-
effectivehealthcare-admin.ahrq.gov/products/collections/childhood-cancer-survivorship-care
February 01, 2022 - Studies suggest that more than 60 percent of these survivors will suffer adverse physical, psychosocial … These disease- and treatment-related adverse outcomes can significantly impair the quality of survival … The development of effective strategies to prevent, detect, mitigate, and manage these adverse effects … Adverse outcomes can vary in type (physical, behavioral, or psychosocial health effects) and severity
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
August 01, 2015 - The
present review assessed the comparative effectiveness and
adverse effects of 3DCRT, IMRT, SBRT, … This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … Summary of Key Findings and Strength of Evidence for the Benefits and Adverse Effects of Radiotherapy … 3DCRT, SBRT, and PBT:
�– In achieving tumor control and improving patient survival
�– In reducing adverse … risk of xerostomia might be reduced with the
use of IMRT versus 3DCRT
�� The potential long-term adverse
-
effectivehealthcare-admin.ahrq.gov/products/prioritization-patient-safety-practices
January 01, 2024 - List of PSPs that were merged into one of the PSPs in our revised framework Category Item Adverse Drug … Supported by Clinical Pharmacists The Clinical Pharmacist's Role in Preventing Adverse Drug Events Adverse … Error Staff Education and Training Structured Process Changes/Workflow Redesign Adverse Drug Events: … Reducing Adverse Drug Events in Older Adults Use of Screening Tool of Older People's Prescriptions ( … Adverse Events in Hospitals: A Quarter of Medicare Patients Experienced Harm in October 2018. U.S.
-
effectivehealthcare-admin.ahrq.gov/products/nursing-home-safety/technical-brief
December 01, 2019 - Key safety issues as defined by Agency for Healthcare Research and Quality Common Format criteria are adverse … events such as falls, pressure ulcers, infection, and medication errors/adverse drug events, including … Evidence is lacking on the degree to which national uptake of efficacious interventions targeting adverse … events or factors that may lead to adverse events has occurred, with barriers including staffing costs … between adherence to quality-of-life and person-centered care standards and incidence of some types of adverse
-
effectivehealthcare-admin.ahrq.gov/products/renal-update/research
January 01, 2020 - RRT), other kidney events and function, hypertension events, blood pressure (BP), medication use, and adverse … Procedural adverse events were rare but medication-related adverse events were not reported. … Clinically important adverse events related to PTRAS are rare; however, studies generally did not report … medication-related adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - due to adverse events;
4) Persistence and reversibility of adverse events. … events, withdrawal due to adverse events, persistence
and reversibility of adverse events. … due to adverse events, and persistence and reversibility of adverse
events … Adverse events will be recorded for each intervention group including the description of
the adverse … a dose-adverse
event analysis.
-
effectivehealthcare-admin.ahrq.gov/products/summary-findings
December 01, 2024 - Computerized Clinical Decision Support To Prevent Medication Errors and Adverse Drug Events 1a. … Whereas the TEP encouraged implementation of CDSS to reduce medication errors and adverse drug events … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults 9a. … CDSS to reduce medication errors and adverse drug events. … Adverse Events in Hospitals: A Quarter of Medicare Patients Experienced Harm in October 2018. U.S.
-
effectivehealthcare-admin.ahrq.gov/products/binge-eating/clinician
December 01, 2019 - systematic review evaluating the evidence regarding the effectiveness, comparative effectiveness, and adverse … Adverse effects of BED treatments were mainly associated with medications and were rarely severe. … use of other sympathomimetic drugs for weight loss has been associated with serious cardiovascular adverse … Because studies did not uniformly collect or report adverse events, serious adverse events, and study … discontinuations clearly attributable to adverse events, comparisons of harms across medications were
-
effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
March 01, 2020 - It also found strong evidence that atypical antipsychotics can increase chances of adverse events such … Outcome measures for harms, or adverse events, are the same as in KQ4 below. … Adverse events will be analyzed for all controlled trials as well as observational studies with at least … Adverse events associated with on-label use of the atypical antipsychotic medications will be summarized … “Adverse Events” section: adverse events will be analyzed for all controlled trials as well as observational
-
effectivehealthcare-admin.ahrq.gov/products/disruptive-behavior/research
April 01, 2025 - event, although there were few serious adverse events (SOE: Low). … Study withdrawal due to adverse events was higher with any pharmacotherapy relative to placebo (6 RCTs … , N=911, RR 3.44, 95% CI 1.35 to 8.75), although serious adverse events were rare and not different from … The use of medications was associated with an increased risk of experiencing any adverse event, but serious … adverse events were infrequent and similar to placebo.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - Many questions remain
about the risks of these agents across a spectrum of
adverse events from relatively … In general, adverse events did not differ significantly
between biologic and synthetic DMARDs. … Studies were
too small to assess reliably differences in rare but
severe adverse events. … Studies, however, were too small to assess
reliably differences in rare but severe adverse events. … The
groups did not differ in serious adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - Outcomes including efficacy, impact on quality of life and neurocognition, and
adverse effects are important … • We did not detect consistent differences in serious adverse events, number of
reported adverse … events, adverse events, radiation
necrosis, headaches, fatigue, seizure, vomiting. … Risk of bias varied, 25 trials were terminated
early and the quality of adverse assessment and reporting … Adverse Events
We found no difference in serious adverse events when comparing WBRT plus SRS
with
-
effectivehealthcare-admin.ahrq.gov/products/pneumonia-antibiotic-treatment/research
December 01, 2019 - to clinical response, mechanical ventilation, morbidity, mortality, or rates of antibiotic-related adverse … Clinical response, duration of mechanical ventilation, superinfection, rates of antibiotic-related adverse … events, and infusion-related adverse effects did not differ significantly in any study. … Failure To Rescue – Rapid Response Systems
Rapid Evidence Product
Mar 06, 2024
Adverse
-
effectivehealthcare-admin.ahrq.gov/products/migraine-treatments/research
January 01, 2023 - dihydroergotamine, antiemetics, and acetaminophen, reduce pain but increase the risk of mild and transient adverse … Serious adverse events are more common in patients who received lasmiditan than placebo. … Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … placebo, triptans resolved pain at 2 hours and 1 day, and increased the risk of mild and transient adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Differences in Harms (Adverse Events)
(KQ 4a)
We analyzed adverse-events data from 92 head-to-head
efficacy … Methods of adverse-events assessment in efficacy trials
differed greatly. … , and somnolence were
commonly and consistently reported adverse events. … on most serious
adverse events is insufficient to draw firm conclusions. … Other Severe Adverse Events
The existing evidence on the comparative risk for rare
but severe adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
May 25, 2021 - However, we do
provide all rates of key adverse
events in the Summary of Findings
tables. … We agree that the timing of each
adverse event relates to the vaccine
and particular adverse event. … Maybe “A limited number of studies
included listed adverse events
stratified…”. … Peer Reviewer
#5
Results p. 36, line 43: States “severe and
serious adverse events”. … We pre-specified key adverse events
of interest with our technical expert
panel.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
March 23, 2019 - events
o Maternal
Serious maternal adverse events*
• “Serious” adverse events (including those … events*
o Fetal/infant
Serious fetal/infant adverse events*
• “Serious” adverse events (including … events
o Maternal
Serious maternal adverse events*
• “Serious” adverse events (including those … events*
o Fetal/infant
Serious fetal/infant adverse events*
• “Serious” adverse events (including … ) due
to neonatal/infant adverse events.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
November 04, 2021 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. … NR
Serious adverse events: none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04)
Withdrawals due to adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
February 16, 2022 - Outcomes Quality of Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. … NR
Serious adverse events: none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs … B
% (n/N)
Any adverse event: 88.4% (190/215) vs. 85.2% (184/216), RR 1.02 (95% CI 0.88 to 1.18)
Serious … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04)
Withdrawals due to adverse
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - events and may include common adverse events or other adverse events
important to clinicians and patients … adverse
event,” or “any serious adverse event”; rather, the reports generally focused on specific adverse … “serious adverse events” or “withdrawal due to adverse events,” particularly when
evaluating head-to-head … 4) Are there general (non-specific) harms (e.g., any adverse event, any serious adverse event,
withdrawal … Are there general (non-specific) harms (e.g., any adverse event, any serious adverse event,
withdrawal