 2) Specific … adverse events: a. … withdrawal because of adverse events, and persistence and reversibility of adverse events … For questions about adverse effects, we will search the U.S. … a dose- related adverse-event analysis.

110. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
     June 01, 2016 - Propranolol was associated with short-term (<6 months) adverse effects such as hypotension, hypoglycemia … Minor adverse effects such as cold extremities, diarrhea, rash, and sleep changes were also reported … . ��� Timolol (topical) Adverse effects 4 353 No adverse effects were observed. ��� STEROIDS All … steroids Adverse effects 16 3291 Steroids were associated with clinically important adverse effects, … effects associated with the different interventions for IH ��Potential long-term adverse effects

111. Draft Appendixes: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/draft-appendixes-plant-based-treatment.pdf
     March 01, 2021 - events and withdrawals due to adverse events for each included study. … Adverse events for comparable THC to CBD ratio versus placebo (short-term, 1 to 6 months followup) … event; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … Cannabis extract CT-921 has a high efficacy– adverse effect profile in a neuropathic pain model. … Adverse effects of medical cannabinoids: a systematic review.

112. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
     September 01, 2011 - Adverse events 22 Low 1 fair trial: no significant differences in ECT + rTMS specific adverse events … VNS vs. sham Adverse events 235 Low 1 fair trial: Some differences in specific adverse events reported … Safety, Adverse Events, and Adherence (KQ 4) Direct evidence. … Specific adverse events. … More careful and consistent assessment of adverse events is required.

113. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
     January 01, 2007 - To date, no study has evaluated proximal clinical measures, long-term effects, and adverse events among … Gastrointestinal adverse events/problems. … Metformin monotherapy was associated with more frequent adverse events compared with the combination … , and consistently report all adverse events (not using aggregated events). … medications in withdrawals due to unspecified adverse events. events 4&5k.

114. Safety of Vaccines Used for Routine Immunization in the United States | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/vaccine-safety/research
     July 01, 2014 - Review methods We reviewed the methodology of the 2011 Institute of Medicine (IOM) consensus report "Adverse … For studies not included in the IOM report, we abstracted data on the presence or absence of adverse … The McHarm instrument was used to evaluate the quality of adverse events collection and reporting in … The vast majority of studies either did not investigate or could not identify risk factors for adverse … Conclusions There is evidence that some vaccines are associated with serious adverse events; however

115. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
     March 01, 2011 - Key Question 3: Adverse Events and Side Effects This Key Question was addressed by 107 studies. … Other adverse events. … Some adverse effects, such as congestive heart failure, may take years to develop, and others, such as … We recommend improvements in adverse event and long-term outcome reporting, with predefined outcomes … High The rates of GI adverse effects were similar for thiazolidinediones and sulfonylureas.

116. Harms of First-Line Depression Treatment in Older Adults | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/depression-harms
     February 07, 2018 - 2017 Topic Initiated February 07, 2018 Research Protocol Adverse … Major Depression in Older Adults March 28, 2019 Systematic Review Adverse

117. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - events (frequency of any adverse events reported in trials) • Withdrawals due to adverse events, time … • Significant (major) adverse events Key Question 2: • Overall adverse events (frequency of any adverse … events reported int rials) • Withdrawals due to adverse events, time to withdrawal due to adverse events … Given the variation in specific adverse event profiles across the SGAs, withdrawals due to adverse events … and ziprasidone Withdrawal Due to Adverse Events • Withdrawals due to adverse events were significantly

118. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antidepressants-update/research-protocol
     July 13, 2011 - Adverse effects of interest include but are not limited to nausea, diarrhea, headache, tremor, daytime … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. Methods A. … events Withdrawals because of adverse events Discontinuation rates because of adverse events Serious … adverse events Specific adverse events or withdrawals because of specific adverse events, including

119. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
     September 23, 2016 - But SGAs also have potentially serious adverse effects (e.g., cardiovascular and endocrinologic adverse … Harms Outcomes: KQ 1: § Overall adverse events (frequency of any adverse events reported in trials … events (frequency of any adverse events reported in trials) § Withdrawals due to adverse events, … ) • Significant (major) adverse events KQ 2: • Overall adverse events (frequency of any adverse events … reported in trials) • Withdrawals due to adverse events, time to withdrawal due to adverse events

120. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
     December 01, 2010 - Outcomes: Disorder-specific and -nonspecific adverse events: Overall adverse events. … Study withdrawals/time to withdrawal because of adverse events. … withdrawal because of adverse events, and persistence and reversibility of adverse events. … For questions about adverse effects, we will search the U.S. … dose-related adverse-event analysis.