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Total Results: 2,005 records

Showing results for "adverse".

61. Management of Infantile Epilepsies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
    March 01, 2023 - events for Lamotrigine Adverse Event Outcomes for Lamotrigine Findings Conclusion SOE   Non-serious … events for Stiripentol Adverse Event Outcomes for Stiripentol Findings Conclusion SOE   Any adverse … events for Topiramate Adverse Event Outcomes for Topiramate Findings Conclusion SOE   Bronchitis One … Adverse Event Outcomes for Modified Atkins Diet Findings Conclusion SOE   Specific side Effects One … For diets, adverse effects were generally not reported.

62. Hip-Fracture-Pain Clinician (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
    May 01, 2011 - and Epidural Anesthesia: The evidence is insufficient to understand the effectiveness, benefits, or adverse … for pain relief, but the data are too limited to draw conclusions about the benefits or harms. ��� Adverse … Events Overall, adverse event rates were similar in both treated and control groups, but studies were … Serious adverse events such as myocardial infarction, stroke, and renal failure were either rarely reported … For all modalities, the evidence is generally inadequate to estimate harms and the incidence of adverse

63. Improving Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
    December 01, 2019 - antibiotic prescribing compared with usual care that also had low-strength evidence of not causing adverse … to 72% overall prescribing reduction; similar continuing symptoms, limited activity, missing work, adverse … Other interventions had evidence of improved or reduced prescribing, but evidence on adverse consequences … Other interventions also reduced prescribing, but evidence on adverse consequences was lacking, insufficient … should use a complex intervention framework and better evaluate measures of appropriate prescribing, adverse

64. Rheumatoid-Arthritis-Medicine Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
    April 01, 2012 - Low Discontinuation rates and severe adverse events higher with infliximab. … Low No differences in adverse events in efficacy studies. … Low No differences in adverse events in efficacy studies. … Low No differences in adverse events in efficacy studies. … Low No differences in serious adverse events between groups.

65. Data Development for Patient Safety — A Pilot Study using Medicare Part B Drug Data | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/patient-safety-drug-data/abstract
    April 01, 2018 - Medicare administrative claims data offer a valuable informational source for the surveillance of adverse … problems on a rapid turnaround basis, investigating both current and recent past experiences to uncover adverse … under investigation; and The formulation of statistical approaches to analyze these data to detect adverse … This project will develop a data system and empirical framework for identifying and capturing adverse

66. Diagnosis and management of goutKey questions: What is the accuracy of clinical criteria only in the diagnosis of acute gouty arthropathy instead of synovial fluid analysis? In adults with a history of gout, do… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/diagnosis-and-management-of-goutbr-key-questionsbr-ol-liwhat-is-the-accuracy-of-clinical-criteria-only-in-the-diagnosis-of-acute-gouty-arthropathy-instead-of-synovial-fluid-analysisli-liin-adults-with-a-history-of-gout-do-re
    November 01, 2017 - Do effectiveness and adverse effects of treatment differ according to patient baseline uric acid levels … Does the risk of adverse effects differ according to patient baseline diet and fluid intake? … Does the risk of adverse effects differ according to joint vs. systemic involvement in gout? … Does the risk of adverse effects differ according to patient baseline diet and fluid intake? … Does the risk of adverse effects differ according to characteristics of (joint/ gout/systemic) In

67. Management of Infantile Hemangioma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/clinician
    December 01, 2019 - Table 2: Summary of Findings and Strength of Evidence for Adverse Effects of Treatment Interventions … important adverse effects such as hypotension, bradycardia, bronchospasm, hypoglycemia, and seizures … Minor adverse effects such as cold extremities, diarrhea, rash, and sleep changes were also reported. … [evidence medium] Timolol (topical) Adverse effects 4 353 No adverse effects were observed … [evidence low] Steroids All steroids Adverse effects 16 3,291 Steroids were associated

68. Treatment for Restless Legs Syndrome | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/restless-legs/research
    December 01, 2019 - assessed RLS symptom impact, sleep scale scores, disease-specific quality of life, withdrawals, and adverse … We included observational studies that assessed long-term (>6 months) treatment adverse effects and withdrawals … Dopamine agonists resulted in more patients who experienced at least one adverse event (high-strength … Treatment withdrawals were due to lack of efficacy (6% to 37%) as well as augmentation and other adverse … Adverse effects of pharmacologic therapies and long-term treatment withdrawals due to adverse effects

69. Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive Disorder | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/major-depressive-disorder/research
    December 01, 2019 - Patients treated with SGAs had a higher risk of experiencing adverse events or discontinuing treatment … because of adverse events than patients treated with CBT, acupuncture, or St. … overall findings indicated no statistically significant differences in benefits but a lower risk of adverse … SGAs, in general, lead to a higher risk of adverse events than nonpharmacological treatment options. … The evidence is insufficient to form conclusions about differences in serious adverse events, such as

70. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/rheumatoid-arthritis-medicine-update/final-report-update-2018
    October 01, 2019 - Rates of serious adverse events and discontinuations because of adverse events may not differ between … Activity Score (DAS), radiographic joint damage, all discontinuations, and discontinuations due to adverse … no significant differences emerged between any DMARDs for rates of discontinuation attributable to adverse … events or serious adverse events (low SOE for adalimumab, certolizumab pegol, etanercept, infliximab … Overall rates of adverse events and discontinuation were similar among patients given csDMARDs, TNF biologics

71. Evidence Summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2022 Update (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - There was no increase in risk of serious adverse events or withdrawal due to adverse events. … Some nonopioid treatments had frequent overall adverse events and some less frequent yet serious adverse … effects, while nonpharmacological treatments typically reported few adverse events.10 Cannabinoids … Other prioritized adverse events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … The evidence on adverse events with cannabis-related products is much less robust than the evidence

72. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research-protocol
    December 01, 2019 - Outcomes: Disorder-specific and -nonspecific adverse events: Overall adverse events. … Study withdrawals/time to withdrawal because of adverse events. … withdrawal because of adverse events, and persistence and reversibility of adverse events. … For questions about adverse effects, we will search the U.S. … dose-related adverse-event analysis.

73. S96 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s96.pdf
    October 01, 2007 - Pollock, MD* Background: Adverse drug events (ADEs) are an important cause of patient injury. … Adverse drug event data collection, National Elec- tronic Injury Surveillance System-Cooperative Adverse … The FDA safety information and adverse event reporting program. … How the US Food and Drug Administration defines and detects adverse drug events. … Incidence of adverse drug events and potential adverse drug events. Implications for prevention.

74. Making Healthcare Safer IV: Patient Monitoring Systems To Prevent Failure To Rescue | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/patient-monitoring-systems/rapid-research
    January 01, 2025 - systems that scan patient data for signs of clinical deterioration to alert a clinician of a potential adverse … transition to higher level of care, hospital length of stay, measurement of alarm/alert fatigue, or serious adverse … Product Feb 09, 2024 Computerized Clinical Decision Support To Prevent Medication Errors and Adverse

75. Bladder-Cancer-Non-Muscle-Invasive Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
    October 01, 2015 - Adverse Effects: Tests We included seven studies that evaluated adverse effects of various tests for … Adverse Effects: Treatments This Key Question addressed adverse effects of various treatments, including … events (SOE: low for local adverse events; insufficient for systemic adverse events). … MMC: Systemic adverse events Low BCG was associated with increased risk of any systemic adverse event … gemcitabine: Systemic adverse events Low There were no differences in systemic adverse events (1

76. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - See Key Question 3 on adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events.

77. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - See Key Question 3 on adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events. … (Low) Mixed results for specific adverse events.

78. Radiation Therapy for Brain Metastases: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-brain-metastases/protocol
    June 01, 2021 - The broader inclusion criteria for adverse event data take into account that rare adverse events are … of adverse events The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting will also assess whether adverse events, including serious adverse events, were defined … We will use the authors' classification of serious adverse events. … events) Number of patients with serious adverse events Number of adverse events Any specific

79. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
    January 01, 2020 - In the results section, each table of adverse events is labeled ‘reported adverse events.’ … Line 33- How are serious adverse events defined? … events,” “systemic adverse events,” “one or more adverse events” or “serious adverse events,” rather … The study collected only serious adverse events. … events,” “systemic adverse events,” “one or more adverse events” or “serious adverse events” rather

80. First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research
    December 01, 2019 - disorder, with a focus on core illness symptoms, functional outcomes, health care system utilization, and adverse … Adverse events No differences were found in mortality for chlorpromazine versus clozapine and haloperidol … The most frequently reported adverse events with significant differences were extrapyramidal symptoms … Data were sparse for the four key adverse events deemed a priori to be most clinically important.