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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
    July 01, 2012 - ) requested production of a methods guide for comparative effectiveness reviews that specifically addresses … We also address unique issues that might arise if the test in question is a genetic test, although genetic … consideration in some countries. 3-11 Summary In specifying and setting priorities for outcomes to address
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
    March 10, 2010 - Discussion We suggest the investigators consider including a robust discussion that addresses the variations … We have added text to the discussion section following Key Question 4 to address the potential effects … We have added text to the discussion section following Key Question 3 to address the differences in
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-protocol.pdf
    February 18, 2023 - experience managing ME/CFS may inform management of long COVID, and some proposed models of care address … requires expertise and coordination among multiple specialties, applying a whole-patient perspective that addresses … dual independent review by trained members of the research team for eligibility based on whether they address … Data elements to be abstracted into tables are shown in Table 3, which will be used to address the Guiding
  4. effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
    February 01, 2016 - frameworks to illustrate the questions and outcomes we considered (Figures A and B), and we sought to address … systematic reviews, meta-analysis, editorial, commentary) = 36 • Study of children only = 0 • Study addresses … systematic reviews, meta-analysis, editorial, commentary) = 0 • Study of children only = 0 • Study addresses … for research purposes, but should not be considered current. 23 Discussion This systematic review addresses … To address these limitations, greater standardization of treatment data is required.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
    March 01, 2016 - comorbidities and HIV-related opportunistic infections are disease specific and do not explicitly address … We will exclude publications that are not indexed as empirical studies (e.g., addresses, autobiographies
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-lesions-evaluation_technical-brief.pdf
    December 01, 2014 - Analytic Framework The analytic framework addresses the evaluation of patients with suspicious skin … Whether or not data were available in the literature to address the guiding questions is tabulated in … The available literature addresses the potential benefit of noninvasive ultrasound imaging of skin lesions … Much of the extant literature addresses the technical aspects of the photosensitizers or the available … Although the available literature addresses the potential benefit of this method in directing or limiting
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
    December 20, 2011 - limit for inclusion from 65 years to 60 years  We added specific sub-questions (1.a and 1.b) to address … Transportation o General care coordination, care planning, oversight Post-acute care, which addresses … Specific questions to address the above criteria will be adapted from the RTI item bank for risk of
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
    June 29, 2019 - Methods To address the issues raised by the Guiding Questions, we will develop a conceptual framework … We will address the following four Guiding Questions: Guiding Questions: 1. … of primary studies (along with systematic reviews and clinical practice guidelines) that directly address … literature search will include publications that are indexed as non-empirical studies (e.g., editorials, addresses … Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse., Bonnie
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
    March 21, 2013 - The text in the main report, in the Medical Therapies for KQ1A addresses this question noting, “Mechanism … However, the abstract does not address the quality of evidence on behavioral and CAM therapies. … This should be stated up front, and, I think, in the title, for certainly, they do not address the … They also don’t address progestin dose or potency – there are massive differences in many of these … However, I think that this document should be reconceived and rewritten in a way that addresses the
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
    July 10, 2018 - CPG) on treatment of PTSD.10 This CPG was based on literature available through March 2016, and it addresses … combinations with other interventions, or different timeframes or modalities.10-13 Other recent RCTs address
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
    July 10, 2018 - CPG) on treatment of PTSD.10 This CPG was based on literature available through March 2016, and it addresses … combinations with other interventions, or different timeframes or modalities.10-13 Other recent RCTs address
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
    March 05, 2015 - long-term benefits are included as they are part of the decision-making process, this review did not address … References none Peer Reviewer #2 Appendix none Peer Reviewer #2 General This thorough report addresses … Authors should specifically note that this review does not address the benefits and harms of available … The discussion addresses this matter and we have included in the revised introduction to KQ1 results
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
    August 09, 2013 - design-related bias in diagnostic test studies (see Appendix B).33-35 Each question in the instrument addresses … Effectiveness Reviews (hereafter Methods Guide; see Appendix B).37 Each question in the instrument addresses … For questions on test accuracy, data on accuracy directly address the question, so those data will be … Was this strategy appropriate to address the relevant Key Question of the CER? 3. … Are the inclusion/exclusion criteria appropriate to address the relevant Key Question of the CER?
  14. effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
    June 09, 2021 - We have expanded the implication section of the discussion section to address this comment. … To address this point, we have expanded some sections and refer more often to the detailed methods … We have added the reported serious adverse events to the section as outlined above, which also addresses … To address this point, we have added the findings of this study to the discussion for the readers. … multicenter trial on the topic (NCCTG N107C, Brown et al, lancet oncology 18.8 (2017): 1049-1060.) which addresses
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - Next, we will address when it is appropriate to include observational studies in CERs. … Finally, RCTs generally address efficacy rather than effectiveness. … Assess whether OSs address the review question Are there gaps in trial evidence? … The available OS evidence should then be reviewed to establish if, in fact, it addresses the review questions … Assess whether OSs address the review question Are there gaps in trial evidence?
  16. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - Next, we will address when it is appropriate to include observational studies in CERs. … Finally, RCTs generally address efficacy rather than effectiveness. … Assess whether OSs address the review question Are there gaps in trial evidence? … The available OS evidence should then be reviewed to establish if, in fact, it addresses the review questions … Assess whether OSs address the review question Are there gaps in trial evidence?
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
    November 08, 2012 - Department of Defense, APA, NICE, NHMRC, ISTSS for adults, and ISTSS for children and adolescents) address … received one comment on January 8, but it applied to another report in progress supported by AHRQ that addresses … KQ 4 addresses the absolute and comparative risks of harms and adverse events from these interventions
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
    August 23, 2012 - While the effectiveness of the SLFC assay is not in argument, this comparative effectiveness review addresses … future research section is well-constructed and lays out a framework for more definitive studies to address … We found insufficient evidence to address those areas, indicating a need for targeted research in the … Peer Reviewer #8 General The report does address the important questions.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Systematic reviews of the literature about medical tests must address applicability to real-world decisionmaking … two types of mismatches: (1) literature from other populations and contexts that does not directly address … the replacement test has any merit, or whether reviewing only the more limited, newer data better addresses … As a general principle, reviewers should address applicability as they define their review methods … o Reviewers should document how they will address challenges in including studies that may only partly
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - control and intervention groups, it is not surprising that we found very little direct evidence to address … Current evidence is insufficient to address comparative efficacy in pregnant women. … approach to minimize potential confounding, but observational studies could also be done in a way that addresses … The need for specifically designed research that addresses these problems is substantial.

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