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effectivehealthcare.ahrq.gov/health-topics/adverse-effects
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
December 23, 2023 - Adverse Events Associated with COVID-19 Pharmaceutical Treatments
Evidence-based Practice Center … Rapid Review Protocol
Project Title: Adverse Events Associated with COVID-19 Pharmaceutical
Treatments … of adverse events
associated with the interventions, regardless of medical indication. … Common Terminology Criteria for
Adverse Events (CTCAE) Version 5. November 27, 2017. … Adverse effects of vaccines: evidence
and causality. 2012
VI.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - adverse events of
antidepressants. … Insufficient evidence:
mortality, serious adverse
events, withdrawals due to
adverse events
SSRI … placebo (RCT)
Adverse events
Similar with bupropion XR
(++)23
Serious adverse events
Similar with … placebo (RCT)
Adverse events
Similar with vortioxetine
(+++)25
Serious adverse events
Similar with … duloxetine (RCT)
Adverse events
Fewer with vortioxetine (+++),
NNT 6 (4 to 17)25
Serious adverse
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Serious adverse events, convalescent plasma, 45 days or less
Serious
Adverse
Event
Study ID Days … Serious adverse events, convalescent plasma, more than 45 days
Serious
Adverse Event Study ID Days … Serious adverse events, nirmatrelvir and ritonavir
Serious Adverse
Event
Study
ID
Days n/N … Serious adverse events, molnupiravir
Serious
Adverse
Event
Study ID Days n/N
Intervention
n … Serious adverse events, bebtelovimab
Serious
Adverse
Event
Study ID Days n/N
Intervention
n
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effectivehealthcare.ahrq.gov/products/COVID-19-pharmaceutical-treatments/research
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Comparative Adverse Effects of SSRI
vs. Placebo. … adverse events were less…”
This sentence was rephrased. … Comments regarding serious adverse
events and withdrawal due to adverse
events follow the figure. … events” or
“withdrawal due to adverse events”. … due to adverse events”.
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effectivehealthcare.ahrq.gov/products/depression-harms/research
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effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - • Signals from the prior report remain unchanged for adverse events that include
anaphylaxis in adults … There continues to be no evidence of
increased risk of adverse events for vaccines currently recommended … • There remains insufficient evidence to draw conclusions about some rare potential
adverse events … We documented the observed rates of adverse events and assessed the relative
risks between vaccinated … Adverse effects of
vaccines: Evidence and causality.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - adverse effects of first-line pharmacologic treatments? … effects and comparative adverse effects
of first-line pharmacologic treatments? … Outcomes:
We are interested in the following adverse effects for KQ1 and KQ2:
• Any adverse event … , as in those who experienced an adverse events
• Withdrawal due to adverse events
• Serious adverse … Effects
• Adverse events
• Withdrawal due to adverse
events
• Serious adverse events
• Hospitalization
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - effect profiles, but lamotrigine may have a low risk of
adverse effects … (any), prednisolone, and oral magnesium use during pregnancy
may have increased risk of fetal/child adverse … effects, but low-dose aspirin use may
not be associated with increased risk of adverse effects. … No serious maternal adverse effects occurred (low SoE). … ↑ = Increase in adverse effects, ~ = No increase in adverse effects, ??
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effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - That is, once the adverse event was experienced, the adverse
event status variable was set to the value … an adverse
event. … status alone; (2)
adverse event status plus baseline severity; (3) adverse event
status plus lagged … adverse event, the probability of the observed
adverse event status was equal to 1 minus the probability … of
experiencing an adverse event.
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effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
May 29, 2025 - Resolution of
diverticulitis, recurrent
diverticulitis,
avoidance of surgery,
morbidity, mortality,
adverse … events
Diagnostic accuracy,
adverse events
Occult colorectal cancer,
recurrent diverticulitis … ,
adverse events
Resolution of
diverticulitis,
morbidity, mortality,
adverse events
Recurrent … diverticulitis,
adverse events
Timing All All Acute vs. convalescent All All
Setting Inpatient,
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effectivehealthcare.ahrq.gov/products/chemotherapy-dental/research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events
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effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
May 29, 2025 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Akgol Gur, 2020 Emergency department … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … B
Proportion with adverse events not reported A vs. … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
da Silva, 2021 Outpatient Brazil
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effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence is insufficient to draw conclusions about serious adverse
events. … Evidence was insufficient to draw conclusions about serious adverse events. … Evidence was insufficient to draw conclusions about
serious adverse events. … In general, adverse events of these drugs are mild and transient. … However, adverse events of newer
medications require further study.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … event” should generally be the default term over “adverse effect” or “adverse
reaction/adverse drug … Adverse
reaction/adverse drug
reaction
An adverse effect specifically associated with a drug. … Severe adverse event An adverse event whose intensity is considered severe (including “nonserious” adverse
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effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … event” should generally be the default term over “adverse effect” or “adverse
reaction/adverse drug … Adverse
reaction/adverse drug
reaction
An adverse effect specifically associated with a drug. … Severe adverse event An adverse event whose intensity is considered severe (including “nonserious” adverse
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effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - • Opioids are probably associated with increased risk of short-term adverse events
versus nonopioid … pharmacologic therapy for acute pain, including any adverse
event, study withdrawal due to adverse … events, nausea, dizziness, and somnolence,
but serious adverse events are uncommon in randomized trials … Opioids were associated with increased risk of short-term adverse events (any
adverse event, study withdrawal … due to adverse events, dizziness and nausea) for both
comparisons.