-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - But SGAs also have
potentially serious adverse effects (e.g., cardiovascular and endocrinologic adverse … Harms Outcomes:
KQ 1:
§ Overall adverse events (frequency of any adverse events reported in
trials … events (frequency of any adverse events reported in
trials)
§ Withdrawals due to adverse events, … )
• Significant (major) adverse events
KQ 2:
• Overall adverse events (frequency of any adverse events … reported in trials)
• Withdrawals due to adverse events, time to withdrawal due to adverse events
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - events:
1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70
Any adverse … events [(n/N (%)]
1 serious adverse events:
6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events: … Fesoterodine resulted in
higher rates of adverse effects and
discontinuation of treatment due to
adverse … events [(n/N (%)]
1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events … Fesoterodine resulted in higher rates of
adverse effects and discontinuation of treatment due to
adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
March 08, 2012 - Adverse local effects may include
nosebleeds, stinging, burning, and dryness. … Other local adverse effects may include nosebleeds, stinging, burning,
and dryness. … Local adverse effects may include
nosebleeds and nasal and oral dryness. … How do adverse effects vary with intermittent or continuous use? … Table 4 lists systemic and local adverse effects of interest.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
December 01, 2015 - Evidence on adverse effects was
insufficient. … Adverse effects did not differ
between groups. … Data were insufficient for adverse effects. … Withdrawals
due to adverse effects, but not any specific adverse effect
or overall withdrawals, were … long-term use or rare adverse effects.
-
effectivehealthcare-admin.ahrq.gov/products/safety-emerging-methods/overview
November 01, 2017 - Developing Indicators of Inpatient Adverse Drug Events Through Nonlinear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events
Tracy A. … Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events. … Evaluation and Overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug … Evaluation and overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - To assess adverse
effects and treatment discontinuation due to adverse
effects, we analyzed all included … Adverse Effects With Drugs for Chronic Migraine
Onabotulinumtoxin A resulted in adverse effects and … Increase in risk of adverse
effects was dose responsive. … Adverse Effects With Drugs for Episodic Migraine
Bothersome adverse effects leading to treatment
discontinuation … in trials with higher
placebo rates of adverse effects.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - informative
- There is new evidence available for KQ1 (effectiveness,
health outcomes) and KQ3 (adverse … , bone density, and cosmetic adverse effects? … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … , bone density, and cosmetic adverse effects? … , bone density, and cosmetic adverse effects?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - informative
- There is new evidence available for KQ1 (effectiveness,
health outcomes) and KQ3 (adverse … , bone density, and cosmetic adverse effects? … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … , bone density, and cosmetic adverse effects? … , bone density, and cosmetic adverse effects?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
January 17, 2014 - mellitus, what is the
comparative safety of the following treatment options in terms of the following adverse … addition to updating information on the potential benefits of available treatments, conclusions
regarding adverse … There have been a number of potential adverse
events associated with rosiglitazone (e.g. increased
-
effectivehealthcare-admin.ahrq.gov/products/glucocorticoid-injections/clinician
November 01, 2017 - Key Clinical Issue
What are the relative effectiveness and adverse effects of epidural injections of … This trial also sought to compare the adverse effects of epidural injections of glucocorticoids plus … The most common adverse events were fever/infection and headache in the glucocorticoidsplus-lidocaine … Serious adverse events (hospitalization or surgery) were rare among all patients. … Furthermore, the potential adverse effects of systemic glucocorticoids (e.g., elevated blood glucose,
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - due to any adverse event did not
reach statistical significance). … , any GI adverse events
(RR 0.31, 95% CI 0.24 to 0.39), and withdrawals due
to GI adverse events (RR … , 95% CI 0.70 to 0.99), but there was no difference
in risk of GI adverse events, withdrawal due to adverse … events, or withdrawal due to GI adverse events. … events and higher risk of dermatologic
adverse compared to oral NSAIDs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - Overall adverse
event profiles appeared to be similar for
biologic DMARDs and placebo. … for at least 28 weeks.
78.2% had at least one adverse
event (AE), but only 4.6% had a
No safety … Common
adverse events
include: nausea/
vomiting, respiratory
infection, abdominal
pain, abnormal … ACR50
response rates were
Did not conduct
statistical tests on
adverse events data. … Overall adverse
event profiles appeared to be similar for biologic
DMARDs and placebo.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - • BT causes more adverse events
(such as worsening of asthma
symptoms, respiratory infections,
and … • Patients treated with BT developed the following
common adverse events: bronchial irritation, chest … Serious adverse events
occurred more frequently in BT-treated patients than in
patients receiving sham … Serious adverse events attributed to BT
were infrequent, and no deaths were reported. … The risk of adverse events is higher early in treatment,
while benefit is typically observed weeks to
-
effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/research
December 01, 2019 - participate in rehabilitation, return to pre-fracture living arrangements, health services utilization, and adverse … and postoperative pain management, albeit from few perspectives such as reported pain, mortality, and adverse … Although most studies reported on adverse effects, they were short term and not adequately powered to
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - • What factors associated with the patient and her breast
abnormality influence the adverse events of … Studies included for the assessment of possible adverse
events of core needle biopsy (Key Question 2 … Core needle biopsy was
only infrequently associated with serious adverse events. … adverse events) compared to core needle
biopsy. … Our assessment of the strength of evidence for
adverse events is summarized in Table H.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - (i.e. staple-line disruption or ulcer), nutritional deficiencies
- LAGB-specific adverse events: … • Adverse events:
o Short-term:
- mortality
- systemic medical complications (i.e. myocardial … KQ3: What are the potential short term adverse effects and/or complications
involved with bariatric … Outcome
measures for harms, or adverse events, are the same as in KQ3, and KQ5 below. … adverse
events
Adverse reactions to
medications
Figure 1.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - to
structure both interventional and database-oriented studies, particu-
larly those concerned with adverse … and state hospital data—for examining initi-
ation, persistence, and adherence, and the benefits and adverse … events.13 The National Electronic
Injury Surveillance System-Cooperative Adverse Drug Event
Surveillance … Real-time vaccine safety
surveillance for the early detection of adverse events. … A simulation-based evaluation of
methods to estimate the impact of an adverse event on hospital length
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
September 18, 2012 - Our work will expand the consensus
report Adverse Effects of Vaccines: Evidence and Causality, which … (CTCAE) classification system, and serious
adverse events (SAE) will be defined and coded. … The absolute risk of serious adverse events (SAEs) will
also be computed. … event
CTCAE = Common Terminology Criteria for Adverse Events
Hib = Haemophilus influenzae type b … Adverse events of interest, included in electronic search terms
Adverse event Vaccine type
Acute