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Showing results for "adverse".

81. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - In children with JIA, do the rate and type of adverse events differ between: a. … The rate and type of adverse events did not differ between treatment groups in these studies. … comparisons of the rate and type of adverse events among the various DMARDs. … • Reporting of adverse events. … Few high-quality data are available regarding the adverse events associated with DMARDs.

82. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - Also, ACEIs are associated with well-known adverse events not shared by ARBs, including cough (estimated … For adult patients with essential hypertension, how do ACEIs and ARBs differ in safety,4 adverse events … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, and switch … For RCTs, this translates to a difference in rates safety, adverse events, tolerability, to Moderate … There was no evidence of differences in rates of other commonly reported specific adverse events.

83. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - The direct adverse events, tolerability, Low (DRI vs. … In the four studies that did report episodes of ARB) angioedema, this adverse event was observed only … event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, and … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, and switch … rates], as the latter may or may not be due to identifiable adverse events.)

84. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research
    December 01, 2019 - with stent thrombosis (relative risk [RR] = 1.52; 95% confidence interval [CI], 1.17 to 1.97); major adverse … a dominant model, gain-of-function alleles were significantly associated with reduced risk of major adverse … , studies suggested that increased on-clopidogrel reactivity was associated with increased rates of adverse … evidence to support an association between loss-of-function CYP2C19 variants and increased risk of adverse … found evidence that high on clopidogrel platelet reactivity is associated with an increased risk of adverse

85. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
    December 01, 2019 - Adverse effects of interest include but are not limited to nausea, diarrhea, headache, tremor, daytime … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. Methods A. … events Withdrawals because of adverse events Discontinuation rates because of adverse events Serious … adverse events Specific adverse events or withdrawals because of specific adverse events, including

86. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - Response Protocol Project Title: Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse … The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … effects (e.g., bleeding).7,8 The 2019 National Action Plan for Adverse Drug Event Prevention (ADE … US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. … Advancing Medication Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.

87. Safety of Vaccines Used for Routine Immunization in the United States | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/vaccine-safety/research
    April 01, 2020 - For studies not included in the IOM report, we abstracted data on the presence or absence of adverse … The McHarm instrument was used to evaluate the quality of adverse events collection and reporting in … The vast majority of studies either did not investigate or could not identify risk factors for adverse … Conclusions There is evidence that some vaccines are associated with serious adverse events; however … for Locally Advanced Gastric Adenocarcinoma Rapid Evidence Product Mar 06, 2024 Adverse

88. Kidney-Stone-Prevention Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
    March 01, 2013 - specific adverse events. … Key Findings Overall • Adverse effects assessed by withdrawals and withdrawals due to adverse effects … The two trials that reported specific adverse events reported no individual adverse event in more than … (e.g., any, serious adverse effects, adverse effects causing withdrawal, predefined specific adverse … conditions as well as any adverse events, serious adverse events, adverse events causing withdrawal

89. Research White Paper: Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
    November 01, 2020 - Events of Interest Adverse Events Depression treatment-related adverse events. … The adverse events measure also required a modification to capture adverse events related to procedures … Additional procedure codes were added to the Adverse Event value sets. … Potential challenges related to the availability of PHQ-9, adverse event, suicide, and mortality data … Adverse Events Data The intent of the adverse events measure is to capture all adverse events related

90. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/allergy-seasonal/research-protocol
    December 01, 2020 - Adverse effects of intranasal antihistamines may include a bitter aftertaste. … Adverse local effects may include nosebleeds, stinging, burning, and dryness. … Local adverse effects may include nosebleeds and nasal and oral dryness. … How do adverse effects vary with intermittent or continuous use? … Table 4 lists systemic and local adverse effects of interest.

91. Diagnosis and Management of Gout: Current State of the Evidence | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/gout/clinician
    April 01, 2021 - evidence high] 1 systematic review NR No statistically significant differences in overall adverse … Effects Associated With Pharmacological Agents Used To Manage Gout Intervention Adverse Effects … effects include bone marrow suppression, aseptic meningitis, and dermatological adverse events Serious … adverse effects include gastrointestinal perforations, ulcers, and increased risk of heart attack or … Allopurinol Nausea, upset stomach, diarrhea, and elevated liver enzymes Rare but serious adverse

92. S89 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s89.pdf
    October 01, 2007 - ORIGINAL ARTICLE Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events Tracy … events, hold promise to allow earlier identification of adverse events. … Active surveillance of vaccine safety: a system to detect early signs of adverse events. … Poisson sequential sampling modified towards maximal safety in adverse event monitoring. … Prompt, active, population-based identification of adverse drug reaction signals.

93. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - The intranasal route was common in studies reporting adverse events for the comparison of opioids versus … Analytic framework Abbreviations: AE=adverse event; KQ=Key Question Data Sources We searched MEDLINE … Opioids may cause fewer adverse events than ketamine, primarily administered IN. … Opioids may cause more adverse events than NSAIDs, administered primarily IV. … evidence suggests that opioids may cause fewer total adverse events than ketamine.

94. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - Serious adverse events are more common in patients who received lasmiditan than placebo. … Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … pharmacologic therapy for acute pain, including any adverse event, study withdrawal due to adverse … Large increases in withdrawal due to adverse events were seen with oxcarbazepine.

95. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
    August 06, 2018 - Effects"] or [mh /AE,CI,DE,MO,PO,TO] or adverse effect*:ti,ab or adverse event*:ti,ab or adverse … reaction*:ti,ab or "adverse outcome":ti,ab or "adverse outcomes":ti,ab or [mh "Adverse Drug Reaction … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome … Effects"] or [mh /AE,CI,DE,MO,PO,TO] or adverse effect*:ti,ab or adverse event*:ti,ab or adverse … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome

96. Radiotherapy Treatments for Head and Neck Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/head-neck-cancer-update/clinician
    December 01, 2019 - This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … The present review assessed the comparative effectiveness and adverse effects of 3DCRT, IMRT, SBRT, and … Clinical Bottom Line Summary of Key Findings and Strength of Evidence for the Benefits and Adverse … , 3DCRT, SBRT, and PBT: In achieving tumor control and improving patient survival In reducing adverse … methods Using more rigorous standardized reporting such as prespecified systematic collection of adverse

97. Recurrent Nephrolithiasis in Adults: A Comparative Effectiveness Review of Preventive Medical Strategies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/kidney-stone-prevention/research-protocol
    December 01, 2019 - Does the risk of adverse effects differ according to patient baseline diet and fluid intake? … Does the risk of adverse effects differ according to characteristics of stone history? … Does the risk of adverse effects differ according to patient baseline diet and fluid intake? … Does the risk of adverse effects differ according to characteristics of stone history? … The rationale for the shorter required duration for studies reporting adverse effects is that many adverse

98. Prioritization and Selection of Harms for Inclusion in Systematic Reviews (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - Harms are Adverse Events or Complications • Definition of harms: ► Adverse events or complications … What is a Serious Adverse Event? … What is a Serious Adverse Event? … Consider Composite Adverse Events (II) • “Serious adverse events” or “withdrawal due to adverse events … Consider Composite Adverse Events (I) 6. Consider Composite Adverse Events (II) 7.

99. Pharmacotherapy for Adults With Alcohol Use Disorder (AUD) in Outpatient Settings | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/alcohol-misuse-drug-therapy/clinician
    January 01, 2021 - a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse … Table 3: Mechanism of Action of Medications Used in the Treatment of AUD and Their Adverse Effects … Medication Adult Dosing Mechanism of Action Common Adverse Effects Contraindications … c The prescribing information sheet for topiramate lists warnings for several serious adverse effects … Clinicians are advised to refer to the prescribing information sheet for additional information on adverse

100. Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ptsd-adult-treatment-update/research-2018
     October 01, 2019 - The majority of psychological studies reported no information about adverse events; pharmacological treatment … studies did not appear to be associated with any significant adverse events (only venlafaxine appears … Studies provided insufficient strength of evidence for serious adverse events associated with any treatments … The majority of psychological studies reported no information about adverse events. … treatments), differences in treatment benefits by trauma type or other patient characteristics, and adverse