-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
November 30, 2011 - This review defines the methods used to address the comparative effectiveness of antiviral
treatment … Assessing Applicability
Because this review addresses a treatment-naive population, this review
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research.pdf
April 15, 2019 - The S&I Framework presents a good model for data architecture to address the needs of the
OMF. … The S&I Framework represents a comparable architecture to address the needs of the
OMF. … Another dimension addresses change over time, e.g., mortality at five years after a diagnosis of
cancer … ; the latter description addresses an individual patient’s outcome over
time. … Another dimension of outcome measurement addresses surrogate or intermediate
Each component of the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
November 20, 2013 - We did
attempt to address the determinants affecting BNP/NT-
proBNP performance, including age. … We have attempted to address this where possible. … Rev 8 General This report addresses seven key questions regarding the
use of (NT-pro-) BNP to diagnose … We have added sections in the Introduction and
Discussion to address context. … KQ4 addresses and
evaluates those studies that included computational
techniques to assess “added value
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
November 01, 2012 - Addresses inequities, vulnerable populations (including issues for patient subgroups)
5f. … Addresses a topic that has clear implications for resolving important dilemmas in
health and health … The topic was expanded to more broadly address
interventions for the treatment of acute migraines, … Does the question address comparative effectiveness or clinical effectiveness? … Do existing systematic reviews address comparative effectiveness?
17.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_disposition-comments.pdf
January 01, 2013 - Tables address some elements of disease specific
aspects of CM (see above comments) but tables
are … We have edited text in the Conclusion to address the
evidence about resource utilization effects in … Commentator &
Affiliation
Section Comment Response
TEP #1 General
Comments
Key Question 3 addresses … Key Question 1c addresses resource utilization. … These sections were edited to address this point.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - It addresses both monotherapy and combination therapy for the
management of type 2 diabetes in adults
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
July 26, 2012 - It would be good to
include a paragraph that addresses this aspect of stone
pathogenesis
While the … The Executive Summary and Introduction of
the main report both were revised to address
the role of … Peer Reviewer
#6
Introduction Addresses lapses in available literature and RCT's on this topic Thank … The reviewers discuss this
limitation and propose future research projects to address this
issue. … The reviewers discuss this
limitation and propose future research projects to address this
issue.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-lower-limb-protheses-evidence-summary.pdf
September 01, 2018 - These studies either address
or provide sufficient data that allowed us to address the
focused question … Note that this
Key Question did not address satisfaction with the LLP
itself. … However, the majority of the
evidence addresses the question of which LLP component
or configuration … In other words, few studies address the issue
of heterogeneity of treatment effect. … The majority of the evidence
on LLPs addresses the question of which LLP component
or configuration
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
May 20, 2013 - will be used to address questions about harms and adverse events. … empirical studies of design-related
bias in diagnostic test studies.24-26 Each question in the instrument addresses … studies and is consistent with the guidance in the AHRQ Methods
Guide.28 Each question in the instrument addresses … Only high-quality systematic reviews will be included to address KQs 1a and 2a.
E. … Was this strategy appropriate to address the relevant Key Question of the CER?
3.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - symptoms
-The guidelines mention the use of leukotriene
antagonists, which this review
does not address … review was
determined during the protocol
development period at which time
it was determined to address … the FDA approved
tiptropium for use in as young as 6
years of age and since this report
does not address … KQ1b addresses intermittent ICS
use in patients 5 years of age and
older, not only 5 to 11 years of … It directly
addresses the key questions of intermittent (1)
ICS treatment and (2) addition of anticholinergics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-prepub-final-research-table-da.xlsx
January 01, 2019 - weight status (normal vs. obese) and levels of dietary carbohydrate (low vs. high) on GWG (directly addresses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - JACC Vol. 53, No. 25, 2009
Leesar 2009 addresses KQ 2 and is also
included in the PTRAS section (Table … 'future research' would increase clarity and within that
section the important questions requiring address … We believe this addresses this
point.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
October 01, 2016 - research question and setting the modeling goals: Specifying an
answerable research question that addresses … Interpreting and reporting results: Presenting the model findings in a way that
addresses the research … modeled.
6
Term Explanation and Elaboration Comments
Uncertainty
analysis
Analysis that addresses … Report results
clearly and in a way that addresses users’ needs. … Report results clearly and in a way that addresses users’ needs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
January 01, 2011 - support of comparative effectiveness reviews (CERs) for the Effective Health Care Program, it
does not address … Aside from the usual Google search, e-mail
addresses can be identified by searching the author’s institution … PubMed is also a
good source of e-mail addresses, as they are included in the author institution field
-
effectivehealthcare.ahrq.gov/sites/default/files/palliative-care-tools-disposition.pdf
May 04, 2017 - We appreciate the suggestions of tools and address each
below:
We have clarified the definition of … This content is
all on Bereavement and doesn't address the issues of care at
the end of life. … The summary could better delineate how
the current state of assessment addresses these different
uses … Even within the scope that the draft report addresses, there is
a broader dimension that deserves to … The
report deals with how well palliative care addresses the
domains identified by the Consensus Project
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/palliative-care-tools-disposition.pdf
May 04, 2017 - We appreciate the suggestions of tools and address each
below:
We have clarified the definition of … This content is
all on Bereavement and doesn't address the issues of care at
the end of life. … The summary could better delineate how
the current state of assessment addresses these different
uses … Even within the scope that the draft report addresses, there is
a broader dimension that deserves to … The
report deals with how well palliative care addresses the
domains identified by the Consensus Project
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
February 24, 2016 - TEP 3
General Comments This systematic review addresses the
diagnosis of gout. … I
think this is a clear dilemma, which may be
beyond the scope of this review to address. … None of these studies actually directly
addresses the incremental value. … the studies and then detailed narrative
descriptions of each study and prior systematic
review that addresses … We address the issue
of new classification criteria in the introduction
and discussion.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - and Crohn’s disease.
12
Discussion
This systematic review of HSCT in the pediatric
population addresses … We did not address the question of
whether evidence from study of HSCT in adults is
applicable to pediatric
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
October 25, 2010 - Postacute rehabilitation is designed to address sustained impairments across physical,
cognitive, and … and Contribution
Originally, the nominator of this topic requested a review that would broadly address … TBI rehabilitation in adults;
8
however, it did not focus on postacute rehabilitation, nor
did it address … Scale score greater than 2
Multidisciplinary postacute rehabilitation for moderate to severe TBI addresses … We will attempt to address effectiveness by TBI etiology, impairment level, and
comorbidities.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
July 01, 2012 - Scope and Purpose of the Systematic
Review
This report addresses the evidence on the validity and … considered primarily relevant to KQ2,
but they also provided data that permitted extrapolation to
address … No evidence to address this question was identified.
KQ2. … PSA, Gleason score,
and tumor stage when SNPs panel data were added.47
No data were identified to address … No evidence was
identified to address the question of clinical utility.