-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - • Signals from the prior report remain unchanged for adverse events that include
anaphylaxis in adults … There continues to be no evidence of
increased risk of adverse events for vaccines currently recommended … • There remains insufficient evidence to draw conclusions about some rare potential
adverse events … We documented the observed rates of adverse events and assessed the relative
risks between vaccinated … Adverse effects of
vaccines: Evidence and causality.
-
effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
May 01, 2020 - Nonetheless, withdrawals due to adverse events are often reported even when serious or severe adverse … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … event" should generally be the default term over "adverse effect" or "adverse reaction/adverse drug … Adverse reaction/adverse drug reaction
An adverse effect specifically associated with a drug. … adverse events).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - effect profiles, but lamotrigine may have a low risk of
adverse effects … (any), prednisolone, and oral magnesium use during pregnancy
may have increased risk of fetal/child adverse … effects, but low-dose aspirin use may
not be associated with increased risk of adverse effects. … No serious maternal adverse effects occurred (low SoE). … ↑ = Increase in adverse effects, ~ = No increase in adverse effects, ??
-
effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/research
June 01, 2022 - Small to moderate, dose-dependent increases in withdrawal due to adverse events were found with SNRIs … NSAIDs have increased risk of serious gastrointestinal, liver dysfunction, and cardiovascular adverse … Withdrawal from study due to adverse events was significantly increased with nonopioid drugs, with the … Large increases in risk of adverse events were seen with pregabalin (blurred vision, cognitive effects … Dose viii reductions reduced the risk of some adverse events with SNRI antidepressants.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Comparative Adverse Effects of SSRI
vs. Placebo. … adverse events were less…”
This sentence was rephrased. … Comments regarding serious adverse
events and withdrawal due to adverse
events follow the figure. … events” or
“withdrawal due to adverse events”. … due to adverse events”.
-
effectivehealthcare-admin.ahrq.gov/products/insomnia/clinician
March 01, 2021 - The systematic review assessed the efficacy, comparative effectiveness, and adverse effects of a broad … Psychological and Behavioral Therapy: Adverse Effects
Evidence was insufficient regarding the adverse … Pharmacological Therapy: Adverse Effects ( Table 3 )
Evidence regarding the long-term (more than … FDA labels warn of several potential severe adverse effects for all insomnia medications. … b Adverse effects accompanied by warnings or precautions statements in the FDA labels.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - That is, once the adverse event was experienced, the adverse
event status variable was set to the value … an adverse
event. … status alone; (2)
adverse event status plus baseline severity; (3) adverse event
status plus lagged … adverse event, the probability of the observed
adverse event status was equal to 1 minus the probability … of
experiencing an adverse event.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence is insufficient to draw conclusions about serious adverse
events. … Evidence was insufficient to draw conclusions about serious adverse events. … Evidence was insufficient to draw conclusions about
serious adverse events. … In general, adverse events of these drugs are mild and transient. … However, adverse events of newer
medications require further study.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - for monitoring and detecting adverse drug events. … Detecting adverse drug events is a difficult problem. … Although some adverse drug
reactions are detected early on during clinical trials, serious adverse … stored in the Adverse Event Reporting System (AERS) database. … They observe that the discrimination between adverse
drug events from other adverse clinical events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - • Opioids are probably associated with increased risk of short-term adverse events
versus nonopioid … pharmacologic therapy for acute pain, including any adverse
event, study withdrawal due to adverse … events, nausea, dizziness, and somnolence,
but serious adverse events are uncommon in randomized trials … Opioids were associated with increased risk of short-term adverse events (any
adverse event, study withdrawal … due to adverse events, dizziness and nausea) for both
comparisons.
-
effectivehealthcare-admin.ahrq.gov/products/adhd/research
December 01, 2019 - Structured Abstract
Objectives
(1) Compare effectiveness and adverse events of interventions (pharmacological … high risk for attention deficit hyperactivity disorder (ADHD); (2) compare long-term effectiveness and adverse … Adverse effects were present for preschool children treated with MPH; adverse effects were not mentioned … from administrative databases, provided inconclusive evidence for growth, cerebrovascular, and cardiac adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … event” should generally be the default term over “adverse effect” or “adverse
reaction/adverse drug … Adverse
reaction/adverse drug
reaction
An adverse effect specifically associated with a drug. … Severe adverse event An adverse event whose intensity is considered severe (including “nonserious” adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - events; they may also include common adverse events and other specific adverse events
important … Uncommon or Rare Adverse Events
Evaluating comparative risks of uncommon or rare adverse events in … event” should generally be the default term over “adverse effect” or “adverse
reaction/adverse drug … Adverse
reaction/adverse drug
reaction
An adverse effect specifically associated with a drug. … Severe adverse event An adverse event whose intensity is considered severe (including “nonserious” adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … The systematic review
summarized herein assesses the effectiveness and adverse
consequences of possible … consequences associated with these tests either showed
an increase in some adverse outcomes or was … No evidence was found regarding the
effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - There was no effect on
serious adverse events. … • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive
deficits) and outcomes … Some nonopioid treatments had frequent overall adverse events and some less frequent
yet serious adverse … effects, while nonpharmacological treatments typically reported few
adverse events.8
Cannabinoids … events and dizziness, and
moderate increased risk of serious adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
May 08, 2023 - Making Healthcare Safer IV: Computerized
Clinical Decision Support to Prevent Medication Errors and
Adverse … What is the frequency and severity of medication errors and adverse drug events?
2. … Medication Errors and Adverse
Drug Events. … September 7, 2019. https://psnet.ahrq.gov/primer/medication-errors-and-
adverse-drug-events. … Adverse drug events in ambulatory care.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - For medication-related adverse events,
three possible representations that could potentially be seen … in EHR-extracted data are provided:
1) association is based on the adverse reaction being similar to … as treatment-related and systemic adverse events occurring ≤ 30 days after a surgical
procedure or … Events of Interest Adverse events associated
with medications
Medication-related adverse events, defined … Events of Interest Adverse events associated
with disease progression
Adverse events associated with
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - For medication-related adverse events,
three possible representations that could potentially be seen … in EHR-extracted data are provided:
1) association is based on the adverse reaction being similar to … as treatment-related and systemic adverse events occurring ≤ 30 days after a surgical
procedure or … Events of Interest Adverse events associated
with medications
Medication-related adverse events, defined … Events of Interest Adverse events associated
with disease progression
Adverse events associated with
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
September 21, 2022 - Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Skonnord, 2020 Outpatient Norway … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Akgol Gur, 2020 Emergency department … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
Bloom, 2021 Postoperative to … B
Proportion with adverse events not reported A vs. … Events Adverse Events Withdrawals Due to Adverse Events Sponsor Quality
da Silva, 2021 Outpatient Brazil