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effectivehealthcare.ahrq.gov/health-topics/adverse-effects
March 28, 2019 - Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults
Systematic Review … March 28, 2019
Adverse Effects of First-line Pharmacologic Treatments of Major Depression
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effectivehealthcare.ahrq.gov/health-topics/depression-treatment
April 10, 2020 - of Depression in Children and Adolescents
Systematic Review
April 10, 2020
Adverse … Treatments of Major Depression in Older Adults
Systematic Review
March 28, 2019
Adverse
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effectivehealthcare.ahrq.gov/health-topics/elderly
November 10, 2020 - Integrated Pain Management Programs
Research Protocol
November 10, 2020
Adverse … Treatments of Major Depression in Older Adults
Systematic Review
March 28, 2019
Adverse
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - adverse events of
antidepressants. … Insufficient evidence:
mortality, serious adverse
events, withdrawals due to
adverse events
SSRI … placebo (RCT)
Adverse events
Similar with bupropion XR
(++)23
Serious adverse events
Similar with … placebo (RCT)
Adverse events
Similar with vortioxetine
(+++)25
Serious adverse events
Similar with … duloxetine (RCT)
Adverse events
Fewer with vortioxetine (+++),
NNT 6 (4 to 17)25
Serious adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - adverse events of
antidepressants. … Insufficient evidence:
mortality, serious adverse
events, withdrawals due to
adverse events
SSRI … placebo (RCT)
Adverse events
Similar with bupropion XR
(++)23
Serious adverse events
Similar with … placebo (RCT)
Adverse events
Similar with vortioxetine
(+++)25
Serious adverse events
Similar with … duloxetine (RCT)
Adverse events
Fewer with vortioxetine (+++),
NNT 6 (4 to 17)25
Serious adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
December 23, 2023 - Adverse Events Associated with COVID-19 Pharmaceutical Treatments
Evidence-based Practice Center … Rapid Review Protocol
Project Title: Adverse Events Associated with COVID-19 Pharmaceutical
Treatments … of adverse events
associated with the interventions, regardless of medical indication. … Common Terminology Criteria for
Adverse Events (CTCAE) Version 5. November 27, 2017. … Adverse effects of vaccines: evidence
and causality. 2012
VI.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Serious adverse events, convalescent plasma, 45 days or less
Serious
Adverse
Event
Study ID Days … Serious adverse events, convalescent plasma, more than 45 days
Serious
Adverse Event Study ID Days … Serious adverse events, nirmatrelvir and ritonavir
Serious Adverse
Event
Study
ID
Days n/N … Serious adverse events, molnupiravir
Serious
Adverse
Event
Study ID Days n/N
Intervention
n … Serious adverse events, bebtelovimab
Serious
Adverse
Event
Study ID Days n/N
Intervention
n
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effectivehealthcare.ahrq.gov/products/safety-vaccines/protocol
April 06, 2020 - , the absence of adverse effects, is critically important. … The current CTCAE system (version 5) differentiates 837 adverse events within 26 adverse event domains … criteria assessing two main domains: 108 , 109
Data collection of adverse events
Reporting of adverse … The reporting appraisal will assess whether adverse events, including serious adverse events, were defined … Common Terminology Criteria for Adverse Events classification system (CTCAE) adverse event domains
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effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/clinician
April 06, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … The systematic review summarized herein assesses the effectiveness and adverse consequences of possible … Overview of Research Evidence
The effectiveness and adverse consequences of several interventions … No evidence was found regarding the effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - • Signals from the prior report remain unchanged for adverse events that include
anaphylaxis in adults … There continues to be no evidence of
increased risk of adverse events for vaccines currently recommended … • There remains insufficient evidence to draw conclusions about some rare potential
adverse events … We documented the observed rates of adverse events and assessed the relative
risks between vaccinated … Adverse effects of
vaccines: Evidence and causality.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - effect profiles, but lamotrigine may have a low risk of
adverse effects … (any), prednisolone, and oral magnesium use during pregnancy
may have increased risk of fetal/child adverse … effects, but low-dose aspirin use may
not be associated with increased risk of adverse effects. … No serious maternal adverse effects occurred (low SoE). … ↑ = Increase in adverse effects, ~ = No increase in adverse effects, ??
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - effect profiles, but lamotrigine may have a low risk of
adverse effects … (any), prednisolone, and oral magnesium use during pregnancy
may have increased risk of fetal/child adverse … effects, but low-dose aspirin use may
not be associated with increased risk of adverse effects. … No serious maternal adverse effects occurred (low SoE). … ↑ = Increase in adverse effects, ~ = No increase in adverse effects, ??
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effectivehealthcare.ahrq.gov/products/patient-safety-drug-data/abstract
January 01, 2005 - Medicare administrative claims data offer a valuable informational source for the surveillance of adverse … problems on a rapid turnaround basis, investigating both current and recent past experiences to uncover adverse … under investigation; and
The formulation of statistical approaches to analyze these data to detect adverse … This project will develop a data system and empirical framework for identifying and capturing adverse
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effectivehealthcare.ahrq.gov/sites/default/files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Comparative Adverse Effects of SSRI
vs. Placebo. … adverse events were less…”
This sentence was rephrased. … Comments regarding serious adverse
events and withdrawal due to adverse
events follow the figure. … events” or
“withdrawal due to adverse events”. … due to adverse events”.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Comparative Adverse Effects of SSRI
vs. Placebo. … adverse events were less…”
This sentence was rephrased. … Comments regarding serious adverse
events and withdrawal due to adverse
events follow the figure. … events” or
“withdrawal due to adverse events”. … due to adverse events”.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surveillance-report-1-treatments-for-acute-pain.xlsx
December 22, 2021 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
No new evidence
E-4. … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
No new evidence
E-7. … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
No new evidence
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effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - That is, once the adverse event was experienced, the adverse
event status variable was set to the value … an adverse
event. … status alone; (2)
adverse event status plus baseline severity; (3) adverse event
status plus lagged … adverse event, the probability of the observed
adverse event status was equal to 1 minus the probability … of
experiencing an adverse event.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence is insufficient to draw conclusions about serious adverse
events. … Evidence was insufficient to draw conclusions about serious adverse events. … Evidence was insufficient to draw conclusions about
serious adverse events. … In general, adverse events of these drugs are mild and transient. … However, adverse events of newer
medications require further study.
-
effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events