-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-266-cdd-executive-summary.pdf
November 01, 2023 - with radiculopathy and 1-level disease (SOE: Low), but the likelihood of
experiencing any serious adverse … (SOE)
Pain;
Effect
(SOE)
Function;
Effect
(SOE)
Quality of
Life;
Effect
(SOE)
Adverse … (SOE)
Pain;
Effect
(SOE)
Function;
Effect
(SOE)
Quality of
Life;
Effect
(SOE)
Adverse … However, there were some differences in the
frequency of adverse events for some comparisons. … Limited evidence also suggests a
lower likelihood of experiencing any serious adverse event with ACDF
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - I want the best treatment:
Clinical Outcome
symptom relief
partial relief
partial relief
Adverse … Events
high blood pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$ … Events
high blood pressure
high blood pressure
No adverse events
Out-of-Pocket Costs
5 US$ … events
Response
Remission
No relapse
Efficacy
Sexual dysfunction
Other adverse … events
Disease
specific QoL
Adverse events
Serious adverse events
Adverse events
Prioritize
-
effectivehealthcare-admin.ahrq.gov/products/depression-harms/research-protocol
May 01, 2019 - We replaced the term "harms" with "adverse effects" based on input from the KI panel suggesting that … adverse effects of first-line pharmacologic treatments? … effects and comparative adverse effects of first-line pharmacologic treatments? … Outcomes:
We are interested in the following adverse effects for KQ1 and KQ2:
Any adverse event, … as in those who experienced an adverse events
Withdrawal due to adverse events
Serious adverse events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - The current CTCAE system (version 5)
differentiates 837 adverse events within 26 adverse event domains … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting appraisal will assess whether adverse events, including serious adverse
events, were defined … Common Terminology Criteria for Adverse Events
classification system (CTCAE) adverse event domains … Common Terminology Criteria for Adverse Events classification system (CTCAE) adverse event domains
-
effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/clinician
December 01, 2019 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments had few minor adverse effects. … Access the full report for detailed findings on the comparative effectiveness and adverse effects … Most Common Adverse Effects
FDA = U.S. … Substantial and lifealtering adverse events sometimes occur after surgery for fecal incontinence, and
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effectivehealthcare-admin.ahrq.gov/products/epilepsy-medicine/research
December 01, 2019 - The risk of withdrawing due to adverse events and the risk of several adverse events including fatigue … receiving carbamazepine sustained or controlled release products but are more likely to withdraw due to adverse … The risk of certain adverse events including fatigue, somnolence, nausea, and alopecia were significantly … and phenytoin provided epilepsy control similar to newer antiepileptic medications, but there were adverse … However, these adverse events did not significantly increase the risk of withdrawals.
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effectivehealthcare-admin.ahrq.gov/products/childhood-depression/protocol
October 01, 2020 - *:ti,ab or "adverse outcome":ti,ab or "adverse outcomes":ti,ab or [mh "Adverse Drug Reaction Reporting … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome" … OR TX "adverse outcomes" OR TX “adverse reaction” OR TX “adverse reactions” OR TX “chemically induced … *:ti,ab or "adverse outcome":ti,ab or "adverse outcomes":ti,ab or [mh "Adverse Drug Reaction Reporting … Effects" OR TX “adverse effect” or TX “adverse event” OR TX “adverse events” OR TX "adverse outcome"
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
June 24, 2014 - Outcome(s): Health outcomes (e.g. mortality, morbidity, adverse events), functional
status, patient … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c. … Does the risk of adverse effects differ according to joint vs. systemic
involvement in gout? … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c. … Does the risk of adverse effects differ according to characteristics of (joint/
gout/systemic)
In
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-diffe
November 01, 2017 - - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk of adverse … - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk of adverse … defined as peripheral artery disease of the lower extremities
Does aspirin reduce the risk of adverse … Is clopidogrel more effective than aspirin in reducing adverse cardiovascular events in PAD? … It is associated with a 5 fold increased risk of adverse cardiovascular events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
September 01, 2016 - is a summary of a systematic review evaluating the evidence regarding the comparative benefits and adverse … evidence suggests that there is a trend toward
a higher rate of treatment discontinuation due to adverse … with SGAs.
�� The evidence is also insufficient to permit conclusions
about differences in serious adverse … Overview of Clinical Research Evidence (Continued)
Table 4: Common Adverse Effects Reported in Studies … effects associated with MDD
treatments, including the potential serious adverse effects
associated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-acute-pain.xlsx
September 21, 2022 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Akgol Gur, 2020 Emergency department … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Cooper, 2021 Outpatient U.S … B
Any adverse event: 52.7% (15/36) vs. 8.8% (3/34), p=0.002
Any severe adverse event: 16.7% (6/36) vs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
September 20, 2022 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Akgol Gur, 2020 Emergency department … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … Events Adverse Events Withdrawals Due To Adverse Events Sponsor Quality
Cooper, 2021 Outpatient U.S … B
Any adverse event: 52.7% (15/46) vs. 8.8% (3/34), p=0.002
Any severe adverse event: 16.7% (6/36) vs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
January 01, 2011 - set of criteria
(attributes and levels):
• I want the best treatment:
Clinical Outcome
Adverse … Drug B
partial relief
high blood
pressure
3 US$
Drug C
partial relief
No adverse … preference
for the alternatives:
• I want the best treatment:
Clinical Outcome
C1 = 0.5
Adverse … events points to:
• Serious adverse events, which points to :
o Suicide and attempted suicide
o … Other serious adverse events
• Adverse events, which points to:
o Sexual dysfunction
o Other adverse
-
effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children/research-protocol
December 01, 2019 - This includes:
Overall adverse events
Specific adverse events
Withdrawals/time to withdrawal … events, withdrawal due to adverse events, persistence and reversibility of adverse events. … events, specific events, withdrawals due to adverse events, time to withdrawal due to adverse events … Adverse events will be recorded for each intervention group including the description of the adverse … dose-adverse event analysis.
-
effectivehealthcare-admin.ahrq.gov/products/migraine-prevention/research-2013
December 01, 2019 - effects, and 26 (95% CI, 10 to 43) would discontinue treatments due to bothersome adverse effects. … Adverse effects leading to treatment discontinuation were examined in 68 RCTs. … effects and treatment discontinuation due to adverse effects. … For episodic migraine, approved drugs are effective but increase risk of adverse effects and treatment … discontinuation due to adverse effects.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - events, withdrawals
because of adverse events, serious adverse events,
specific adverse events (including … because of
adverse events. … of adverse
events. … events,
overall risk of serious adverse events, or discontinuation
due to adverse events. … events, overall
risk of serious adverse events, or discontinuation due to
adverse events.
-
effectivehealthcare-admin.ahrq.gov/products/urinary-incontinence-update/final-report-2018
July 01, 2020 - Serious adverse events are rare for all interventions. … We included UI outcomes (cure, improvement, satisfaction), quality of life, and adverse events. … Quality of life and adverse event outcomes are narratively described.
Results. … Constitutional adverse events (e.g., nausea, insomnia, fatigue) were common with duloxetine (moderate … Common adverse events with pharmacological treatments include dry mouth, nausea, and fatigue.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - adverse effects of first-line pharmacologic treatments? … effects and comparative adverse effects
of first-line pharmacologic treatments? … Outcomes:
We are interested in the following adverse effects for KQ1 and KQ2:
• Any adverse event … , as in those who experienced an adverse events
• Withdrawal due to adverse events
• Serious adverse … Effects
• Adverse events
• Withdrawal due to adverse
events
• Serious adverse events
• Hospitalization
-
effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/research
February 01, 2024 - However, there were some differences in the frequency of adverse events for some comparisons. … However, there were some differences in the frequency of adverse events for some comparisons. … Limited evidence also suggests a lower likelihood of experiencing any serious adverse event with ACDF … ACDF = anterior cervical discectomy and fusion; AE = adverse event; BMP-2 = bone morphogenetic protein … The likelihood of general or specific adverse events, such as need for reoperation/revision surgery,
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - The broader
inclusion criteria for adverse event data take into account that rare adverse events are … adverse events
The appraisal of the data collection method will evaluate the rigor of the adverse … The reporting will also assess whether
adverse events, including serious adverse events, were defined … Number of patients with serious adverse events
2. Number of adverse events
3. … What is a Serious Adverse Event?